Zobrazeno 1 - 10
of 13
pro vyhledávání: '"James W Fransen"'
Autor:
Hod Dana, Ondrej Novak, Michael Guardado-Montesino, James W Fransen, Amy Hu, Bart G Borghuis, Caiying Guo, Douglas S Kim, Karel Svoboda
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205444 (2018)
Calcium imaging is commonly used to measure the neural activity of large groups of neurons in mice. Genetically encoded calcium indicators (GECIs) can be delivered for this purpose using non-invasive genetic methods. Compared to viral gene transfer,
Externí odkaz:
https://doaj.org/article/8b88862f4edf4231bf55e26405b11718
Autor:
Juyue Chen, Caitlin M. Gish, James W. Fransen, Emilio Salazar-Gatzimas, Damon A. Clark, Bart G. Borghuis
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107928- (2023)
Summary: Evolution has equipped vertebrates and invertebrates with neural circuits that selectively encode visual motion. While similarities in the computations performed by these circuits in mouse and fruit fly have been noted, direct experimental c
Externí odkaz:
https://doaj.org/article/d6c1fef0267a4c678c11ca1bd080d89e
Autor:
James W Fransen, Bart G. Borghuis
Publikováno v:
Cell Reports, Vol 18, Iss 6, Pp 1356-1365 (2017)
The complexity of sensory receptive fields increases from one synaptic stage to the next. In many cases, increased complexity is achieved through spatiotemporal interactions between convergent excitatory and inhibitory inputs. Here, we present eviden
Autor:
Bart G. Borghuis, James W Fransen
Retinal ganglion cells (GCs) are a functionally diverse neuron population that encodes and transmits distinct representations of the visual image on the retina to target nuclei in the brain. Independent studies of visually-evoked responses, cell morp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98bf289f87f9b7a20ece6970bd57347
https://doi.org/10.1101/819441
https://doi.org/10.1101/819441
Autor:
Caiying Guo, Amy Hu, Bart G. Borghuis, Michael Guardado-Montesino, Ondrej Novak, Karel Svoboda, James W Fransen, Hod Dana, Douglas S. Kim
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205444 (2018)
PLoS ONE
PLoS ONE
Calcium imaging is commonly used to measure the neural activity of large groups of neurons in mice. Genetically encoded calcium indicators (GECIs) can be delivered for this purpose using non-invasive genetic methods. Compared to viral gene transfer,
Publikováno v:
Journal of Neurophysiology. 114:2368-2375
The morphological consequences of retinal photoreceptor degeneration are well documented. Much less is known about changes in visual function during degeneration and whether central visual structures directly reflect changes in retinal ganglion cell
Autor:
Roy G. Soto, Peggy A. Seidman, Richard D. Johnson, James W Fransen, Darrell F. Barker, Jeffrey C. Petruska, Lorne M. Mendell, Sandra M. Garraway, Robert Trainer
Publikováno v:
Journal of Comparative Neurology. 522:1048-1071
Detailed characterization of neural circuitries furthers our understanding of how nervous systems perform specific functions and enables the use of those systems to test hypotheses. We have characterized the sensory input to the cutaneous trunk muscl
Autor:
Gobinda Pangeni, Daniel Palanker, Maureen A. McCall, James Donald Loudin, Jacob G. Light, Alice Adkins, Keith Mathieson, Adewumi N. Adekunle, Machelle T. Pardue, James W Fransen
Photovoltaic arrays (PVA) implanted into the subretinal space of patients with retinitis pigmentosa (RP) are designed to electrically stimulate the remaining inner retinal circuitry in response to incident light, thereby recreating a visual signal wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a092fab1197b55e5509af87aac7326e4
https://europepmc.org/articles/PMC4566954/
https://europepmc.org/articles/PMC4566954/
Autor:
James Demas, Juan P. Fernandez de Castro, Maureen A. McCall, Patrick A. Scott, Henry J. Kaplan, Paul J. DeMarco, James W Fransen
Publikováno v:
Investigative ophthalmologyvisual science. 55(4)
Purpose Human and swine retinas have morphological and functional similarities. In the absence of primate models, the swine is an attractive model to study retinal function and disease, with its cone-rich visual streak, our ability to manipulate thei