Taurolidine antiadhesive properties on interaction with E. coli; its transformation in biological environment and interaction with bacteria cell wall.

Autor: Francesco Caruso, James W Darnowski, Cristian Opazo, Alexander Goldberg, Nina Kishore, Elin S Agoston, Miriam Rossi

Publikováno v: PLoS ONE, Vol 5, Iss 1, p e8927 (2010)

The taurine amino-acid derivative, taurolidine, bis-(1,1-dioxoperhydro-1,2,4-thiabiazinyl-4)methane, shows broad antibacterial action against gram-positive and gram-negative bacteria, mycobacteria and some clinically relevant fungi. It inhibits, in v

Externí odkaz: https://doaj.org/article/a22ca908fce543519b12ea468f0a21d9

RKIP Sensitizes Prostate and Breast Cancer Cells to Drug-induced Apoptosis

Autor: Panayotis Pantazis, James H. Wyche, Stephanie Mott, Rajat Roy, Devasis Chatterjee, Zhe Wang, Corey D. Braastad, James W. Darnowski, Sandy Beach, Bharat B. Aggarwal, Zheng Fu, John M. Sedivy, Yaping Sun, Yin Bai, Yasuhide Kitagwa, Kam C. Yeung, Asok Mukhopadhyay, Evan T. Keller

Publikováno v: Journal of Biological Chemistry. 279:17515-17523

Cancer cells are more susceptible to chemotherapeutic agent-induced apoptosis than their normal counterparts. Although it has been demonstrated that the increased sensitivity results from deregulation of oncoproteins during cancer development (Evan,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7229101ef9f51305a9e3e3a9cfbca5f2
https://doi.org/10.1074/jbc.m313816200

A role for MAP kinase in the antitumor activity of a nucleoside analog

Autor: Katharine A Whartenby, James W Darnowski, Scott M Freeman, Paul Calabresi

Publikováno v: Cancer Gene Therapy. 9:37-43

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85e5e5f8f5200f50157072e9e91588d5
https://doi.org/10.1038/sj/cgt/7700406

Taurolidine antiadhesive properties on interaction with E. coli; its transformationin biological environment and interaction with bacteria cell wall

Autor: Nina Kishore, Elin S. Agoston, James W. Darnowski, Miriam Rossi, Francesco Caruso, Alexander Goldberg, Cristian Opazo

Publikováno v: PloS one 5 (2010): e8927.
info:cnr-pdr/source/autori:Caruso, Francesco; Darnowski, James W.; Opazo, Cristian; Goldberg, Alexander;Kishore, Nina; Agoston, Elin S.; Rossi, Miriam/titolo:Taurolidine antiadhesive properties on interaction with E. coli; its transformationin biological environment and interaction with bacteria cell wall/doi:/rivista:PloS one/anno:2010/pagina_da:e8927/pagina_a:/intervallo_pagine:e8927/volume:5
PLoS ONE, Vol 5, Iss 1, p e8927 (2010)
PLoS ONE

The taurine amino-acid derivative, taurolidine, bis-(1,1-dioxoperhydro-1,2,4-thiabiazinyl-4)methane, shows broad antibacterial action against gram-positive and gram-negative bacteria, mycobacteria and some clinically relevant fungi. It inhibits, in v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cbbc6684352b87de9c79df6c222f85
http://www.cnr.it/prodotto/i/16070

Different effect of benzylacyclouridine on the toxic and therapeutic effects of azidothymidine in mice

Autor: Paul Calabresi, Ruth M. Ruprecht, James W. Darnowski, Shih Hsi Chu, Isa Brunetti, Alfredo Falcone

Publikováno v: Blood. 76:2216-2221

It has been reported that in vitro uridine (Urd) can reverse azidothymidine (AZT) cytotoxicity without decreasing anti-human immunodeficiency virus (HIV) activity. Our studies in mice have shown that daily oral doses of benzylacyclouridine (BAU), an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9846a6e8c52ae4a64f7cc25d8c1e02
https://doi.org/10.1182/blood.v76.11.2216.bloodjournal76112216