Zobrazeno 1 - 10
of 15
pro vyhledávání: '"James W Bowman"'
Autor:
Stephanie Kim, Jianning Ge, Dokyun Kim, Jae Jin Lee, Youn Jung Choi, Weiqiang Chen, James W Bowman, Suan-Sin Foo, Lin-Chun Chang, Qiming Liang, Daiki Hara, Inpyo Choi, Myung Hee Kim, Hyungjin Eoh, Jae U Jung
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0292655 (2024)
Thioredoxin-interacting protein (TXNIP) has emerged as a key player in cancer and diabetes since it targets thioredoxin (TRX)-mediated redox regulation and glucose transporter (GLUT)-mediated metabolism. TXNIP consists of two arrestin (ARR, N-ARR and
Externí odkaz:
https://doaj.org/article/5d3596fab6544fdb99fd65d9c1af3946
Autor:
Mireia Solà Colom, Jelena Vucinic, Jared Adolf-Bryfogle, James W. Bowman, Sébastien Verel, Isabelle Moczygemba, Thomas Schiex, David Simoncini, Christopher D. Bahl
Host-pathogen interactions drive an evolutionary game of cat-and-mouse between a pathogen’s protein virulence factors, the host’s adaptive immune system, and therapeutics targeting the pathogen. There is an urgent need for treatments and prophyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36a7258eedcd3e004d9bbe729458b7e
https://doi.org/10.21203/rs.3.rs-2248327/v1
https://doi.org/10.21203/rs.3.rs-2248327/v1
Autor:
Jose L. Garrido, Matías A. Medina, Felipe Bravo, Sarah McGee, Francisco Fuentes-Villalobos, Mario Calvo, Yazmin Pinos, James W. Bowman, Christopher D. Bahl, Maria Ines Barria, Rebecca A. Brachman, Raymond A. Alvarez
Publikováno v:
Cell reports. 39(9)
Despite SARS-CoV-2 being a "novel" virus, early detection of anti-spike IgG in severe COVID-19 patients may be caused by the amplification of humoral memory responses against seasonal coronaviruses. Here, we examine this phenomenon by characterizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664f6acc9815c4b2de15cd6c2cb0c2d9
https://pubmed.ncbi.nlm.nih.gov/35617962
https://pubmed.ncbi.nlm.nih.gov/35617962
Autor:
Jose L. Garrido, Matias Medina, Felipe Bravo, Sarah McGee, Francisco Fuentes, Mario Calvo, James W. Bowman, Christopher D. Bahl, Maria Inés Barría, Rebecca A. Brachman, Raymond A. Alvarez
Despite SARS-CoV-2 being a “novel” coronavirus, several studies suggest that detection of anti-spike IgG early in infection may be attributable to the amplification of humoral memory responses against seasonal hCoVs in severe COVID-19 patients. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9026d7df2c13aac319f6b4cd4554cea
https://doi.org/10.1101/2021.09.14.460338
https://doi.org/10.1101/2021.09.14.460338
Autor:
James W. Bowman, Karin Nielsen-Saines, Suan-Sin Foo, Weiqiang Chen, Jianning Ge, Jae U. Jung, Yen Chan, Genhong Cheng, Ji-Seung Yoo, Alexandre Bonnin, Younho Choi, Lin-Chun Chang, Patrícia Brasil
Publikováno v:
Nature microbiology
Blood CD14+ monocytes are frontline immunomodulators categorized into classical, intermediate or non-classical subsets, and subsequently differentiated into M1 pro- or M2 anti-inflammatory macrophages on stimulation. Although the Zika virus (ZIKV) ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca3522e5f39d18be6d6a24cc208e356
http://europepmc.org/articles/PMC5678934
http://europepmc.org/articles/PMC5678934
Publikováno v:
Immunity. 48:474-476
Interferon-induced proteins with tetratricopeptide repeats (IFIT) inhibit infection of many viruses by recognizing their RNA, but the mechanisms regulating their remain unclear. We report a crystal structure of cap 0 (m7GpppN)-RNA-bound to human IFIT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b7b8b848c9370459f40b6903f6d046
https://doi.org/10.1016/j.immuni.2018.03.001
https://doi.org/10.1016/j.immuni.2018.03.001
Autophagy is a powerful tool that host cells use to defend against viral infection. Double-membrane vesicles, termed autophagosomes, deliver trapped viral cargo to the lysosome for degradation. Specifically, autophagy initiates an innate immune respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5a5967e0b037b0feb1f1fb32ac96a8
https://europepmc.org/articles/PMC6907743/
https://europepmc.org/articles/PMC6907743/
Autor:
Mi Jeong Kwak, Nam Ki Lee, Kyeong Sik Jin, Cheol-Hee Kim, Jooyoung Lee, Hyunmin Kim, James W. Bowman, J. Dongun Kim, Jae U. Jung, Byung-Ha Oh, Yeon-Gil Kim, Keehyoung Joo, Seong Hoon Kim
Publikováno v:
Nature Microbiology. 2
Many bacteria, including Legionella pneumophila, rely on the type IV secretion system to translocate a repertoire of effector proteins into the hosts for their survival and growth. Type IV coupling protein (T4CP) is a hexameric ATPase that links tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5047dd0a82e953a96145c75b60bbbd
https://doi.org/10.1038/nmicrobiol.2017.114
https://doi.org/10.1038/nmicrobiol.2017.114
Publikováno v:
Handbook of Industrial Chemistry and Biotechnology ISBN: 9783319522852
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4697c704eaf12b07ecb9358ef374c73
https://doi.org/10.1007/978-3-319-52287-6_41
https://doi.org/10.1007/978-3-319-52287-6_41
Autor:
Mude Shi, Rina Amatya, James W. Bowman, Kazuhiro Iwai, Bruce S. Hostager, Shou-Jiang Gao, Jae U. Jung, Mary A. Rodgers
Publikováno v:
mBio
mBio, Vol 6, Iss 6 (2015)
mBio, Vol 6, Iss 6 (2015)
Linear ubiquitination is an atypical posttranslational modification catalyzed by the linear-ubiquitin-chain assembly complex (LUBAC), containing HOIP, HOIL-1L, and Sharpin. LUBAC facilitates NF-κB activation and inflammation upon receptor stimulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8477b2d5325428dc03806fa0605475
http://europepmc.org/articles/PMC4659476
http://europepmc.org/articles/PMC4659476