Zobrazeno 1 - 10
of 78
pro vyhledávání: '"James W, Leahy"'
Autor:
Shannon E. Hill, David Beaulieu-Abdelahad, Andrea Lemus, Jack M. Webster, Santiago Rodriguez Ospina, April L. Darling, Mackenzie D. Martin, Shreya Patel, Liznair Bridenstine, Ronald Swonger, Steven Paul, Roy Blackburn, Laurent Calcul, Chad A. Dickey, James W. Leahy, Laura J. Blair
Publikováno v:
ACS Chemical Biology. 18:1124-1135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6129a08167a81c8a896513b79849deb0
https://doi.org/10.1021/acschembio.2c00919
https://doi.org/10.1021/acschembio.2c00919
Autor:
Logan Tillery, Kayleigh Barrett, Jenna Goldstein, Jared W Lassner, Bram Osterhout, Nathan L Tran, Lily Xu, Ryan M Young, Justin Craig, Ian Chun, David M Dranow, Jan Abendroth, Silvia L Delker, Douglas R Davies, Stephen J Mayclin, Brandy Calhoun, Madison J Bolejack, Bart Staker, Sandhya Subramanian, Isabelle Phan, Donald D Lorimer, Peter J Myler, Thomas E Edwards, Dennis E Kyle, Christopher A Rice, James C Morris, James W Leahy, Roman Manetsch, Lynn K Barrett, Craig L Smith, Wesley C Van Voorhis
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0241738 (2021)
Naegleria fowleri is a pathogenic, thermophilic, free-living amoeba which causes primary amebic meningoencephalitis (PAM). Penetrating the olfactory mucosa, the brain-eating amoeba travels along the olfactory nerves, burrowing through the cribriform
Externí odkaz:
https://doaj.org/article/23d070499b154d11aa93fd5498f6c574
Autor:
Alona Botnar, Grant Lawrence, Steven P. Maher, Amélie Vantaux, Benoît Witkowski, Justine C. Shiau, Emilio F. Merino, David De Vore, Christian Yang, Cameron Murray, Maria B. Cassera, James W. Leahy, Dennis E. Kyle
Publikováno v:
International Journal for Parasitology. 52:733-744
Malaria is a major global health problem which predominantly afflicts developing countries. Although many antimalarial therapies are currently available, the protozoan parasite causing this disease, Plasmodium spp., continues to evade eradication eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e189c9d5cd5dcf417e915e7f746d84e1
https://doi.org/10.1016/j.ijpara.2022.03.003
https://doi.org/10.1016/j.ijpara.2022.03.003
Autor:
Daniel R. Dempsey, Derek A. Nichols, Matthew R. Battistini, Orville Pemberton, Santiago Rodriguez Ospina, Xiujun Zhang, Anne-Marie Carpenter, Brian G. O’Flynn, James W. Leahy, Ankush Kanwar, Eric M. Lewandowski, Yu Chen, David J. Merkler
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Agmatine N-acetyltransferase (AgmNAT) catalyzes the formation of N-acetylagmatine from acetyl-CoA and agmatine. Herein, we provide evidence that Drosophila melanogaster AgmNAT (CG15766) catalyzes the formation of N-acetylagmatine using an or
Externí odkaz:
https://doaj.org/article/b2083b0e3aaf4cd49387f1ef030550cb
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Bitter taste receptors (TAS2Rs) are recognized as being expressed on multiple cell types and organs, including human airway smooth muscle (HASM) cells, where agonists promote significant relaxation to constrictive stimuli. Thus, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b2578fa1a5065711a9e30948c58c43
https://doi.org/10.1021/acsptsci.0c00127
https://doi.org/10.1021/acsptsci.0c00127
Autor:
Gabriela Suarez, Eric M. Lewandowski, Yu Chen, David J. Merkler, Nasha M Rios-Guzman, Karin Claire Prins, Ioannis Gelis, Britney A. Shepherd, James W. Leahy, Ryan L. Anderson, Angelica N McCaskey, Brian G. O'Flynn
Publikováno v:
ACS Chemical Biology. 15:513-523
The growing issue of insecticide resistance has meant the identification of novel insecticide targets has never been more important. Arylalkylamine N-acyltransferases (AANATs) have been suggested as a potential new target. These promiscuous enzymes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3791a5745132aba9dd63b58601dc2eec
https://doi.org/10.1021/acschembio.9b00973
https://doi.org/10.1021/acschembio.9b00973
Autor:
Maria B. Cassera, Emilio F. Merino, Justine C. Shiau, Dennis E. Kyle, Alona Botnar, Benoit Witkowski, Cameron Murray, Grant A. Lawrence, Amélie Vantaux, David De Vore, Christian Yang, Steven P. Maher, James W. Leahy
Malaria is a major global health problem which predominantly afflicts developing countries. Although many antimalarial therapies are currently available, the protozoan parasite causing this disease, Plasmodium spp., continues to evade eradication eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a7d06a8f9386d6d4fef4b43a3b75b52
https://doi.org/10.1101/2021.10.12.464062
https://doi.org/10.1101/2021.10.12.464062
Autor:
Justin K. Craig, Ian Chun, Dennis E. Kyle, Lynn K. Barrett, Craig L. Smith, Kayleigh F. Barrett, James W. Leahy, David M. Dranow, Logan Tillery, Jared W. Lassner, Jan Abendroth, Wesley C. Van Voorhis, Stephen J. Mayclin, Sandhya Subramanian, Isabelle Q. Phan, Brandy Calhoun, Madison J. Bolejack, Douglas R. Davies, Nathan L. Tran, Christopher A. Rice, Jenna Goldstein, Lily Xu, Bram Osterhout, Bart Staker, James Morris, Thomas E. Edwards, Roman Manetsch, Donald D. Lorimer, Peter J. Myler, Ryan M. Young, Silvia Delker
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0241738 (2021)
PLoS ONE
PLoS ONE
Naegleria fowleri is a pathogenic, thermophilic, free-living amoeba which causes primary amebic meningoencephalitis (PAM). Penetrating the olfactory mucosa, the brain-eating amoeba travels along the olfactory nerves, burrowing through the cribriform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1cb665fa036db76aa7e280e813be41
https://doaj.org/article/23d070499b154d11aa93fd5498f6c574
https://doaj.org/article/23d070499b154d11aa93fd5498f6c574
Autor:
Jenna Goldstein, Roman Manetsch, Dennis E. Kyle, Bart Staker, Kayleigh F. Barrett, Ian Chun, Ryan M. Young, Justin K. Craig, James Morris, Peter J. Myler, Christopher A. Rice, Lynn K. Barrett, David M. Dranow, Silvia Delker, Brandy Calhoun, Sandhya Subramanian, Madison J. Bolejack, Lily Xu, James W. Leahy, Stephen J. Mayclin, Bram Osterhout, Wesley C. Van Voorhis, Logan Tillery, Craig L. Smith, Thomas E. Edwards, Douglas R. Davies, Jared W. Lassner, Jan Abendroth, Isabelle Q. Phan, Nathan L. Tran, Donald D. Lorimer
Naegleria fowleri is a pathogenic, thermophilic, free-living amoeba which causes primary amebic meningoencephalitis (PAM). Penetrating the olfactory mucosa, the brain-eating amoeba travels along the olfactory nerves, burrowing through the cribriform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687be1ef8eb545da4b7c6c7d6e1ea985
https://doi.org/10.1101/2020.10.20.327296
https://doi.org/10.1101/2020.10.20.327296
Autor:
Brian G, O'Flynn, Eric M, Lewandowski, Karin Claire, Prins, Gabriela, Suarez, Angelica N, McCaskey, Nasha M, Rios-Guzman, Ryan L, Anderson, Britney A, Shepherd, Ioannis, Gelis, James W, Leahy, Yu, Chen, David J, Merkler
Publikováno v:
ACS chemical biology. 15(2)
The growing issue of insecticide resistance has meant the identification of novel insecticide targets has never been more important. Arylalkylamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96bae39571a2671810df6ff11c61d52b
https://pubmed.ncbi.nlm.nih.gov/31967772
https://pubmed.ncbi.nlm.nih.gov/31967772