Zobrazeno 1 - 10
of 23
pro vyhledávání: '"James W, Conrad"'
Autor:
James W. Conrad, Mark L. Sowers, Dianne Y. Yap, Ellie Cherryhomes, B. Montgomery Pettitt, Kamil Khanipov, Lawrence C. Sowers
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1308 (2023)
Increased expression of the human telomere reverse transcriptase (hTERT) in tumors promotes tumor cell survival and diminishes the survival of patients. Cytosine-to-thymine (C-to-T) transition mutations (C250T or C228T) in the hTERT promoter create b
Externí odkaz:
https://doaj.org/article/4bc5f189d353409db9ab8edea379c2ed
Autor:
James W. Conrad, Valerie J. Harwood
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT Vibrio vulnificus is a naturally occurring, potentially lethal pathogen found in coastal waters, fish, and shellfish. Sewage spills in coastal waters occur when infrastructure fails due to severe storms or age, and may affect bacterial popul
Externí odkaz:
https://doaj.org/article/a90e99e51d3346e8b550e1d9af426281
Autor:
Tuvshintugs Baljinnyam, Mark L Sowers, Chia Wei Hsu, James W Conrad, Jason L Herring, Linda C Hackfeld, Lawrence C Sowers
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0273509 (2022)
The DNA of all living organisms is persistently damaged by endogenous reactions including deamination and oxidation. Such damage, if not repaired correctly, can result in mutations that drive tumor development. In addition to chemical damage, recent
Externí odkaz:
https://doaj.org/article/7d52410c29cf4496b9561cc56bbf4cf7
Autor:
Mark L. Sowers, James W. Conrad, Bruce Chang-Gu, Ellie Cherryhomes, Linda C. Hackfeld, Lawrence C. Sowers
Publikováno v:
Molecules, Vol 28, Iss 3, p 970 (2023)
Although genomic DNA is predominantly duplex under physiological conditions, particular sequence motifs can favor the formation of alternative secondary structures, including the G-quadruplex. These structures can exist within gene promoters, telomer
Externí odkaz:
https://doaj.org/article/a33412c3fbe443a6b6675c6400251f67
Autor:
Tuvshintugs Baljinnyam, James W. Conrad, Mark L. Sowers, Bruce Chang-Gu, Jason L. Herring, Linda C. Hackfeld, Kangling Zhang, Lawrence C. Sowers
Publikováno v:
Chemical Research in Toxicology. 36:162-176
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8f8a28e36166a66dd4aec39d958cea6
https://doi.org/10.1021/acs.chemrestox.2c00172
https://doi.org/10.1021/acs.chemrestox.2c00172
Publikováno v:
Journal of Applied Microbiology. 132:2990-3000
Aims Beach water quality is regulated by faecal indicator bacteria levels, sand is not, despite known human health risk from exposure to beach sand. We compared the performance of three methods to extract bacterial DNA from beach sand as a step towar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d938c36570260d901e3df71bbb30ea
https://doi.org/10.1111/jam.15423
https://doi.org/10.1111/jam.15423
Autor:
Chia Wei Hsu, James W Conrad, Mark L Sowers, Tuvshintugs Baljinnyam, Jason L Herring, Linda C Hackfeld, Sandra S Hatch, Lawrence C Sowers
Publikováno v:
Nucleic acids research. 50(13)
DNA damage drives genetic mutations that underlie the development of cancer in humans. Multiple pathways have been described in mammalian cells which can repair this damage. However, most work to date has focused upon single lesions in DNA. We presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658aab208876de945c45a29a394a5078
https://pubmed.ncbi.nlm.nih.gov/35776119
https://pubmed.ncbi.nlm.nih.gov/35776119
Publikováno v:
Science of The Total Environment. 686:1069-1075
Escherichia coli (E. coli) is frequently used in assessment and regulation of recreational water quality, but it is a general fecal indicator that provides no information about fecal contamination source. Sewage-associated microorganisms and related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03298eccc0908034087e0a789fc0e2b3
https://doi.org/10.1016/j.scitotenv.2019.05.201
https://doi.org/10.1016/j.scitotenv.2019.05.201
Autor:
Cheryl A. Kerfeld, Eva Chase, Jason C. Richardson, Tara L. Harmer, Chris Daum, Emily A. McIntyre, Nicole Shapiro, Kaleigh M. Nelson, Darren S. Dunlap, Brittney D. Moore, Manoj Pillay, Kimmy N. Nguyen, Marcel Huntemann, Neha Varghese, Maki Tabuchi, Christie K. Campla, Michael R. Solone, John Williams, Natalia Ivanova, Rich Boden, Alicia Clum, Zachery R. Staley, William A. Morgan, Elizabeth M. Fahsbender, T. B. K. Reddy, Courtney Lewis, Dawn B. Goldsmith, Gary J. Camper, Christina M. Rodgers, Dimitrios Stamatis, Jessica A. Mine, David G. Parrino, Leila G. Casella, Pauline Wanjugi, Brent L. Schaffer, Elizabeth A. Rampersad, Suzanne Young, Ryan Keeley, Anangamanjari D. Pedapudi, Breanna I. Kussy, Stephanie Lawler, Cody M. B. Porter, Kathleen M. Scott, John H. Paul, Nancy E. Sheridan, Nicholas Ogburn, Paola A. Mancera, James W. Conrad, Nikos C. Kyrpides, Ramond J. Waide, Rebecca P. Pelham, Tanja Woyke, Mercedez C. Cruz, Krishnaveni Palaniappan, Matthew R. Kondoff, Sydney Russel, Sharyn K. Freyermuth, Evan C. McClenthan, Brittany Leigh, Natalia Mikhailova, Swapnil Modi, Amanda M. Preece, Lygia M. Lostal, Devon Marking, Megan K. Bridges, Laura Duran, Kirsten M. Antonen, Marannda K. Lane
Publikováno v:
Environmental Microbiology. 20:2686-2708
Chemolithoautotrophic bacteria from the genera Hydrogenovibrio, Thiomicrorhabdus and Thiomicrospira are common, sometimes dominant, isolates from sulfidic habitats including hydrothermal vents, soda and salt lakes and marine sediments. Their genome s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4999e5d4c9041abf454009e15d97e5c8
https://doi.org/10.1111/1462-2920.14090
https://doi.org/10.1111/1462-2920.14090
Autor:
Valerie J. Harwood, James W. Conrad
Publikováno v:
Microbiology Resource Announcements
The chromosomal methylation statuses of the highly virulent Vibrio vulnificus strain CMCP6 grown in human serum and in seawater are compared here. Growth in seawater resulted in ∼4 times as much methylation as that in human serum, primarily N4-meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48044639a8ffc90d47fe8606ea9b2d09
https://doi.org/10.1128/mra.00419-19
https://doi.org/10.1128/mra.00419-19