Zobrazeno 1 - 10
of 36
pro vyhledávání: '"James Vlasblom"'
Autor:
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
Publikováno v:
iScience, Vol 19, Iss , Pp 1114-1132 (2019)
Summary: Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-ba
Externí odkaz:
https://doaj.org/article/c6301e8c20a347908830d745496bf253
Autor:
Kamran Rizzolo, Jennifer Huen, Ashwani Kumar, Sadhna Phanse, James Vlasblom, Yoshito Kakihara, Hussein A. Zeineddine, Zoran Minic, Jamie Snider, Wen Wang, Carles Pons, Thiago V. Seraphim, Edgar Erik Boczek, Simon Alberti, Michael Costanzo, Chad L. Myers, Igor Stagljar, Charles Boone, Mohan Babu, Walid A. Houry
Publikováno v:
Cell Reports, Vol 20, Iss 11, Pp 2735-2748 (2017)
A comprehensive view of molecular chaperone function in the cell was obtained through a systematic global integrative network approach based on physical (protein-protein) and genetic (gene-gene or epistatic) interaction mapping. This allowed us to de
Externí odkaz:
https://doaj.org/article/f2af40acd84148669d6f31a51b5f7bd6
Autor:
Ashwani Kumar, Natalia Beloglazova, Cedoljub Bundalovic-Torma, Sadhna Phanse, Viktor Deineko, Alla Gagarinova, Gabriel Musso, James Vlasblom, Sofia Lemak, Mohsen Hooshyar, Zoran Minic, Omar Wagih, Roberto Mosca, Patrick Aloy, Ashkan Golshani, John Parkinson, Andrew Emili, Alexander F. Yakunin, Mohan Babu
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 648-661 (2016)
As antibiotic resistance is increasingly becoming a public health concern, an improved understanding of the bacterial DNA damage response (DDR), which is commonly targeted by antibiotics, could be of tremendous therapeutic value. Although the genetic
Externí odkaz:
https://doaj.org/article/9fbd82c0796d4664a9c936ea2215594d
Autor:
Mohan Babu, Roland Arnold, Cedoljub Bundalovic-Torma, Alla Gagarinova, Keith S Wong, Ashwani Kumar, Geordie Stewart, Bahram Samanfar, Hiroyuki Aoki, Omar Wagih, James Vlasblom, Sadhna Phanse, Krunal Lad, Angela Yeou Hsiung Yu, Christopher Graham, Ke Jin, Eric Brown, Ashkan Golshani, Philip Kim, Gabriel Moreno-Hagelsieb, Jack Greenblatt, Walid A Houry, John Parkinson, Andrew Emili
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004120 (2014)
Large-scale proteomic analyses in Escherichia coli have documented the composition and physical relationships of multiprotein complexes, but not their functional organization into biological pathways and processes. Conversely, genetic interaction (GI
Externí odkaz:
https://doaj.org/article/2896e8427bcd49608cc1b53f2c8d503b
Autor:
Mohan Babu, J Javier Díaz-Mejía, James Vlasblom, Alla Gagarinova, Sadhna Phanse, Chris Graham, Fouad Yousif, Huiming Ding, Xuejian Xiong, Anaies Nazarians-Armavil, Md Alamgir, Mehrab Ali, Oxana Pogoutse, Asaf Pe'er, Roland Arnold, Magali Michaut, John Parkinson, Ashkan Golshani, Chris Whitfield, Shoshana J Wodak, Gabriel Moreno-Hagelsieb, Jack F Greenblatt, Andrew Emili
Publikováno v:
PLoS Genetics, Vol 7, Iss 11, p e1002377 (2011)
As the interface between a microbe and its environment, the bacterial cell envelope has broad biological and clinical significance. While numerous biosynthesis genes and pathways have been identified and studied in isolation, how these intersect func
Externí odkaz:
https://doaj.org/article/267b6741cba6464c9b09fc1d98cbfecc
Autor:
Shuye Pu, Andrei L Turinsky, James Vlasblom, Tuan On, Xuejian Xiong, Andrew Emili, Zhaolei Zhang, Jack Greenblatt, John Parkinson, Shoshana J Wodak
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14122 (2010)
Chromatin modification (CM) plays a key role in regulating transcription, DNA replication, repair and recombination. However, our knowledge of these processes in humans remains very limited. Here we use computational approaches to study proteins and
Externí odkaz:
https://doaj.org/article/68d982af51c741bb9f832615d4a2ffc5
Autor:
Nichollas E. Scott, Bhanu Prasad, Mara Zilocchi, Francisco S. Cayabyab, Qingzhou Zhang, Leonard J. Foster, Jocelyn Stockwell, Alex Rajput, Hiroyuki Aoki, Yasushi Okazaki, Ramy H. Malty, James Vlasblom, Mohan Babu, Sadhna Phanse, Larissa Hoell, Matthew Jessulat, Zoran Minic, Eleonora Lamantea, Alla Gagarinova, Barbara Garavaglia, Mohamed Taha Moutaoufik, Maria Gagarinova, Shahreen Amin, Florian Goebels, Kei Murayama, Kirsten Broderick, Gary D. Bader, Gabriel Musso
Publikováno v:
iScience, Vol 19, Iss, Pp 1114-1132 (2019)
iScience
iScience
Summary Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f9d4f6ef65c96ea044d1c087ba5a27
https://hdl.handle.net/10281/417319
https://hdl.handle.net/10281/417319
Autor:
Gabriel Musso, James Vlasblom, Ashwani Kumar, Cedoljub Bundalovic-Torma, Mohsen Hooshyar, Sadhna Phanse, Alexander F. Yakunin, Viktor Deineko, John Parkinson, Zoran Minic, Omar Wagih, Ashkan Golshani, Patrick Aloy, Roberto Mosca, Natalia Beloglazova, Mohan Babu, Andrew Emili, Sofia Lemak, Alla Gagarinova
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 648-661 (2016)
As antibiotic resistance is increasingly becoming a public health concern, an improved understanding of the bacterial DNA damage response (DDR), which is commonly targeted by antibiotics, could be of tremendous therapeutic value. Although the genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae98591997b9aded294a0f5c638ff1e8
http://www.sciencedirect.com/science/article/pii/S2211124715015016
http://www.sciencedirect.com/science/article/pii/S2211124715015016
Autor:
J. Harry Caufield, Christine Chieh-Lin Lai, Cedoljub Bundalovic-Torma, Majida El Bakkouri, Mohsen Hooshyar, Sun Young Kim, Charles Calmettes, Yogee Pandya, Zhongge Zhang, Hongbo Guo, Sessandra V. Rajagopala, Dan Burnside, Zoran Minic, Milton H. Saier, Erik Holtzapple, Trevor F. Moraes, Megha Shah, Mohan Babu, Åke Västermark, Irina A. Rodionova, Sadhna Phanse, Peter Uetz, Hiroyuki Aoki, Ashkan Golshani, Qingzhou Zhang, John Parkinson, Viktor Deineko, Stefan Wuchty, Andrew Emili, James Vlasblom, Alla Gagarinova, Jack Greenblatt, Yogesh Hooda, Jitender Mehla, Yue Jiang, Oxana Pogoutse, Olga Kagan, Ashwani Kumar
Publikováno v:
Nature Biotechnology
Nature Biotechnology, Nature Publishing Group, 2018, 36 (1), pp.103-112. ⟨10.1038/nbt.4024⟩
Nature Biotechnology, Nature Publishing Group, 2018, 36 (1), pp.103-112. ⟨10.1038/nbt.4024⟩
International audience; Bacterial cell envelope protein (CEP) complexes mediate a range of processes, including membrane assembly, antibiotic resistance and metabolic coordination. However, only limited characterization of relevant macromolecules has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245f97b83be64faa1e444fadeb6c2a29
https://hal-riip.archives-ouvertes.fr/pasteur-01688877
https://hal-riip.archives-ouvertes.fr/pasteur-01688877
Autor:
Florian Goebels, Ken Nakamura, Zoran Minic, Barbara Garavaglia, Tiziana Alberio, John Parkinson, Sandy Kassir, Leonard J. Foster, Bhanu Prasad, Mohan Babu, Vishaldeep Sidhu, Nichollas E. Scott, Hiroyuki Aoki, Haiyuan Yu, Viktor Deineko, Qingzhou Zhang, Michael J. Meyer, James Vlasblom, Matthew Jessulat, Sadhna Phanse, Zhuoran Wu, Ashwani Kumar, Ramy H. Malty, Gary D. Bader, Gabriel Musso, Shahreen Amin, Xuejian Xiong, Hosam Abou-tok
Publikováno v:
Cell systems, vol 5, iss 6
Mitochondrial protein (MP) dysfunction has been linked to neurodegenerative disorders (NDs); however, the discovery of the molecular mechanisms underlying NDs has been impeded by the limited characterization of interactions governing MP function. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7da6f082050938157578f206339844
http://hdl.handle.net/11383/2069047
http://hdl.handle.net/11383/2069047