Native Mass Spectrometry Reveals Binding Interactions of SARS-CoV-2 PLpro with Inhibitors and Cellular Targets.

Autor: James VK; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Godula RN; Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas 78712, United States., Perez JM; Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas 78712, United States., Beckham JT; Freshman Research Initiative, The University of Texas at Austin, Austin, Texas 78712, United States., Butalewicz JP; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Sipe SN; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Huibregtse JM; Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas 78712, United States., Brodbelt JS; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2024 Oct 11; Vol. 10 (10), pp. 3597-3606. Date of Electronic Publication: 2024 Sep 20.

Hydrophilic Interaction Chromatography Coupled to Ultraviolet Photodissociation Affords Identification, Localization, and Relative Quantitation of Glycans on Intact Glycoproteins.

Autor: James VK; Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States., van der Zon AAM; van 't Hoff Institute for Molecular Science, University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands.; Centre of Analytical Sciences Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands., Escobar EE; Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States., Dunham SD; Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States., Gargano AFG; van 't Hoff Institute for Molecular Science, University of Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands.; Centre of Analytical Sciences Amsterdam, Science Park 904, Amsterdam 1098 XH, The Netherlands., Brodbelt JS; Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.

Publikováno v: Journal of proteome research [J Proteome Res] 2024 Oct 04; Vol. 23 (10), pp. 4684-4693. Date of Electronic Publication: 2024 Sep 23.

Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 gangliosidosis.

Autor: Allende ML; Genetics of Development and Disease Section, Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Lee YT; Genetics of Development and Disease Section, Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Byrnes C; Genetics of Development and Disease Section, Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Li C; Genetics of Development and Disease Section, Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Tuymetova G; Genetics of Development and Disease Section, Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Bakir JY; Genetics of Development and Disease Section, Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Nicoli ER; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., James VK; Department of Chemistry, University of Texas at Austin, Austin, TX, USA., Brodbelt JS; Department of Chemistry, University of Texas at Austin, Austin, TX, USA., Tifft CJ; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: cynthiat@mail.nih.gov., Proia RL; Genetics of Development and Disease Section, Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address: proia@nih.gov.

Publikováno v: Journal of lipid research [J Lipid Res] 2023 Dec; Vol. 64 (12), pp. 100463. Date of Electronic Publication: 2023 Oct 21.

Advancing Orbitrap Measurements of Collision Cross Sections to Multiple Species for Broad Applications.

Autor: James VK; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Sanders JD; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Aizikov K; Thermo Fisher Scientific, Bremen 28199, Germany., Fort KL; Thermo Fisher Scientific, Bremen 28199, Germany., Grinfeld D; Thermo Fisher Scientific, Bremen 28199, Germany., Makarov A; Thermo Fisher Scientific, Bremen 28199, Germany.; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht 3584, The Netherlands., Brodbelt JS; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2022 Nov 15; Vol. 94 (45), pp. 15613-15620. Date of Electronic Publication: 2022 Nov 03.

Enhanced Ion Mobility Separation and Characterization of Isomeric Phosphatidylcholines Using Absorption Mode Fourier Transform Multiplexing and Ultraviolet Photodissociation Mass Spectrometry.

Autor: Sanders JD; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Shields SW; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Escobar EE; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Lanzillotti MB; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Butalewicz JP; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., James VK; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Blevins MS; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Sipe SN; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States., Brodbelt JS; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2022 Mar 15; Vol. 94 (10), pp. 4252-4259. Date of Electronic Publication: 2022 Mar 03.