Zobrazeno 1 - 10
of 54
pro vyhledávání: '"James V. Staros"'
Publikováno v:
Receptor Phosphorylation ISBN: 9781351076241
Receptor Phosphorylation
Receptor Phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37f4e022a989fb2a0922a7379d9a0009
https://doi.org/10.1201/9781351076241-10
https://doi.org/10.1201/9781351076241-10
Publikováno v:
International Journal of Peptide and Protein Research. 47:219-226
Epidermal growth factor (EGF) stimulates cellular mitogenesis by binding to and activating its membrane-associated receptor. An important component of signal transduction by the activated receptor is the stimulation of an intrinsic tyrosyl residue-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51ff4c1e1cbc5c1f698831419cdf65f
https://doi.org/10.1111/j.1399-3011.1996.tb01348.x
https://doi.org/10.1111/j.1399-3011.1996.tb01348.x
Autor:
A.H. Beth, Kristin B. Whitson, Austin J. McCoy, Monica Red-Brewer, Francesca Walker, James V. Staros, Terrance Grant Johns, Stefanie R. Whitson, Angela A. Vitali
Publikováno v:
Biochemistry. 44:14920-14931
We have investigated functional effects of glycosylation at N(579) of the epidermal growth factor receptor (EGFR). Our previous study showed that the population of cell-surface expressed EGFRs in A431 cells, a human epidermoid carcinoma cell line, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400bd8cde6167ec63930ea50ff2ba68b
https://doi.org/10.1021/bi050751j
https://doi.org/10.1021/bi050751j
Publikováno v:
Journal of Receptors and Signal Transduction. 22:357-371
We have developed a system for extending stopped-flow analysis to the kinetics of ligand capture and release by cell surface receptors in living cells. While most mammalian cell lines cannot survive the shear forces associated with turbulent, stopped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50f3ca40325db2cafca43518d21f997
https://doi.org/10.1081/rrs-120014607
https://doi.org/10.1081/rrs-120014607
Autor:
James V. Staros, John C. Wilkinson
Publikováno v:
Biochemistry. 41:8-14
We have extended the use of stopped-flow mixing and fluorescence anisotropy detection to investigate in real-time the effects of ErbB2 coexpression on the kinetic interactions of epidermal growth factor (EGF) with the EGF receptor. Using stable 32D-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8b8d6243d149ada3fd5ceedf572a52
https://doi.org/10.1021/bi015839l
https://doi.org/10.1021/bi015839l
Publikováno v:
Biochemistry. 40:6142-6154
In ligand binding studies, ligand depletion often limits the accuracy of the results obtained. This problem is approached by employing the simple observation that as the concentration of receptor in the assay is reduced, ligand depletion is also redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6194e80906f6e011be3f49cfc884e3b1
https://doi.org/10.1021/bi002817a
https://doi.org/10.1021/bi002817a
Autor:
Randall L. Woltjer, James V. Staros
Publikováno v:
Biochemistry. 36:9911-9916
Earlier reports have indicated that epidermal growth factor (EGF) receptor autophosphorylation, thought to be a key step in receptor transmembrane signaling, can be inactivated with the relatively sulfhydryl-specific reagent N-ethylmaleimide (NEM); h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b26340b27a4771af53a415e2cd21e0
https://doi.org/10.1021/bi963007v
https://doi.org/10.1021/bi963007v
Publikováno v:
Journal of Biological Chemistry. 271:19656-19659
A triple mutant of murine epidermal growth factor (mEGF), N1Q/H22Y/R45K-mEGF, was constructed by site-directed mutagenesis, expressed, purified, and characterized for use in an affinity cross-linking study to identify aminoacyl residues of the EGF re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f86b13cd34b6e8c3af7074959d4948
https://doi.org/10.1074/jbc.271.33.19656
https://doi.org/10.1074/jbc.271.33.19656
Autor:
Dennis L. Rousseau, Baiyang Wang, Ray Wu, Albert H. Beth, Cheryl A. Guyer, James V. Staros, Ioannis A. Papayannopoulos, Barbara Mroczkowski
Publikováno v:
Biochemistry. 32:7893-7903
In this report we describe the production of a [Lys3,Tyr22] murine epidermal growth factor (mEGF) mutant for spin-labeling with bis(sulfo-N-succinimidyl)-[15N,2H16]doxyl-2-spiro-4'-pimelate ([15N,2H16]BSSDP) in order to study the rotational dynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4256848a625a3a022eea8dac3eeca28f
https://doi.org/10.1021/bi00082a009
https://doi.org/10.1021/bi00082a009
Autor:
Ioannis A. Papayannopoulos, Lee Anne Faulkner-O'Brien, P. S. R. Anjaneyulu, Albert H. Beth, James V. Staros
Publikováno v:
Biochemistry. 30:8976-8985
We prepared, purified, and characterized derivatives of epidermal growth factor (EGF) having a nitroxide spin-label attached covalently at the amino terminus. Characterization of these derivatives with regard to the positions of attachment of the spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8954b38a47eb8af606c4fe4b5084c1f
https://doi.org/10.1021/bi00101a010
https://doi.org/10.1021/bi00101a010