Zobrazeno 1 - 6
of 6
pro vyhledávání: '"James V. Oakley"'
Autor:
James V. Oakley, Benito F. Buksh, David F. Fernández, Daniel G. Oblinsky, Ciaran P. Seath, Jacob B. Geri, Gregory D. Scholes, David W. C. MacMillan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(32)
The elucidation of protein interaction networks is critical to understanding fundamental biology as well as developing new therapeutics. Proximity labeling platforms (PLPs) are state-of-the-art technologies that enable the discovery and delineation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc834b8193e8b25bff5af0bb2f397ae
https://pubmed.ncbi.nlm.nih.gov/35914173
https://pubmed.ncbi.nlm.nih.gov/35914173
Autor:
Benito F. Buksh, Ian B. Perry, Edna Mao, Holt A. Sakai, Amy Y. Chan, Nicholas L. Reed, Agustin Millet, Lucas I. Frye, James V. Oakley, Beryl X. Li, David W. C. MacMillan, Grant A. Edwards, Ciaran P. Seath, Noah B. Bissonnette, Marissa N. Lavagnino, Olivia L. Garry, Yufan Liang
Publikováno v:
Chemical Reviews. 122:1485-1542
The merger of photoredox catalysis with transition metal catalysis, termed metallaphotoredox catalysis, has become a mainstay in synthetic methodology over the past decade. Metallaphotoredox catalysis has combined the unparalleled capacity of transit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87089ce0d0123bef7d3644e6fadfce16
https://doi.org/10.1021/acs.chemrev.1c00383
https://doi.org/10.1021/acs.chemrev.1c00383
Autor:
Benito F. Buksh, Steve D. Knutson, James V. Oakley, Noah B. Bissonnette, Daniel G. Oblinsky, Michael P. Schwoerer, Ciaran P. Seath, Jacob B. Geri, Frances P. Rodriguez-Rivera, Dann L. Parker, Gregory D. Scholes, Alexander Ploss, David W. C. MacMillan
Publikováno v:
J Am Chem Soc
Modern proximity labeling techniques have enabled significant advances in understanding biomolecular interactions. However, current tools primarily utilize activation modes that are incompatible with complex biological environments, limiting our abil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150310636971e2b294144d6b9e3ac99d
https://pubmed.ncbi.nlm.nih.gov/35363468
https://pubmed.ncbi.nlm.nih.gov/35363468
Autor:
Cory H. White, Adam G. Schwaid, Keun Ah Ryu, Olugbeminiyi O. Fadeyi, Beryl X. Li, David W. C. MacMillan, Frances P. Rodriguez-Rivera, James V. Oakley, Dann L. Parker, Jacob B. Geri, Paul Tawa, Tamara Reyes-Robles, Rob C. Oslund, Aaron D. Trowbridge, Barbara E. Dul, Ciaran P. Seath
Publikováno v:
bioRxiv
BioRxiv
BioRxiv
The identification of cellular targets that can be exploited for therapeutic benefit, broadly known as target ID, remains a fundamental goal in drug discovery. In recent years, the application of new chemical and biological technologies that accelera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e7fb28b863a109210656d766c921a8
https://doi.org/10.1101/2021.08.02.454797
https://doi.org/10.1101/2021.08.02.454797
Autor:
Stephanie E. Cain, Aloha L. Prince, Amanda K. Melanese, Tyler J. Stanley, Araceli A. Alvarez, James V. Oakley, Kate A. Jesse, Anna G. Wenzel, Robert G. Iafe
Publikováno v:
European Journal of Organic Chemistry. 2019:7063-7066
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d89629e8276b748c226ac88674a4efab
https://doi.org/10.1002/ejoc.201901082
https://doi.org/10.1002/ejoc.201901082
Autor:
Erik C. Hett, David W. C. MacMillan, James V. Oakley, Cory H. White, Tao Wang, Dann L. Parker, Tamara Reyes-Robles, Olugbeminiyi O. Fadeyi, Jacob B. Geri, Frances P. Rodriguez-Rivera, Stefan J. McCarver, Rob C. Oslund
Publikováno v:
Science (New York, N.Y.). 367(6482)
Pinpointing proteins To develop drugs that target a specific cell surface protein, it's helpful to know which other proteins reside in its vicinity. Geri et al. report a light-triggered labeling technique that improves the spatial resolution for this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcccc7c3d0f0493d2935a89122ef9777
https://pubmed.ncbi.nlm.nih.gov/32169879
https://pubmed.ncbi.nlm.nih.gov/32169879