Zobrazeno 1 - 10
of 294
pro vyhledávání: '"James V Jester"'
Autor:
Vindhya Koppaka, Ying Chen, Gaurav Mehta, David J Orlicky, David C Thompson, James V Jester, Vasilis Vasiliou
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146433 (2016)
Aldehyde dehydrogenase 1A1 (ALDH1A1) and ALDH3A1 are corneal crystallins. They protect inner ocular tissues from ultraviolet radiation (UVR)-induced oxidative damage through catalytic and non-catalytic mechanisms. Additionally, ALDH3A1 has been postu
Externí odkaz:
https://doaj.org/article/c2762e4783354e6abe653638a166c967
Autor:
Daniel C Mendez, Alexander E Stover, Anthony D Rangel, David J Brick, Hubert E Nethercott, Marissa A Torres, Omar Khalid, Andrew MS Wong, Jonathan D Cooper, James V Jester, Edwin S Monuki, Cian McGuire, Steven Q Le, Shih-hsin Kan, Patricia I Dickson, Philip H Schwartz
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Mucopolysaccharidosis type I (MPS I) is an inherited α-L-iduronidase (IDUA, I) deficiency in which glycosaminoglycan (GAG) accumulation causes progressive multisystem organ dysfunction, neurological impairment, and death. Current MPS I mouse model
Externí odkaz:
https://doaj.org/article/ec547ae9e4934826868fcc0d024e618e
Autor:
Osamu Yamanaka, Yong Yuan, Vivien Jane Coulson-Thomas, Tarsis Ferreira Gesteira, Mindy K Call, Yujin Zhang, Jianhua Zhang, Shao-Hsuan Chang, Changchun Xie, Chia-Yang Liu, Shizuya Saika, James V Jester, Winston W-Y Kao
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82730 (2013)
Lumican (Lum), a small leucine-rich proteoglycan (SLRP) family member, has multiple matricellular functions both as an extracellular matrix component and as a matrikine regulating cell proliferation, gene expression and wound healing. To date, no cel
Externí odkaz:
https://doaj.org/article/20cab25e41e347ba99c49991e93944cf
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53245 (2012)
Current immunofluorescence protocols are limited as they do not provide reliable antibody staining within large tissue volumes (mm(3)) and cannot localise and quantify multiple antigens or cell populations in the same tissue at high resolution. To ad
Externí odkaz:
https://doaj.org/article/6cbea14494ba4eaf811055b6b44a5638
Autor:
Hongshan Liu, Jianhua Zhang, Chia-Yang Liu, I-Jong Wang, Martin Sieber, John Chang, James V Jester, Winston W Y Kao
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10707 (2010)
Keratoplasty is the most effective treatment for corneal blindness, but suboptimal medical conditions and lack of qualified medical personnel and donated cornea often prevent the performance of corneal transplantation in developing countries. Our stu
Externí odkaz:
https://doaj.org/article/0bf18526b74b4683844addd5429e43c4
Autor:
Jerry R. Paugh, Tiffany Nguyen, Alan Sasai, Elaine Chen, Melinda Thomas De Jesus, Justin Kwan, Andrew Loc Nguyen, Marjan Farid, Sumit Garg, James V. Jester
Publikováno v:
Journal of Ophthalmology, Vol 2022 (2022)
Objectives. To determine the efficacy of widely available subtype clinical tests to characterize evaporative dry eye disease (EDED) related to meibomian gland dysfunction (MGD) compared to normal and to validate those clinical cut points in an indepe
Externí odkaz:
https://doaj.org/article/7685251cf85f4e648a66d3a7e979ac28
Publikováno v:
The Ocular Surface. 25:49-54
We have previously used Immuno Tomography (IT) to identify label-retaining stem cell populations in the cornea and meibomian gland. While this method provides the unique ability to quantify stem cell populations comprised of 1-4 cells, the number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07e5354269cc9620d266165657422f4
https://doi.org/10.1016/j.jtos.2022.04.008
https://doi.org/10.1016/j.jtos.2022.04.008
Autor:
Fangyuna Gao, James V. Jester, Donald J. Brown, Yilu Xie, Chang Rae Rho, Sun Woong Kim, Jinseor Kim, Dorota Skowronska-Krawczyk, Shelley Lane
Publikováno v:
The Ocular Surface. 23:60-70
Purpose Previously, we showed that Acyl-CoA wax-alcohol acyltransferase 2 (AWAT2), an essential enzyme required for meibum wax ester synthesis, was not expressed by immortalized human meibomian gland epithelial cells (hMGEC) in culture. To begin to u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d28feead831f4dc6a293ecd6e1d0bd
https://doi.org/10.1016/j.jtos.2021.11.010
https://doi.org/10.1016/j.jtos.2021.11.010
Autor:
James W. Spurlin, James V. Jester, Elena Koudouna, Peter Y. Lwigale, Anna Babushkina, Andrew J. Quantock
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Wound healing is characterized by cell and extracellular matrix changes mediating cell migration, fibrosis, remodeling and regeneration. We previously demonstrated that chick fetal wound healing shows a regenerative phenotype regarding the cellular a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec904ffc4eeba5fd1ac36ad73ff70ef9
http://link.springer.com/article/10.1038/s41598-020-70658-y
http://link.springer.com/article/10.1038/s41598-020-70658-y
Publikováno v:
The ocular surface. 26
Recent studies have shown that two-dimensional (2D) culture of primary rabbit and immortalized human meibomian gland epithelial cells (iHMGEC) do not recapitulate normal meibocyte differentiation and fail to express critical enzymes necessary for syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dd6cccfca8725cc06718a7b1dc6778
https://pubmed.ncbi.nlm.nih.gov/36341959
https://pubmed.ncbi.nlm.nih.gov/36341959