Zobrazeno 1 - 10
of 170
pro vyhledávání: '"James U, Bowie"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Ethanol is a widely available carbon compound that can be increasingly produced with a net negative carbon balance. Carbon-negative ethanol might therefore provide a feedstock for building a wider range of sustainable chemicals. Here we show
Externí odkaz:
https://doaj.org/article/9c8fbdbf61ac4fd3bc651470fe03f98b
Autor:
Hongjiang Liu, James U. Bowie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract It is now possible to efficiently fix flue gas CO/CO2 into ethanol using acetogens, thereby making carbon negative ethanol. While the ethanol could be burned as a fuel, returning the CO2 to the atmosphere, it might also be possible to use th
Externí odkaz:
https://doaj.org/article/b7187d1dcdff4a3e914f8a1b4e8e652a
Autor:
Saken Sherkhanov, Tyler P. Korman, Sum Chan, Salem Faham, Hongjiang Liu, Michael R. Sawaya, Wan-Ting Hsu, Ellee Vikram, Tiffany Cheng, James U. Bowie
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
A cell free or synthetic biochemistry approach offers a way to circumvent the many constraints of living cells. Here, the authors demonstrate, via enzyme and process enhancements, the production of isobutanol with the metrics exceeding highly develop
Externí odkaz:
https://doaj.org/article/6d928504ca27437ea5b6a0df6826c323
Autor:
Meaghan A. Valliere, Tyler P. Korman, Nicholas B. Woodall, Gregory A. Khitrov, Robert E. Taylor, David Baker, James U. Bowie
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Producing individual cannabinoids by metabolically engineered microbes has proven challenging. Here, the authors develop a cell-free enzymatic prenylating system to generate isoprenyl pyrophosphate substrates directly from glucose and produce both co
Externí odkaz:
https://doaj.org/article/91846144fed24fbd93ae5a96ab7c927a
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Terpenes are bioactive natural products derived from plants with several commercial applications. Here, the authors engineer a cell-free system composed of 27 enzymes that convert glucose into terpenes, highlighting the potential of synthetic biochem
Externí odkaz:
https://doaj.org/article/bb8ace10bdcb41a5a7a1b989f4dffc78
Autor:
Meaghan A. Valliere, Tyler P. Korman, Nicholas B. Woodall, Gregory A. Khitrov, Robert E. Taylor, David Baker, James U. Bowie
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
In the original version of this Article, the genotype of the M30 mutant presented in Fig. 3b was given incorrectly as Y288V/A232S, and the M31 mutant was given incorrectly as M1/A232S. The correct genotype of the M30 mutant is Y288A/A232S and for M31
Externí odkaz:
https://doaj.org/article/6f029ec8655a4654b94ece5ae0d798c1
Publikováno v:
Nature Chemical Biology. 16:1427-1433
Moving cannabinoid production away from the vagaries of plant extraction and into engineered microbes could provide a consistent, purer, cheaper and environmentally benign source of these important therapeutic molecules, but microbial production face
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b28a8e60a650de70e6b3412845590074
https://doi.org/10.1038/s41589-020-0631-9
https://doi.org/10.1038/s41589-020-0631-9
Autor:
Hongjiang Liu, Meaghan Valliere, James U. Bowie, Paul H. Opgenorth, Saken Sherkhanov, Tyler P. Korman
Publikováno v:
Trends in Biotechnology. 38:766-778
Metabolic engineering efforts that harness living organisms to produce natural products and other useful chemicals face inherent difficulties because the maintenance of life processes often runs counter to our desire to maximize important production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ef0d7a3187db424c88b4aeb8b4f1cf
https://doi.org/10.1016/j.tibtech.2019.12.024
https://doi.org/10.1016/j.tibtech.2019.12.024
Autor:
Karolina Corin, James U Bowie
Publikováno v:
EMBO Rep
Protein folding is a fundamental process of life with important implications throughout biology. Indeed, tens of thousands of mutations have been associated with diseases, and most of these mutations are believed to affect protein folding rather than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ba5bb2aee6316486b9fc8cf9154708
https://europepmc.org/articles/PMC8892262/
https://europepmc.org/articles/PMC8892262/
Autor:
Mizuki Aoki, Jeffrey Vinokur, Kento Motoyama, Rino Ishikawa, Michael Collazo, Duilio Cascio, Michael R. Sawaya, Tomokazu Ito, James U. Bowie, Hisashi Hemmi
Publikováno v:
Journal of Biological Chemistry. 298:102111
Mevalonate 3,5-bisphosphate decarboxylase is involved in the recently discovered Thermoplasma-type mevalonate pathway. The enzyme catalyzes the elimination of the 3-phosphate group from mevalonate 3,5-bisphosphate as well as concomitant decarboxylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6e2feb16da3a67b175661d6abf0b45
https://doi.org/10.1016/j.jbc.2022.102111
https://doi.org/10.1016/j.jbc.2022.102111