Zobrazeno 1 - 8
of 8
pro vyhledávání: '"James Trevor Oswald"'
Autor:
Hai Huang, Xiangrong Song, Xiaorong Yang, Huili Li, Jun Zeng, James Trevor Oswald, Xingchen Peng, Hansi Lu, Yongmei Liu, Ji-Yan Liu, Chaohui Jin
Publikováno v:
Nano Research. 13:3105-3109
Ocular drug delivery remains a significant challenge that is limited by poor corneal retention and permeation, resulting in low ocular bioavailability (< 5%). Worse still, the most convenient and safe route of ocular drug administration, topical admi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef9e9993e444601930d3b8f190f3ad0e
https://doi.org/10.1007/s12274-020-2980-9
https://doi.org/10.1007/s12274-020-2980-9
Autor:
Erin L Oswald, Haritosh Patel, Ninweh N Jeorje, James Trevor Oswald, Daid A. Khan, Shirley Tang, Hossein Golzar
Publikováno v:
Current Pharmaceutical Design. 26:2057-2071
The innate abilities of cancer stem cells (CSCs), such as multi-drug resistance, drug efflux, quiescence and ionizing radiation tolerance, protect them from most traditional chemotherapeutics. As a result, this small subpopulation of persistent cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875ddca101ea87d8915462a9ebd683f3
https://doi.org/10.2174/1381612826666200406084900
https://doi.org/10.2174/1381612826666200406084900
Autor:
Li Sheng, Daxin Pang, Haisi Dong, Hongsheng Ouyang, Ang Su, Junqiu Liu, Dongmei Lv, Zhiping Xia, Jinsong Liu, Huping Jiao, Jianwei Dong, Mingjun Zhang, James Trevor Oswald
Publikováno v:
ACS Applied Materials & Interfaces. 11:22164-22170
Infectious diseases caused by pathogenic bacteria (such as sepsis and meningitis) seriously threaten public health; therefore, rapid and accurate identification of the target bacteria is urgently needed to prevent and treat bacterial infections. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aeb5ab4f3557f20d0beb92d933f4ad9
https://doi.org/10.1021/acsami.9b05666
https://doi.org/10.1021/acsami.9b05666
Autor:
Gha Young Lee, James Trevor Oswald, Omid C. Farokhzad, Jessalyn M. Ubellacker, Jinjun Shi, Kun Zhou, Robert Langer, Mi Kyung Yu, Philip W. Kantoff, Michael Lim, Meshkat Dinarvand, Mohammad Ariful Islam, Morteza Mahmoudi, Wuji Cao, Wei Tao, Yingjie Xu, Bruce R. Zetter, Harshal Zope, Daniel Aum
Publikováno v:
Nature biomedical engineering
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a well-characterized tumour-suppressor gene that is lost or mutated in about half of metastatic castration-resistant prostate cancers and in many other human cancers. The restoration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61f755b179f14897122f74a1bd8199c
https://doi.org/10.1038/s41551-018-0284-0
https://doi.org/10.1038/s41551-018-0284-0
Publikováno v:
Chemical Research in Chinese Universities. 34:428-433
Human growth hormone(hGH), a classic therapeutic protein, which promotes growth and wound healing, is released from the pituitary gland. As a protein drug, its short half-life is its main barrier to therapeutic efficacy. Various strategies have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c007c5b10b830153d330f82ace8574e6
https://doi.org/10.1007/s40242-018-8023-3
https://doi.org/10.1007/s40242-018-8023-3
Publikováno v:
Current medicinal chemistry. 27(18)
As one of the leading and most important metal-based drugs, platinum-based pharmaceuticals are widely used in the treatment of solid malignancies. Despite significant side effects and acquired drug resistance have limited their clinical applications,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd724ae20a72468da161bceee1d9e21
https://pubmed.ncbi.nlm.nih.gov/30394206
https://pubmed.ncbi.nlm.nih.gov/30394206
Autor:
Yongmei Liu, Quansheng Jin, Huili Li, Yang Zhou, Chunling Jiang, James Trevor Oswald, Zhaohui Jin, Lingjing Huang, Xiangrong Song, Fazhan Wang, Jinhui Wu
Publikováno v:
International journal of pharmaceutics. 553(1-2)
The aim of this study is to investigate the potential of D-alpha-tocopheryl poly (ethylene glycol 1000) succinate (TPGS) modified nanoliposomes as an ophthalmic delivery system of brinzolamide (Brz) for glaucoma treatment. The Brz loaded nanoliposome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675eb07cb61c4734183744d1ffc62417
https://pubmed.ncbi.nlm.nih.gov/30316795
https://pubmed.ncbi.nlm.nih.gov/30316795
Autor:
James Trevor Oswald, Mohammad Ariful Islam, Morteza Mahmoudi, Omid C. Farokhzad, Jessalyn M. Ubellacker, Gha Young Lee, Kun Zhou, Jinjun Shi, Wuji Cao, Robert Langer, Meshkat Dinarvand, Wei Tao, Bruce R. Zetter, Harshal Zope, Daniel Aum, Michael Lim, Mi Kyung Yu, Yingjie Xu, Philip W. Kantoff
Publikováno v:
Nature Biomedical Engineering. 2:968-968
The authors wish to add the following sentence into the 'Competing interests' section of this Article: "P.W.K. has investment interest in Context Therapeutics LLC, DRGT, Placon, Seer Biosciences and Tarveda Therapeutics, is a company board member for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442ccbf2901821cd62091c946b44ca24
https://doi.org/10.1038/s41551-018-0331-x
https://doi.org/10.1038/s41551-018-0331-x