Zobrazeno 1 - 10
of 12
pro vyhledávání: '"James Thurmond"'
Autor:
Robert Yehl, James Thurmond
Publikováno v:
International Journal of Organization Theory and Behavior. 20:269-310
For a good part of the U.S. system of federalism municipal incorporation has been the formal structure for local communities. Over the last 60 years there has been a shift in this structure to special district government. The Woodlands, Texas present
Autor:
Frederick B. Rogers, James Thurmond, Katherine Bupp, Brian W. Gross, Lisa Estrella, Katelyn J. Rittenhouse, Amelia Rogers, John C. Lee, Michael A. Horst
Publikováno v:
Injury. 46:854-858
Evidence-based guidelines for the care of severe traumatic brain injury have been available from the Brain Trauma Foundation (BTF) since 1995. A total of 15 recommendations compose the current guidelines. Although each individual guideline has been v
Publikováno v:
Nucleic Acids Research
Hemorrhagic fever viruses (HFVs) are a diverse set of over 80 viral species, found in 10 different genera comprising five different families: arena-, bunya-, flavi-, filo- and togaviridae. All these viruses are highly variable and evolve rapidly, mak
Autor:
James Thurmond
Publikováno v:
State and Local Government Review. 42:226-234
Does small-city management experience (100,000 population), and does it help them to keep the large-city jobs? The answers to these questions are important for city managers planning a move to a larger city and for young professionals planning a care
Genotype 1 and global hepatitis C T-cell vaccines designed to optimize coverage of genetic diversity
Autor:
Bette T. Korber, Paul W. Fenimore, Georg M. Lauer, Will Fischer, James Thurmond, Carla Kuiken, Karina Yusim, Hyejin Yoon
Publikováno v:
Journal of General Virology. 91:1194-1206
Immunological control of hepatitis C virus (HCV) is possible and is probably mediated by host T-cell responses, but the genetic diversity of the virus poses a major challenge to vaccine development. We considered monovalent and polyvalent candidates
Publikováno v:
Nucleic Acids Research
The hepatitis C virus (HCV) is a significant public health threat worldwide. The virus is highly variable and evolves rapidly, making it an elusive target for the immune system and for vaccine and drug design. Presently, approximately 50 000 HCV sequ
Autor:
James Thurmond, Lee Philip Reilly, Peter T. Hraber, Karina Yusim, Robert W Leach, Carla Kuiken
Publikováno v:
Antiviral Chemistry and Chemotherapy. 18:113-123
The hepatitis C virus (HCV) resource at Los Alamos (hcv.lanl.gov) provides access to multiple databases: one containing annotated sequences and the other a repository of immunogenic epitopes. They are derived from databases originally developed for H
Publikováno v:
Neurosurgery. 55:E1236-E1239
OBJECTIVE AND IMPORTANCE: Sciatic neuropathy rarely presents in nonpenetrating trauma because of protection of the nerve by the pelvis, the gluteal muscles, and the tissues in the posterior thigh. We present the case of a patient who fell and subsequ
Autor:
James Thurmond, Brian T. Foley, Hyejin Yoon, Michael W. Parker, Mary Kate Hart, Karina Yusim, Will Fischer, John M. Dye, Carla Kuiken, Russell R. Bakken, Paul W. Fenimore, Bette T. Korber, Majidat A. Muhammad
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e44769 (2012)
PLoS ONE, Vol 7, Iss 10, p e44769 (2012)
We report the rational design and in vivo testing of mosaic proteins for a polyvalent pan-filoviral vaccine using a computational strategy designed for the Human Immunodeficiency Virus type 1 (HIV-1) but also appropriate for Hepatitis C virus (HCV) a
Autor:
James Thurmond, James Theiler, Karina Yusim, Hyejin Yoon, Tanmoy Bhattacharya, Bette T. Korber, Simon Perkins, Will Fischer, Carla Kuiken
Publikováno v:
Bioinformatics (Oxford, England). 24(14)
Summary: We present a suite of on-line tools to design candidate vaccine proteins, and to assess antigen potential, using coverage of k-mers (as proxies for potential T-cell epitopes) as a metric. The vaccine design tool uses the recently published