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pro vyhledávání: '"James Thomas Matthews"'
Publikováno v:
Journal of virology. 64(10)
The analysis of the deduced amino acid sequence of the herpes simplex virus type 1 (HSV-1) DNA polymerase reported here suggests that the polymerase structure consists of domains carrying separate biological functions. The HSV-1 enzyme is known to po
Publikováno v:
Virus genes. 3(4)
Synthetic peptides corresponding to amino acid sequences present in the herpes simplex virus type-1 (HSV-1) DNA polymerase (pol) were used to raise polyclonal rabbit antisera. The three peptides described in detail in this report were among seven seq
Autor:
M L Haffey, James Thomas Matthews, Terry Bj, R D Carroll, C W Cianci, J T Stevens, M. E. Hagen
Publikováno v:
Antiviral Research. 15:109
Publikováno v:
Journal of virology. 63(11)
A mutation (asparagine 815 to serine 815) was introduced into the herpes simplex virus type 1 (HSV-1) DNA polymerase (pol). The HSV-1 pol enzyme in lysates of Saccharomyces cerevisiae cells expressing the mutant protein showed increased resistance to