Výsledky vyhledávání - "James Tarabokija"

Akademický článek

Preparation and Characterization of Spray-Dried Hybrid Nanocrystal–Amorphous Solid Dispersions (HyNASDs) for Supersaturation Enhancement of a Slowly Crystallizing Drug

Autor: Mahbubur Rahman, Keanu Radgman, James Tarabokija, Stephanie Ahmad, Ecevit Bilgili

Publikováno v: Nanomaterials, Vol 13, Iss 17, p 2419 (2023)

We prepared hybrid nanocrystal–amorphous solid dispersions (HyNASDs) to examine their supersaturation capability in the release of a poorly soluble drug, itraconazole (ITZ), a slow crystallizer during dissolution. The HyNASD formulations included a

Externí odkaz: https://doaj.org/article/878d2e02f4ad4a80aae141e4ffe5614b

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Akademický článek

Spray-Dried Amorphous Solid Dispersions of Griseofulvin in HPC/Soluplus/SDS: Elucidating the Multifaceted Impact of SDS as a Minor Component

Autor: Mahbubur Rahman, Stephanie Ahmad, James Tarabokija, Nathaniel Parker, Ecevit Bilgili

Publikováno v: Pharmaceutics, Vol 12, Iss 3, p 197 (2020)

This study aimed to elucidate the impact of a common anionic surfactant, sodium dodecyl sulfate (SDS), along with hydroxypropyl cellulose (HPC) and Soluplus (Sol) on the release of griseofulvin (GF), a poorly soluble drug, from amorphous solid disper

Externí odkaz: https://doaj.org/article/0573ab219b114f0a90f08aa4560946bc

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Roles of surfactant and polymer in drug release from spray-dried hybrid nanocrystal-amorphous solid dispersions (HyNASDs)

Autor: James Tarabokija, Stephanie Ahmad, Mahbubur Rahman, Ecevit Bilgili

Publikováno v: Powder Technology. 361:663-678

We prepared hybrid nanocrystal–amorphous solid dispersions (HyNASDs) to enhance the dissolution of a poorly soluble drug, griseofulvin (GF), and elucidated the roles of a surfactant, sodium dodecyl sulfate (SDS), and two polymers, HPC and Soluplus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e6ba47fc839d66d5b6939bc83ff3247
https://doi.org/10.1016/j.powtec.2019.11.058

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Spray-Dried Amorphous Solid Dispersions of Griseofulvin in HPC/Soluplus/SDS: Elucidating the Multifaceted Impact of SDS as a Minor Component

Autor: Ecevit Bilgili, James Tarabokija, Nathaniel Parker, Mahbubur Rahman, Stephanie Ahmad

Publikováno v: Pharmaceutics
Volume 12
Issue 3
Pharmaceutics, Vol 12, Iss 3, p 197 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51d55cb04098011719834dc231f295b

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Synergistic and antagonistic effects of various amphiphilic polymer combinations in enhancing griseofulvin release from ternary amorphous solid dispersions

Autor: Keanu Radgman, Mahbubur Rahman, Alexander Coelho, Ecevit Bilgili, Stephanie Ahmad, James Tarabokija

Publikováno v: European Journal of Pharmaceutical Sciences. 150:105354

We aimed to elucidate the impact of various amphiphilic polymers on drug wettability and recrystallization inhibition and in turn drug release from binary and ternary amorphous solid dispersions (ASDs). Griseofulvin (GF) was selected as a challenging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527f076812c6fd174659b6368df0cf08
https://doi.org/10.1016/j.ejps.2020.105354

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