Zobrazeno 1 - 4
of 4
pro vyhledávání: '"James T.B. Crawley"'
Autor:
Adela Constantinescu-Bercu, Yuxiao A. Wang, Kevin J. Woollard, Pierre Mangin, Karen Vanhoorelbeke, James T.B. Crawley, Isabelle I. Salles-Crawley
Publikováno v:
Haematologica, Vol 107, Iss 4 (2021)
The GPIbT-VWF A1 domain interaction is essential for platelet tethering under high shear. Synergy between GPIbα and GPVI signaling machineries has been suggested previously, however its molecular mechanism remains unclear. We generated a novel GPIb
Externí odkaz:
https://doaj.org/article/419fac8344784940b97373c9c7ae8edd
Publikováno v:
EBioMedicine, Vol 2, Iss 8, Pp 942-952 (2015)
Background: Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease in which anti-ADAMTS13 autoantibodies cause severe enzyme deficiency. ADAMTS13 deficiency causes the loss of regulation of von Willebrand factor multimeric size a
Externí odkaz:
https://doaj.org/article/1288a79330974150bff683ec0d291f50
Background Severe deficiency in ADAMTS-13 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecfc93d5aa81d18bac28e2ea9a56e77
http://hdl.handle.net/10044/1/103127
http://hdl.handle.net/10044/1/103127
Autor:
Amna Malik, Anwar A. Sayed, Panpan Han, Michelle M.H. Tan, Eleanor Watt, Adela Constantinescu-Bercu, Alexander T.H. Cocker, Ahmad Khoder, Rocel Christine Saputil, Emma V. Thorley, Ariam Teklemichael, Yunchuan Ding, Alice C.J. Hart, Haiyu Zhang, Wayne A. Mitchell, Nesrina Imami, James T.B. Crawley, Isabelle I. Salles-Crawley, James B. Bussel, James L. Zehnder, Stuart Paul Adams, Bing M. Zhang, Nichola Cooper
Publikováno v:
Blood.
Immune thrombocytopenia (ITP) is traditionally considered an antibody-mediated disease. However, a number of features suggest alternative mechanisms of platelet destruction. In this study, we use a multi-dimensional approach to explore the role of cy