Zobrazeno 1 - 10
of 19
pro vyhledávání: '"James T. Shoemaker"'
Autor:
James T. Shoemaker, Wanrui Zhang, Selin I. Atlas, Richard A. Bryan, S. Walker Inman, Jelena Vukasinovic
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Remarkable advances in three-dimensional (3D) cell cultures and organ-on-a-chip technologies have opened the door to recapitulate complex aspects of human physiology, pathology, and drug responses in vitro. The challenges regarding oxygen delivery, t
Externí odkaz:
https://doaj.org/article/9056a615c4ca4da38ca6a102f3be0e15
Autor:
Peng Liu, Sophie Roberts, James T Shoemaker, Jelena Vukasinovic, Darren C Tomlinson, Valerie Speirs
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283044 (2023)
3D cell culture models of cancer are currently being developed to recapitulate in vivo physiological conditions and to assess therapeutic responses. However, most models failed to incorporate the biochemical and biophysical stimuli from fluid flow. I
Externí odkaz:
https://doaj.org/article/a1f3233e463f4959a479de1b5e0033e3
Publikováno v:
Journal of Microelectromechanical Systems. 29:653-660
We developed a new technology for the realization of composite biosensor systems, capable of measuring electrical and electrophysiological signals from electrogenic cells, using SeedEZTM 3D cell culture-scaffold material. This represents a paradigm-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d2552603e76ae08bd979adfe6e7d244
https://doi.org/10.1109/jmems.2020.3003452
https://doi.org/10.1109/jmems.2020.3003452
Autor:
Charles M, Didier, Avra, Kundu, James T, Shoemaker, Jelena, Vukasinovic, Swaminathan, Rajaraman
Publikováno v:
J Microelectromech Syst
We have developed a new technology for the realization of composite biosensor systems, capable of measuring electrical and electrophysiological signals from electrogenic cells, using SeedEZ™ 3D cell culture-scaffold material. This represents a para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fedb942cd22d831996cdbc7675a2e8d5
https://pubmed.ncbi.nlm.nih.gov/33762802
https://pubmed.ncbi.nlm.nih.gov/33762802
Autor:
Selin I Atlas, S Walker Inman, Jelena Vukasinovic, Wanrui Zhang, Richard A Bryan, James T. Shoemaker
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Remarkable advances in three-dimensional (3D) cell cultures and organ-on-a-chip technologies have opened the door to recapitulate complex aspects of human physiology, pathology, and drug responses in vitro. The challenges regarding oxygen delivery, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3625b6e932d625e04de7e158d6cd60af
https://doi.org/10.3389/fmolb.2020.568777
https://doi.org/10.3389/fmolb.2020.568777
Autor:
Jelena Vukasinovic, James T. Shoemaker, Adam I. Marcus, Jamie L. Arnst, Katherine R. Richardson
Publikováno v:
Cancer Research. 79:54-54
Modeling tissues in vitro has long consisted of two-dimensional (2D) monolayer cultures grown in a dish, flask, or multi-well plate. While these methods remain adequate for some applications, the advent of personalized cancer therapies has necessitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f12540d513dda5841b263f710cc13998
https://doi.org/10.1158/1538-7445.am2019-54
https://doi.org/10.1158/1538-7445.am2019-54
Autor:
Ravi V. Bellamkonda, Antoinette B. South, Kellie L. Templeman, Jeffrey C. Gaulding, L. Andrew Lyon, James T. Shoemaker, Michelle C. LaPlaca, Andrés J. García, Stacie M. Gutowski
Publikováno v:
Journal of Biomedical Materials Research Part A. 102:1486-1499
The performance of neural electrodes implanted in the brain is often limited by host response in the surrounding brain tissue, including astrocytic scar formation, neuronal cell death, and inflammation around the implant. We applied conformal microge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4fa88e73cd64834108c7fb39e935424
https://doi.org/10.1002/jbm.a.34799
https://doi.org/10.1002/jbm.a.34799
Autor:
Jelena Vukasinovic, James T. Shoemaker
Publikováno v:
Cancer Research. 77:4080-4080
A critical requirement for assessing drug toxicity in vitro is cytochrome P450 (CYP) function that is physiologically representative. Due to low levels of CYP enzyme activity, cell lines such as HepG2 hepatocytes have largely been supplanted with pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968eff7fb52e2b8e180e59c82c68e767
https://doi.org/10.1158/1538-7445.am2017-4080
https://doi.org/10.1158/1538-7445.am2017-4080
Autor:
Michelle C. LaPlaca, Robert A. Latour, James T. Shoemaker, Yang Wei, Ravi V. Bellamkonda, Kellie L. Templeman, Andrés J. García, Stacie M. Gutowski
Publikováno v:
Biomaterials. 44
Neural electrodes are an important part of brain-machine interface devices that can restore functionality to patients with sensory and movement disorders. Chronically implanted neural electrodes induce an unfavorable tissue response which includes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001a65b4904ade7e44f4e7add796be31
https://pubmed.ncbi.nlm.nih.gov/25617126
https://pubmed.ncbi.nlm.nih.gov/25617126
Autor:
Asha Shekaran, Taylor E. Kavanaugh, Michelle C. LaPlaca, Andrés J. García, James T. Shoemaker, Yuhong Fan, Robert E. Guldberg, Angela S.P. Lin
Publikováno v:
Bone. 68
Skeletal development and growth are complex processes regulated by multiple microenvironmental cues, including integrin–ECM interactions. The β1 sub-family of integrins is the largest integrin sub-family and constitutes the main integrin binding p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc843b2a9546749fe42772bb65f700f
https://pubmed.ncbi.nlm.nih.gov/25183373
https://pubmed.ncbi.nlm.nih.gov/25183373