Zobrazeno 1 - 10 of 15 pro vyhledávání: '"James T. Lim"'
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Akademický článek
Generating Ensembles of Gene Regulatory Networks to Assess Robustness of Disease Modules
Autor: James T. Lim, Chen Chen, Adam D. Grant, Megha Padi
Publikováno v: Frontiers in Genetics, Vol 11 (2021)
The use of biological networks such as protein–protein interaction and transcriptional regulatory networks is becoming an integral part of genomics research. However, these networks are not static, and during phenotypic transitions like disease ons
Externí odkaz: https://doaj.org/article/76ef5d723cda4c48859cbf5fd0d5079b
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Data from PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis
Autor: Sathish K.R. Padi, Andrew S. Kraft, Megha Padi, Richard B. Lock, David T. Teachey, Emanuel F. Petricoin, Valerie S. Calvert, Libia A. Leuvano, Neha Singh, James T. Lim
Despite significant progress in understanding the genetic landscape of T-cell acute lymphoblastic leukemia (T-ALL), the discovery of novel therapeutic targets has been difficult. Our results demonstrate that the levels of PIM1 protein kinase is eleva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fb17fe5c12d5989a1ac1e2b841d72d
https://doi.org/10.1158/1535-7163.c.6542848
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6
Abstract 4882: Multi-omics analysis of mechanisms underlying sensitivity of Merkel cell carcinoma to pyrvinium pamoate
Autor: Jiawen Yang, James T. Lim, Paul Victor, Rick G. Schnellmann, James A. DeCaprio, Megha Padi
Publikováno v: Cancer Research. 83:4882-4882
Background: Merkel Cell Carcinoma (MCC) is a highly aggressive neuroendocrine cutaneous malignancy arising from either Ultraviolet-induced mutagenesis or Merkel cell polyomavirus (MCPyV) integration. Pyrvinium Pamoate (PP), an FDA-approved anthelmint
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c261e3551c24728af7e41cf3b1258d09
https://doi.org/10.1158/1538-7445.am2023-4882
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7
Endoscopic Removal of a Fecalith or Fecomucolith in a Rectal Stump or Pouch
Autor: Asiri Arachchi, James T. Lim, Evie Yeap, Ratheesraj Ratinam, Zeev Duieb, Yeng Kwang Tay
Publikováno v: Annals of Coloproctology, Vol 37, Iss 5, Pp 346-348 (2021)
Annals of Coloproctology
Fecaliths or fecomucoliths can form in rectal stumps after a Hartmann procedure or in a coloneovaginal conduit. They can cause significant distress to the patient by causing symptoms such as discharge and odor. We describe a novel and effective metho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91faa31e7a1b61d8862ed145ab73668c
http://coloproctol.org/upload/pdf/ac-2021-00206-0029.pdf
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10
PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis
Autor: Neha Singh, James T. Lim, Richard B. Lock, David T. Teachey, Valerie S. Calvert, Sathish K.R. Padi, Emanuel F. Petricoin, Megha Padi, Libia A. Leuvano, Andrew S. Kraft
Publikováno v: Mol Cancer Ther
Despite significant progress in understanding the genetic landscape of T-cell acute lymphoblastic leukemia (T-ALL), the discovery of novel therapeutic targets has been difficult. Our results demonstrate that the levels of PIM1 protein kinase is eleva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5f9b27cf43bdbf2920f07ac4c8d02e
https://pubmed.ncbi.nlm.nih.gov/32753387
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