Zobrazeno 1 - 10
of 48
pro vyhledávání: '"James T Stevens"'
Autor:
John M. Clark, David M. Soderlund, Larry P. Sheets, Linda S. Mullin, Vincent J Piccirillo, Dana Sargent, Myra L. Weiner, James T Stevens
Publikováno v:
Toxicology. 171:3-59
The Food Quality Protection Act (FQPA) of 1996 requires the United States Environmental Protection Agency to consider the cumulative effects of exposure to pesticides having a 'common mechanism of toxicity.' This paper reviews the information availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78812a84613746b9ff9e2f52d1df92a3
https://doi.org/10.1016/s0300-483x(01)00569-8
https://doi.org/10.1016/s0300-483x(01)00569-8
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 56:69-109
An extensive safety database has been developed for the chlorotriazine herbicide, atrazine. The results from five oncogenicity studies conducted in the Sprague-Dawley rat, two studies in the Fischer 344 rat, and two studies in the CD-1 mouse were rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b17784fd98d5f69c43a92590b387e9e
https://doi.org/10.1080/009841099158169
https://doi.org/10.1080/009841099158169
Publikováno v:
Journal of Toxicology and Environmental Health, Part B. 1:59-79
The capacity of some synthetic chemicals, the so-called "endocrine-disrupting chemical," to alter hormonal activity, as well as the adequacy of the testing of chemicals to evaluate this capacity, has been called into question. Among the chemicals ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e822309c1620d40272ead6cf42f678
https://doi.org/10.1080/10937409809524543
https://doi.org/10.1080/10937409809524543
Publikováno v:
Journal of Toxicology and Environmental Health. 50:415-431
Recently, a major topic of discussion has been the impact of synthetic chemicals that possess the capacity to alter hormonal activity, the so-called “endocrine modulators,” with potentially the capacity to alter the reproductive capability of hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::504dc27aa5829d4899a4fc45868bcff4
https://doi.org/10.1080/00984109708983999
https://doi.org/10.1080/00984109708983999
Publikováno v:
Journal of Toxicology and Environmental Health Part A. 50:415-431
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66707272d131132ef4791908a98a8495
https://doi.org/10.1080/009841097160320
https://doi.org/10.1080/009841097160320
Autor:
Claude L. Hughes, James T. Stevens, George P. Daston, William R. Kelce, Rex A. Hess, Robert E. Chapin
Publikováno v:
Toxicological Sciences. 29:1-17
The ability of foreign compounds to affect the functioning of various endocrine systems is currently thought responsible for a wide variety of effects. The presentations in this Symposium reviewed the evidence for and against the involvement of endoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019b2b3bdbf47471d3000840bc6bea2a
https://doi.org/10.1093/toxsci/29.1.1
https://doi.org/10.1093/toxsci/29.1.1
Publikováno v:
Environmental Health Perspectives
Chlorotriazines are widely used in agriculture as broadleaf herbicides. The compounds specifically inhibit photosynthesis, and, as such, display little interaction with animal systems. However, a 24-month feeding study with atrazine (ATR) revealed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c3a52432da23771806ea858d88c2f6
https://doi.org/10.1289/ehp.94102s1129
https://doi.org/10.1289/ehp.94102s1129
Autor:
Charles B. Breckenridge, Lawrence T. Wetzel, M K Tennant, James T. Stevens, D S Hill, J C Eldridge
Publikováno v:
Journal of Toxicology and Environmental Health. 43:197-211
In an accompanying article (see pp. 183-196), it was reported that administration of very high doses of the chlorotriazine herbicides atrazine, simazine, and diaminochlorotriazine (DACT), a common metabolite, expressed antiestrogenic activity in uter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c2b32b60310cef1825495299b95343
https://doi.org/10.1080/15287399409531915
https://doi.org/10.1080/15287399409531915
Autor:
L G Luempert rd, D G Fleenor-Heyser, J C Eldridge, James T. Stevens, J H Gillis, Lawrence T. Wetzel, P C Extrom, Charles B. Breckenridge
Publikováno v:
Journal of Toxicology and Environmental Health. 43:155-167
Atrazine or simazine (s-chlorotriazines) was administered by gavage daily for 2 wk to female Sprague-Dawley and Fischer 344 rats at oral doses of 100 or 300 mg/kg to evaluate effects on body, ovary, uterus, and adrenal weights, estrous cycle stages,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd0e25a957de45a4f60f18a4bb5eb94
https://doi.org/10.1080/15287399409531912
https://doi.org/10.1080/15287399409531912
Autor:
James T. Stevens, Lawrence T. Wetzel, Jacqueline H. Gillis, Louis G. Luempert, Charles B. Breckenridge, J. Charles Eldridge
Publikováno v:
Journal of Toxicology and Environmental Health. 43:139-153
The symmetrical triazine herbicides have been used for the preemergence control of broadleaf weeds for nearly three decades. Recently, certain members of this class, primarily the chlorotriazines (substituted in the 2 position), have been shown to ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c2eeb5d51fa80718682831e3c8e542
https://doi.org/10.1080/15287399409531911
https://doi.org/10.1080/15287399409531911