Zobrazeno 1 - 10
of 114
pro vyhledávání: '"James T Nichols"'
Autor:
Amanda Stenzel, Abigail Mumme-Monheit, Juliana Sucharov, Macie Walker, Jennyfer M. Mitchell, Bruce Appel, James T. Nichols
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The Notch pathway is a cell-cell communication system which is critical for many developmental processes, including craniofacial development. Notch receptor activation induces expression of several well-known canonical targets including those encoded
Externí odkaz:
https://doaj.org/article/6cdb22d3163148f9b3231b1efa0ab234
Autor:
Raisa Bailon-Zambrano, Juliana Sucharov, Abigail Mumme-Monheit, Matthew Murry, Amanda Stenzel, Anthony T Pulvino, Jennyfer M Mitchell, Kathryn L Colborn, James T Nichols
Publikováno v:
eLife, Vol 11 (2022)
Human faces are variable; we look different from one another. Craniofacial disorders further increase facial variation. To understand craniofacial variation and how it can be buffered, we analyzed the zebrafish mef2ca mutant. When this transcription
Externí odkaz:
https://doaj.org/article/70d9e215b1144ca89bacd33d4b4e1708
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008507 (2019)
Deleterious genetic mutations allow developmental biologists to understand how genes control development. However, not all loss of function genetic mutants develop phenotypic changes. Many deleterious mutations only produce a phenotype in a subset of
Externí odkaz:
https://doaj.org/article/dbbd60bca2434366a651ab10d9081087
Autor:
Thomas Desvignes, Amy E. Robbins, Andrew Z. Carey, Raisa Bailon‐Zambrano, James T. Nichols, John H. Postlethwait, Kryn Stankunas
Publikováno v:
Developmental Dynamics. 251:1306-1321
Caudal fin symmetry characterizes teleosts and likely contributes to their evolutionary success. However, the coordinated development and patterning of skeletal elements establishing external symmetry remains incompletely understood. We explore the s
Autor:
John D. Schmidt, Matthew P. Ruffner, James T. Nichols, Isaac S. Rowe, Ryan D. Nolin, Kirsten F. Ford, William T. Smith, Alexandre Martin
Publikováno v:
AIAA SCITECH 2023 Forum.
Autor:
Juliana Sucharov, Raisa Bailon-Zambrano, Abigail Mumme-Monheit, Matthew Murry, Amanda Stenzel, Anthony T Pulvino, Jennyfer M Mitchell, Kathryn L Colborn, James T Nichols
Publikováno v:
eLife. 11
Human faces are variable; we look different from one another. Craniofacial disorders further increase facial variation. To understand craniofacial variation and how it can be buffered, we analyzed the zebrafish mef2ca mutant. When this transcription
Autor:
Juliana Sucharov, Raisa Bailon-Zambrano, Abigail Mumme-Monheit, Matthew Murry, Amanda Stenzel, Anthony T Pulvino, Jennyfer M Mitchell, Kathryn L Colborn, James T Nichols
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e39d698dcdbe60a25c5cd777a067d9f1
https://doi.org/10.7554/elife.79247.sa2
https://doi.org/10.7554/elife.79247.sa2
Autor:
Lindsey Barske, Amjad Askary, Elizabeth Zuniga, Bartosz Balczerski, Paul Bump, James T Nichols, J Gage Crump
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005967 (2016)
The intricate shaping of the facial skeleton is essential for function of the vertebrate jaw and middle ear. While much has been learned about the signaling pathways and transcription factors that control facial patterning, the downstream cellular me
Externí odkaz:
https://doaj.org/article/e88d9a61d0014da9a52c5bdfba89ad58
Autor:
Aniket V Gore, Brett Athans, James R Iben, Kristin Johnson, Valya Russanova, Daniel Castranova, Van N Pham, Matthew G Butler, Lisa Williams-Simons, James T Nichols, Erica Bresciani, Bejamin Feldman, Charles B Kimmel, Paul P Liu, Brant M Weinstein
Publikováno v:
eLife, Vol 5 (2016)
During embryonic development, cell type-specific transcription factors promote cell identities, while epigenetic modifications are thought to contribute to maintain these cell fates. Our understanding of how genetic and epigenetic modes of regulation
Externí odkaz:
https://doaj.org/article/d49e94f6588e42b886215463aa573ada
Autor:
Charles B. Kimmel, Bernardo Blanco-Sánchez, Whitney Oliva, Samuel D. Ahlquist, Charline Walker, Tom A. Titus, Alexander L. Wind, James T. Nichols, Peter Batzel, John H. Postlethwait, John Dowd
Publikováno v:
J Fish Biol
When considering relationships between genotype and phenotype we frequently ignore the fact that the genome of a typical animal, notably including that of a fish and a human, harbors a huge amount of foreign DNA. Some of it, including the DNA of “a