Zobrazeno 1 - 9
of 9
pro vyhledávání: '"James T, DeLigio"'
Autor:
Ruslan Novosiadly, Malcolm A. Smith, Peter J. Houghton, James T. DeLigio, David Surguladze, Marie C. Prewett, Heinz H. Fiebig, Nina Zanella, Gregory P. Donoho, Colleen A. Burns, Ying Wang, Christopher B. Damoci, Dale L. Ludwig, Michael Amatulli, Amelie Forest
Supplemental Tables 1-2 & Figures 1-4. Supplemental Table 1. Total IR, IR-A, IR-B, IGF-IR, IGF-I and IGF-II mRNA expression in preclinical models of pediatric solid tumors. Supplemental Table 2. Patient-derived xenograft models of lung adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a081c5e60efb4377fed1664d1b1a0c24
https://doi.org/10.1158/1541-7786.22511881.v1
https://doi.org/10.1158/1541-7786.22511881.v1
Autor:
Ruslan Novosiadly, Malcolm A. Smith, Peter J. Houghton, James T. DeLigio, David Surguladze, Marie C. Prewett, Heinz H. Fiebig, Nina Zanella, Gregory P. Donoho, Colleen A. Burns, Ying Wang, Christopher B. Damoci, Dale L. Ludwig, Michael Amatulli, Amelie Forest
Supplemental Information. This file contains Supplemental Materials and Methods, Tables and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c646aa5b0835e16453e5cd8af32839
https://doi.org/10.1158/1541-7786.22511884
https://doi.org/10.1158/1541-7786.22511884
Autor:
Margaret A. Park, Charles E. Chalfant, Shaun C. Stevens, H. Patrick MacKnight, Keli K. Doe, Gina S. Nazario-Muñoz, James T. DeLigio
Publikováno v:
Mol Cancer Res
Triple negative breast cancer (TNBC) has an unusually low 5-year survival rate linked to higher metastatic rates. Our laboratory recently delineated a role for the alternative RNA splicing (AS) of cytoplasmic polyadenylation element binding protein 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68589dc1c80d2ab2570c97893eb0c65b
https://doi.org/10.1158/1541-7786.mcr-18-1291
https://doi.org/10.1158/1541-7786.mcr-18-1291
Autor:
H Patrick, MacKnight, Daniel J, Stephenson, L Alexis, Hoeferlin, Savannah D, Benusa, James T, DeLigio, Kenneth D, Maus, Anika N, Ali, Jennifer S, Wayne, Margaret A, Park, Edward H, Hinchcliffe, Rhoderick E, Brown, John J, Ryan, Robert F, Diegelmann, Charles E, Chalfant
Publikováno v:
Sci Signal
The sphingolipid ceramide-1-phosphate (C1P) directly binds to and activates group IVA cytosolic phospholipase A(2) (cPLA(2)α) to stimulate the production of eicosanoids. Because eicosanoids are important in wound healing, we examined the repair of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::281384980fcb33eb98f47ff4a9d4a642
https://pubmed.ncbi.nlm.nih.gov/31796632
https://pubmed.ncbi.nlm.nih.gov/31796632
Publikováno v:
Journal of Biological Chemistry. 292:17909-17918
The translational regulator cytosolic polyadenylation element–binding protein 2 (CPEB2) has two isoforms, CPEB2A and CPEB2B, derived by alternative splicing of RNA into a mature form that either includes or excludes exon 4. Previously, we reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5714fae8c23326aee1e97cf7a41ec8da
https://doi.org/10.1074/jbc.m117.810127
https://doi.org/10.1074/jbc.m117.810127
Autor:
Amy L. Olex, Steven Murdock, Paula D. Bos, Mikhail G. Dozmorov, Nicholas M. Clark, Comfort C Effi, Leandro M. Martinez, James T. DeLigio
Publikováno v:
Cell Rep
Regulatory T (Treg) cell infiltration of solid tumors often correlates with poor prognosis, but their tumor-suppressive function lacks mechanistic understanding. Through a combination of transgenic mice, cell fate mapping, adoptive transfer, and co-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b13b76ad1ddfe322ebcc3cb34d58e0
https://doi.org/10.1016/j.celrep.2020.108482
https://doi.org/10.1016/j.celrep.2020.108482
Autor:
David Surguladze, Dale L. Ludwig, Ying Wang, Gregory P. Donoho, Nina Zanella, Ruslan D. Novosiadly, Christopher B. Damoci, Malcolm A. Smith, Colleen A. Burns, James T. DeLigio, Marie Prewett, Heinz H. Fiebig, Michael Amatulli, Peter J. Houghton, Amelie Forest
Publikováno v:
Molecular Cancer Research. 13:1615-1626
Despite a recent shift away from anti–insulin-like growth factor I receptor (IGF-IR) therapy, this target has been identified as a key player in the resistance mechanisms to various conventional and targeted agents, emphasizing its value as a thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b69b3f29f01f65c076e6f007937ac0
https://doi.org/10.1158/1541-7786.mcr-15-0279
https://doi.org/10.1158/1541-7786.mcr-15-0279
Publikováno v:
Cancer biologytherapy. 19(3)
Multidrug resistance (MDR) represents a major hindrance to the efficacy of cancer chemotherapeutics. While surgical resection, radiation, and chemotherapy can be used to reduce tumor size, the subsequent appearance of drug resistant cells is a freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f90b7744e06b7bcd9ffe539c1795c2a
https://pubmed.ncbi.nlm.nih.gov/29261027
https://pubmed.ncbi.nlm.nih.gov/29261027
Autor:
Douglas Burtrum, Maria B. Lebron, Christopher B. Damoci, James T. DeLigio, Kelly M. Credille, Helen Kotanides, Kaben D Schwartz, Marina Starodubtseva, Nick Loizos, Michael Amatulli, Laura Brennan, Marie Prewett, Yiwei Zhang, Paul Balderes, Inga J Duignan, Kris Persaud, David Surguladze, Keren Paz, Marguerita O’Mahony
Publikováno v:
Cancer biologytherapy. 15(9)
Stem cell factor receptor (c-Kit) exerts multiple biological effects on target cells upon binding its ligand stem cell factor (SCF). Aberrant activation of c-Kit results in dysregulated signaling and is implicated in the pathogenesis of numerous canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff273223f5c50fe7962bd95d5060367e
https://pubmed.ncbi.nlm.nih.gov/24921944
https://pubmed.ncbi.nlm.nih.gov/24921944