Zobrazeno 1 - 10
of 110 339
pro vyhledávání: '"James T"'
Autor:
Prasenjit Prasad Saha, Valentin Gogonea, Wendy Sweet, Maradumane L. Mohan, Khuraijam Dhanachandra Singh, James T. Anderson, Deepthi Mallela, Conner Witherow, Niladri Kar, Kate Stenson, Terri Harford, Michael A. Fischbach, J. Mark Brown, Sadashiva S. Karnik, Christine S. Moravec, Joseph A. DiDonato, Sathyamangla Venkata Naga Prasad, Stanley L. Hazen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Allosteric modulation is a central mechanism for metabolic regulation but has yet to be described for a gut microbiota-host interaction. Phenylacetylglutamine (PAGln), a gut microbiota-derived metabolite, has previously been clinically assoc
Externí odkaz:
https://doaj.org/article/135a6fb0bc4149b78a90558a91ecc051
Autor:
Sayan Ghosh, Ruchi Sharma, Sridhar Bammidi, Victoria Koontz, Mihir Nemani, Meysam Yazdankhah, Katarzyna M. Kedziora, Donna Beer Stolz, Callen T. Wallace, Cheng Yu-Wei, Jonathan Franks, Devika Bose, Peng Shang, Helena M. Ambrosino, James R. Dutton, Zhaohui Geng, Jair Montford, Jiwon Ryu, Dhivyaa Rajasundaram, Stacey Hose, José-Alain Sahel, Rosa Puertollano, Toren Finkel, J. Samuel Zigler, Yuri Sergeev, Simon C. Watkins, Eric S. Goetzman, Deborah A. Ferrington, Miguel Flores-Bellver, Kai Kaarniranta, Akrit Sodhi, Kapil Bharti, James T. Handa, Debasish Sinha
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Non-neovascular or dry age-related macular degeneration (AMD) is a multi-factorial disease with degeneration of the aging retinal-pigmented epithelium (RPE). Lysosomes play a crucial role in RPE health via phagocytosis and autophagy, which a
Externí odkaz:
https://doaj.org/article/9a768d2563fb4e4f839cd5a860fabad3
Autor:
Philip J. Turk, William E. Anderson, Ryan J. Burns, Shih-Hsiung Chou, Thomas E. Dobbs, James T. Kearns, Seth T. Lirette, Maggie SJ McCarter, Hieu M. Nguyen, Catherine L. Passaretti, Geoffrey A. Rose, Casey L. Stephens, Jing Zhao, Andrew D. McWilliams
Publikováno v:
Journal of Infection and Public Health, Vol 17, Iss 6, Pp 1125-1133 (2024)
Background: During the COVID-19 pandemic, analytics and predictive models built on regional data provided timely, accurate monitoring of epidemiological behavior, informing critical planning and decision-making for health system leaders. At Atrium He
Externí odkaz:
https://doaj.org/article/2c9cab3b814c40a190ac73875cb7cd6f
Autor:
Pawel Rajwa, Angelika Borkowetz, Thomas Abbott, Andrea Alberti, Anders Bjartell, James T. Brash, Riccardo Campi, Andrew Chilelli, Mitchell Conover, Niculae Constantinovici, Eleanor Davies, Bertrand De Meulder, Sherrine Eid, Mauro Gacci, Asieh Golozar, Haroon Hafeez, Samiul Haque, Ayman Hijazy, Tim Hulsen, Andreas Josefsson, Sara Khalid, Raivo Kolde, Daniel Kotik, Samu Kurki, Mark Lambrecht, Chi-Ho Leung, Julia Moreno, Rossella Nicoletti, Daan Nieboer, Marek Oja, Soundarya Palanisamy, Peter Prinsen, Christian Reich, Giulio Raffaele Resta, Maria J. Ribal, Juan Gómez Rivas, Emma Smith, Robert Snijder, Carl Steinbeisser, Frederik Vandenberghe, Philip Cornford, Susan Evans-Axelsson, James N'Dow, Peter-Paul M. Willemse
Publikováno v:
European Urology Open Science, Vol 63, Iss , Pp 81-88 (2024)
Combination therapies in metastatic hormone-sensitive prostate cancer (mHSPC), which include the addition of an androgen receptor signaling inhibitor and/or docetaxel to androgen deprivation therapy, have been a game changer in the management of this
Externí odkaz:
https://doaj.org/article/2d85793f9cc44ccc93db6faf76d2293f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Advanced instruments and methods need to be developed now to create a technical basis to support the negotiation of future nuclear arms control treaties. One new capability that is anticipated is the ability to confirm either the declared pr
Externí odkaz:
https://doaj.org/article/725d87e1d05c46d196986cb03a2da5b9
Autor:
Tracy Elsey-Quirk, Austin Lynn, Michael Derek Jacobs, Rodrigo Diaz, James T. Cronin, Lixia Wang, Haosheng Huang, Dubravko Justic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Vegetation dieback and recovery may be dependent on the interplay between infrequent acute disturbances and underlying chronic stresses. Coastal wetlands are vulnerable to the chronic stress of sea-level rise, which may affect their suscepti
Externí odkaz:
https://doaj.org/article/5d1e8fd42c044bd582f364b7b5a7a7e0
Autor:
Xavier Caseras, Emily Simmonds, Antonio F. Pardiñas, Richard Anney, Sophie E. Legge, James T. R. Walters, Neil A. Harrison, Michael C. O’Donovan, Valentina Escott-Price
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Recent research has highlighted the role of complement genes in shaping the microstructure of the brain during early development, and in contributing to common allele risk for Schizophrenia. We hypothesised that common risk variants for schi
Externí odkaz:
https://doaj.org/article/afc3d551ce024deab2980c9a2ca7ed60
Autor:
Kian Hong Kock, Patrick K. Kimes, Stephen S. Gisselbrecht, Sachi Inukai, Sabrina K. Phanor, James T. Anderson, Gayatri Ramakrishnan, Colin H. Lipper, Dongyuan Song, Jesse V. Kurland, Julia M. Rogers, Raehoon Jeong, Stephen C. Blacklow, Rafael A. Irizarry, Martha L. Bulyk
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Homeodomains (HDs) are the second largest class of DNA binding domains (DBDs) among eukaryotic sequence-specific transcription factors (TFs) and are the TF structural class with the largest number of disease-associated mutations in the Human
Externí odkaz:
https://doaj.org/article/fb03d33422b540199802faeaf082a440
Publikováno v:
Methods in Ecology and Evolution, Vol 15, Iss 4, Pp 744-755 (2024)
Abstract Ecological analyses typically involve many interacting variables. Ecologists often specify lagged interactions in community dynamics (i.e. vector‐autoregressive models) or simultaneous interactions (e.g. structural equation models), but th
Externí odkaz:
https://doaj.org/article/5f82d28fcbfa439db669087e11a03f4b
Autor:
J. Pedro Teixeira, David Perez Ingles, Jordan B. Barton, James T. Dean, Pablo Garcia, Susan J. Kunkel, Preeyaporn Sarangarm, Natalie K. Weiss, Christopher L. Schaich, Laurence W. Busse, Nathan D. Nielsen
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Data to support the use of specific vasopressors in septic shock are limited. Since angiotensin II (AT2) was approved by the Food and Drug Administration in 2017, multiple mechanistically distinct vasopressors are available to tre
Externí odkaz:
https://doaj.org/article/44cb25ba93fc446daac181d7c3c7cf82