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Autor:
Brenda Gerhardt, Brian Zambrowicz, Melanie K. Shadoan, Brian D. Hamman, Matthias Schneider, Jason Allen, Isaac Van Sligtenhorst, Adisak Suwanichkul, Deon D. Smith, Sabrina Jeter-Jones, Kenneth A. Platt, Jay Mitchell, Urvi Desai, Katerina V. Savelieva, Laura L. Kirkpatrick, Peter Vogel, David R. Powell, Jean-Pierre Revelli, James Syrewicz
Publikováno v:
Obesity. 19:1010-1018
The kinase suppressor of ras 2 (KSR2) gene resides at human chromosome 12q24, a region linked to obesity and type 2 diabetes (T2D). While knocking out and phenotypically screening mouse orthologs of thousands of druggable human genes, we found KSR2 k