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Parkinson's disease: Is it a consequence of human brain evolution?

Autor: Diederich, Nico J., James Surmeier, D., Uchihara, Toshiki, Grillner, Sten, Goetz, Christopher G.

Publikováno v: Movement Disorders; Apr2019, Vol. 34 Issue 4, p453-459, 7p

Creation of an open-access, mutation-defined fibroblast resource for neurological disease research

Autor: Wray, S, Self, M, Lewis, PA, Taanman, JW, Ryan, NS, Mahoney, CJ, Liang, Y, Devine, MJ, Sheerin, UM, Houlden, H, Morris, HR, Healy, D, Marti-Masso, JF, Preza, E, Barker, S, Sutherland, M, Corriveau, RA, D'Andrea, M, Schapira, AHV, Uitti, RJ, Guttman, M, Opala, G, Jasinska-Myga, B, Puschmann, A, Nilsson, C, Espay, AJ, Slawek, J, Gutmann, L, Boeve, BF, Boylan, K, Jon Stoessl, A, Ross, OA, Maragakis, NJ, Van Gerpen, J, Gerstenhaber, M, Gwinn, K, Dawson, TM, Isacson, O, Marder, KS, Clark, LN, Przedborski, SE, Finkbeiner, S, Rothstein, JD, Wszolek, ZK, Rossor, MN, Hardy, J, Gusella, JF, MacDonald, ME, Wheeler, VC, Ross, CA, Akimov, S, Arjomand, J, Thompson, LM, King, A, Hermanowicz, N, Winokur, S, Svendsen, CN, Mattis, V, Onorati, M, Cattaneo, E, Allen, ND, Kemp, PJ, Kim, KS, Przedborski, S, Feng, J, Lee, VMY, Trojanowski, JQ, James Surmeier, D, Henderson, CE, Maniatis, T, Eggan, K, Cudowicz, ME

Publikováno v: Wray, S; Self, M; Lewis, PA; Taanman, JW; Ryan, NS; Mahoney, CJ; et al.(2012). Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. PLoS ONE, 7(8). doi: 10.1371/journal.pone.0043099. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0hr9m7bt

Our understanding of the molecular mechanisms of many neurological disorders has been greatly enhanced by the discovery of mutations in genes linked to familial forms of these diseases. These have facilitated the generation of cell and animal models

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::858a8a3006d4e18ea535d6f3ffd2375b
http://www.escholarship.org/uc/item/0hr9m7bt

Chapter 28 - Overview: cell-based models of parkinson's disease

Autor: James Surmeier, D.

Publikováno v: In Parkinson's Disease 2008:369

Corticospinal-specific HCN expression in mouse motor cortex: Ih-dependent synaptic integration as a candidate microcircuit mechanism involved in motor control.

Autor: Sheets, Patrick L., Suter, Benjamin A., Kiritani, Taro, Savio Chan, C., James Surmeier, D., Shepherd, Gordon M. G.

Publikováno v: Journal of Neurophysiology; Nov2011, Vol. 106 Issue 5, p2216-2231, 16p