Zobrazeno 1 - 10
of 11
pro vyhledávání: '"James Suchy"'
Publikováno v:
Hong Kong Physiotherapy Journal, Vol 43, Iss 01, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/06dd4dc3f71d4102a9c56f8e4b2eadb8
Publikováno v:
Hong Kong Physiotherapy Journal. 43:1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be95c308692444936983e76e0368df9d
https://doi.org/10.1142/s101370252375001x
https://doi.org/10.1142/s101370252375001x
Autor:
Alexander Koshkaryev, Walid S. Kamoun, Gang Sun, Vasileios Askoxylakis, Lia Luus, Ross B. Fulton, James F. Sampson, Eric M. Tam, Andrew J. Sawyer, Zhaohua Richard Huang, Daryl C. Drummond, Anne-Sophie Dugast, Michael Santiago, James Suchy, Stephanie Grabow
Publikováno v:
Molecular Cancer Therapeutics. 19:270-281
Combinations of chemotherapy with immunotherapy have seen recent clinical success, including two approvals of anti–PD-1/L1 agents in combination with taxane-based chemotherapy in non–small cell lung cancer and triple-negative breast cancer. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d1de2be371c87bef464a4ffd8c4529
https://doi.org/10.1158/1535-7163.mct-19-0414
https://doi.org/10.1158/1535-7163.mct-19-0414
Autor:
Lia Luus, Vasileios Askoxylakis, John Wilton, Alexey Lugovskoy, Kenneth J. Olivier, Stephanie Grabow, Jaeyeon Kim, Christine Pien, Geoffrey Kuesters, Suresh K. Tipparaju, Melissa Geddie, Nancy Dumont, Mark E. Hayes, Alexander Koshkaryev, Sarah A Schihl, C. Patrick Reynolds, Rachel Blaydes, Andrew J. Sawyer, James D. Marks, Tad Kornaga, James Suchy, Charles O. Noble, Dmitri B. Kirpotin, Shinji Oyama, Neeraj Kohli, Zhaohua Richard Huang, Walid S. Kamoun, Daryl C. Drummond, Yu Zhou
Publikováno v:
Nature Biomedical Engineering. 3:264-280
Antibody-mediated tumour targeting and nanoparticle-mediated encapsulation can reduce the toxicity of antitumour drugs and improve their efficacy. Here, we describe the performance of a nanotherapeutic encapsulating a hydrolytically sensitive docetax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8e94f819de7e7f6ccdf49b01d0fee2
https://doi.org/10.1038/s41551-019-0385-4
https://doi.org/10.1038/s41551-019-0385-4
Antibody-mediated targeting of TNFR2 activates CD8 + T cells in mice and promotes antitumor immunity
Autor:
Wenlian Qiao, James Qiu, James Lulo, Jian Tang, Anne-Sophie Dugast, Ross B. Fulton, Galina Craig, Stephanie Grabow, Maja Razlog, James F. Sampson, Eric M. Tam, Sonia Feau, Alexander Koshkaryev, Neeraj Kohli, Kathy Zhang, Yang Jiao, Lia Luus, Adam Camblin, Jennifer Richards, Christina S. F. Wong, Daryl C. Drummond, James Suchy, Aniela Jakubowski, Michael Croft, Marco Muda, James D. Marks, Elizabeth Hutto, Vinodh B. Kurella, Yu Zhou, Andreas Raue, Hong Zhang, Lihui Xu, Fabien Dépis, Sandeep Kumar, Violette Paragas
Publikováno v:
Science Translational Medicine. 11
Tumor necrosis factor receptor 2 (TNFR2) is the alternate receptor for TNF and can mediate both pro- and anti-inflammatory activities of T cells. Although TNFR2 has been linked to enhanced suppressive activity of regulatory T cells (Tregs) in autoimm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5923342bbcf0a08d5a53784115771df
https://doi.org/10.1126/scitranslmed.aax0720
https://doi.org/10.1126/scitranslmed.aax0720
Autor:
Eric M, Tam, Ross B, Fulton, James F, Sampson, Marco, Muda, Adam, Camblin, Jennifer, Richards, Alexander, Koshkaryev, Jian, Tang, Vinodh, Kurella, Yang, Jiao, Lihui, Xu, Kathy, Zhang, Neeraj, Kohli, Lia, Luus, Elizabeth, Hutto, Sandeep, Kumar, James, Lulo, Violette, Paragas, Christina, Wong, James, Suchy, Stephanie, Grabow, Anne-Sophie, Dugast, Hong, Zhang, Fabien, Depis, Sonia, Feau, Aniela, Jakubowski, Wenlian, Qiao, Galina, Craig, Maja, Razlog, James, Qiu, Yu, Zhou, James D, Marks, Michael, Croft, Daryl C, Drummond, Andreas, Raue
Publikováno v:
Science translational medicine. 11(512)
Tumor necrosis factor receptor 2 (TNFR2) is the alternate receptor for TNF and can mediate both pro- and anti-inflammatory activities of T cells. Although TNFR2 has been linked to enhanced suppressive activity of regulatory T cells (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37f83727e9fb0372906f1265c50b70b8
https://pubmed.ncbi.nlm.nih.gov/31578241
https://pubmed.ncbi.nlm.nih.gov/31578241
Autor:
James Suchy, Doug McKeag
Publikováno v:
Medicine & Science in Sports & Exercise. 51:599-600
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6182d4147c11bacb6b11a73cc1fc11c9
https://doi.org/10.1249/01.mss.0000562293.56898.44
https://doi.org/10.1249/01.mss.0000562293.56898.44
Autor:
Christina Wong, Sara Ghassemifar, Daryl C. Drummond, Maja Razlog, Stephanie Grabow, Alexander Koshkaryev, Andrew J. Sawyer, James Suchy, Jennifer Richards, Eric M. Tam
Publikováno v:
Cancer Research. 79:2491-2491
Early attempts at using TNF superfamily members for anticancer therapies, TNF and FAS, led to serious systemic toxicities. However, the discovery of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) introduced an agonist capable of kill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b19641ec0503d80783d6a36a522831
https://doi.org/10.1158/1538-7445.am2019-2491
https://doi.org/10.1158/1538-7445.am2019-2491
Autor:
James F Sampson, Ross B Fulton, Vinodh B Kurella, Jennifer M Richards, Adam J Camblin, Christina S Wong, Alexander Koshkaryev, James E Lulo, James A Qiu, Sandeep Kumar, Lia Luus, Yang Jiao, James Suchy, Stephanie Grabow, Violette Paragas, Maja Razlog, Lihui Xi, Marco Muda, Daryl C Drummond, Eric M Tam, Andreas Raue
Publikováno v:
The Journal of Immunology. 202:195.11-195.11
TNFR2, an emerging therapeutic target in immuno-oncology, is upregulated upon T cell activation and is expressed by tumor-infiltrating effector and regulatory T (Treg) cells. We generated a novel monoclonal antibody, Y9, specific to murine TNFR2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::624e86a920e0d2baffd92d61cd0d3ecf
https://doi.org/10.4049/jimmunol.202.supp.195.11
https://doi.org/10.4049/jimmunol.202.supp.195.11
Publikováno v:
NeuroMolecular Medicine. 12:86-97
The full range of causative factors in Amyotrophic lateral sclerosis (ALS) remains elusive, but oxidative stress is recognized as a contributing factor. Mutations in Cu/Zn superoxide dismutase 1 (SOD-1), associated with familial ALS, promote widespre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704dc9c2873b71947aaaac165c2a53d4
https://doi.org/10.1007/s12017-009-8089-7
https://doi.org/10.1007/s12017-009-8089-7