Zobrazeno 1 - 5
of 5
pro vyhledávání: '"James Striebel"'
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-26 (2020)
Abstract Background Prion diseases and prion-like disorders, including Alzheimer’s disease and Parkinson’s disease, are characterized by gliosis and accumulation of misfolded aggregated host proteins. Ablating microglia in prion-infected brain by
Externí odkaz:
https://doaj.org/article/030e2056a940459dba0b82cc81e47223
Autor:
Brent Race, Kimberly D. Meade-White, Katie Phillips, James Striebel, Richard Race, Bruce Chesebro
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 5, Pp 833-837 (2014)
Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculate
Externí odkaz:
https://doaj.org/article/fde80a867a6d4fb1a8b2849940340944
Autor:
Brent Race, Kimberly D. Meade-White, Michael W. Miller, Kent D. Barbian, Richard Rubenstein, Giuseppe LaFauci, Larisa Cervenakova, Cynthia Favara, Donald Gardner, Dan Long, Michael Parnell, James Striebel, Suzette A. Priola, Anne Ward, Elizabeth S. Williams, Richard Race, Bruce Chesebro
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 9, Pp 1366-1376 (2009)
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy, or prion disease, that affects deer, elk, and moose. Human susceptibility to CWD remains unproven despite likely exposure to CWD-infected cervids. We used 2 nonhuman primate
Externí odkaz:
https://doaj.org/article/728aa7a33b464b64abcff9512600d648
Autor:
Bruce Chesebro, James Striebel, Alejandra Rangel, Katie Phillips, Andrew Hughson, Byron Caughey, Brent Race
Publikováno v:
mBio, Vol 6, Iss 5 (2015)
ABSTRACT Aggregation of misfolded host proteins in the central nervous system is believed to be important in the pathogenic process in several neurodegenerative diseases of humans, including prion diseases, Alzheimer's disease, and Parkinson's diseas
Externí odkaz:
https://doaj.org/article/da548ec526a5483a8b786727f710eeb9
Autor:
Bruce Chesebro, Brent Race, Kimberly Meade-White, Rachel Lacasse, Richard Race, Mikael Klingeborn, James Striebel, David Dorward, Gillian McGovern, Martin Jeffrey
Publikováno v:
PLoS Pathogens, Vol 6, Iss 3, p e1000800 (2010)
Prion diseases are fatal neurodegenerative diseases of humans and animals characterized by gray matter spongiosis and accumulation of aggregated, misfolded, protease-resistant prion protein (PrPres). PrPres can be deposited in brain in an amyloid-for
Externí odkaz:
https://doaj.org/article/34a789af87ec43b5a3dfb959fbdb1eee