Zobrazeno 1 - 10
of 19
pro vyhledávání: '"James Speyer"'
Autor:
Komal Jhaveri, Rui Wang, Eleonora Teplinsky, Sarat Chandarlapaty, David Solit, Karen Cadoo, James Speyer, Gabriella D’Andrea, Sylvia Adams, Sujata Patil, Sofia Haque, Tara O’Neill, Kent Friedman, Francisco J. Esteva, Clifford Hudis, Shanu Modi
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-8 (2017)
Abstract Background Targeted therapies in HER2-positive metastatic breast cancer significantly improve outcomes but efficacy is limited by therapeutic resistance. HER2 is an acutely sensitive Heat Shock Protein 90 (HSP90) client and HSP90 inhibition
Externí odkaz:
https://doaj.org/article/78b6e8d4c26b4748b7167315c71133ec
Autor:
Douglas K Marks, Nibash Budhathoki, John Kucharczyk, Faisal Fa’ak, Nina D’Abreo, Maryann Kwa, Magdalena Plasilova, Shubhada Dhage, Phyu Phyu Soe, Daniel Becker, Alexander Hindenburg, Johanna Lee, Megan Winner, Chinyere Okpara, Alison Daly, Darshi Shah, Angela Ramdhanny, Marleen Meyers, Ruth Oratz, James Speyer, Yelena Novik, Freya Schnabel, Simon A Jones, Sylvia Adams
Publikováno v:
The Oncologist. 27:89-96
PurposeProvide real-world data regarding the risk for SARS-CoV-2 infection and mortality in breast cancer (BC) patients on active cancer treatment.MethodsClinical data were abstracted from the 3778 BC patients seen at a multisite cancer center in New
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08bf51faace551a3655116e68acabddb
https://doi.org/10.1093/oncolo/oyab042
https://doi.org/10.1093/oncolo/oyab042
Autor:
Sandra Demaria, Derya Unutmaz, Nina Bhardwaj, Silvia C. Formenti, Judith D. Goldberg, Amy Tiersten, Yelena Novik, James Speyer, Deborah Axelrod, Nicholas Shuman, Tsivia Hochman, Leonard Liebes, Luis Chiriboga, Tze-Chiang Meng, Frank Martiniuk, Lina Kozhaya, Sylvia Adams
PDF file, 73K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e941155b1c7e8d3cc24e61f8b1abf4c
https://doi.org/10.1158/1078-0432.22451633.v1
https://doi.org/10.1158/1078-0432.22451633.v1
Autor:
Sandra Demaria, Derya Unutmaz, Nina Bhardwaj, Silvia C. Formenti, Judith D. Goldberg, Amy Tiersten, Yelena Novik, James Speyer, Deborah Axelrod, Nicholas Shuman, Tsivia Hochman, Leonard Liebes, Luis Chiriboga, Tze-Chiang Meng, Frank Martiniuk, Lina Kozhaya, Sylvia Adams
XLS file, 17K, Patient demographics, tumor characteristics, treatment, occurrence and severity of local and systemic adverse events and anti-tumor response per patient (n=10).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c37747be5fba5d7a74ff9460f7bf397
https://doi.org/10.1158/1078-0432.22451630
https://doi.org/10.1158/1078-0432.22451630
Autor:
Sandra Demaria, Derya Unutmaz, Nina Bhardwaj, Silvia C. Formenti, Judith D. Goldberg, Amy Tiersten, Yelena Novik, James Speyer, Deborah Axelrod, Nicholas Shuman, Tsivia Hochman, Leonard Liebes, Luis Chiriboga, Tze-Chiang Meng, Frank Martiniuk, Lina Kozhaya, Sylvia Adams
PDF file, 282K, A (non-responder 1): In situ TILs analysis by IHC in a patient with minimal T cell infiltrate before treatment (H&E stain and IHC for CD3, CD4, CD8 and FoxP3, 200x). B: (non-responder 2): In situ TILs analysis by IHC in a patient with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99efac0f0070a2a325128efab3e5feff
https://doi.org/10.1158/1078-0432.22451636.v1
https://doi.org/10.1158/1078-0432.22451636.v1
Autor:
Maryann Kwa, Kelly V Ruggles, Yelena Novik, Adrian A Franke, Angelina Volkova, Karina Flores, Martin J Blaser, James Speyer, Ruth Oratz, Marleen Meyers, Komal Jhaveri, Ezeddin Fadel, Shelby Zamora, Adriana Heguy, Jonas Schluter, Sylvia Adams
Purpose The functional composition and diversity of the gut microbiome (estrobolome) may affect breast cancer risk by modulation of systemic sex hormones. Gut bacteria with β-glucuronidase enzymatic activity may deconjugate estrogens, leading to inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2da20a3050e890a7bce78002eb851c5a
https://doi.org/10.21203/rs.3.rs-1447334/v1
https://doi.org/10.21203/rs.3.rs-1447334/v1
Autor:
John Mandeli, Franco M. Muggia, Robert C. Wallach, John J. Wright, James Speyer, Joan Sorich, Elizabeth R. Plimack, Howard S. Hochster, Scott Wadler, Carolyn D. Runowicz
Publikováno v:
Journal of Clinical Oncology. 22:120-126
Purpose To determine the antitumor activity of the novel topoisomerase I inhibitor 9-aminocamptothecin (9-AC) given over 72 hours every 2 weeks in patients with ovarian carcinoma previously treated with one platinum-containing regimen. Patients and M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ce14b74d77f347d6cf026e67ab0ede
https://doi.org/10.1200/jco.2004.03.016
https://doi.org/10.1200/jco.2004.03.016
Autor:
Frances McGill, Carmel Cohen, Alia Rozenblit, Carolyn D. Runowicz, Hilda Haynes, Jonathan J. Beitler, Scott Wadler, Gary L. Goldberg, James Speyer, John Rubin
Publikováno v:
Journal of Clinical Oncology. 11:1511-1516
PURPOSE A phase I trial of WR2721 was initiated to determine the maximal safe dose for incorporation into a consecutive 5-day schedule of cisplatin administered concurrently with radiation therapy in patients with cervical cancer. PATIENTS AND METHOD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cf2ee836a798089cea22b1287771e8
https://doi.org/10.1200/jco.1993.11.8.1511
https://doi.org/10.1200/jco.1993.11.8.1511
Autor:
Arnold Herskovic, James Speyer, H.G. Seydel, J. Tschan, Jay Cooper, L Leichman, Roger Byhardt, Richard Pazdur, Joseph Libnock
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 14:33-35
Forty-one evaluable patients with localized squamous cell carcinoma of the thoracic esophagus were treated by a course of radiation therapy (3000 cGy in 3 weeks), 5-Fluorouracil (5-FU) and Cis-platinum (Pt). This was followed by an esophagectomy in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2708517816d0a1a465be64e8a7cdd6e
https://doi.org/10.1016/0360-3016(88)90047-8
https://doi.org/10.1016/0360-3016(88)90047-8
Autor:
James Speyer
Publikováno v:
The ANNALS of the American Academy of Political and Social Science. 102:175-177
n/a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f27e88ce523c71d244a352a244bffa
https://doi.org/10.1177/000271622210200132
https://doi.org/10.1177/000271622210200132