Zobrazeno 1 - 10
of 14
pro vyhledávání: '"James Soh"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5422 (2021)
Survivors of sepsis often suffer from prolonged post-critical illness syndrome secondary to the immune system’s reprogramming. It is unclear if this process is static and pervasive due to methodological difficulties studying long-term outcomes of s
Externí odkaz:
https://doaj.org/article/c5b1aeb5f1b84c7ba7cec52f30c28649
Publikováno v:
Sunday, April 23.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f557d46afa4131c9754d45377a949d85
https://doi.org/10.1212/wnl.0000000000202872
https://doi.org/10.1212/wnl.0000000000202872
Publikováno v:
Nature medicine
The plasma level of apolipoprotein B (apoB) is among the strongest risk factors for coronary artery disease. Microsomal triglyceride transfer protein (MTP) plays a key role in the lipidation of nascent apoB and the secretion of apoB-containing lipopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9cf385bfeabe6927fa334a3aa990be
http://europepmc.org/articles/PMC4121125
http://europepmc.org/articles/PMC4121125
Publikováno v:
Journal of Immunoassay and Immunochemistry. 29:220-233
Phosphoglycerate kinase (PGK1) is a key enzyme in glycolysis that can also be released from certain cells. In the extracellular milieu, PGK1 reportedly acts as a disulphide reductase to activate plasmin, resulting in the production of angiostatin, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091d56ae201262efd3c954ecef00b685
https://doi.org/10.1080/15321810802119588
https://doi.org/10.1080/15321810802119588
Autor:
Enza Di Leo, Patrizia Tarugi, Mehmet Gündüz, M. Mahmood Hussain, Eda Özaydin, Meghan T. Walsh, James Soh, Jahangir Iqbal, Joby Josekutty
Background— The use of microsomal triglyceride transfer protein (MTP) inhibitors is limited to severe hyperlipidemias because of associated hepatosteatosis and gastrointestinal adverse effects. Comprehensive knowledge about the structure–function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f08347c13320f4865f95f26d48fa899
https://europepmc.org/articles/PMC4618089/
https://europepmc.org/articles/PMC4618089/
Autor:
Meghan Walsh, Jahangir Iqbal, Joby Josekutty, James Soh, Enza Di Leo, Eda Ozaydin, Mehmet Gunduz, Patrizia Tarugi, Mahmood Hussain
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Background: The use of microsomal triglyceride transfer protein (MTP) inhibitors is limited to severe hyperlipidemias due to associated hepatosteatosis. Comprehensive knowledge about the structure-function of MTP might help design new molecules that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83536dfcd483229e9d6fe617a478510f
https://doi.org/10.1161/atvb.35.suppl_1.547
https://doi.org/10.1161/atvb.35.suppl_1.547
Autor:
James Soh, M. Mahmood Hussain
Publikováno v:
Nutrition & Metabolism
Microsomal triglyceride transfer protein (MTTP) is an essential chaperone that assists in the assembly of apolipoprotein B-containing lipoproteins to transport lipids. We have shown that microRNA (miR)-30c regulates MTTP expression but other members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0bfceccd73e4835576382b3aa73ef9
https://pubmed.ncbi.nlm.nih.gov/24007526
https://pubmed.ncbi.nlm.nih.gov/24007526
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. Overproduction of lipoproteins, a process critically dependent on microsomal triglyceride transfer protein (MTP), can contribute to hyperlipidemia. We have shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3823394a0357d9a03bad5f66a592f7b5
https://doi.org/10.1161/atvb.33.suppl_1.a115
https://doi.org/10.1161/atvb.33.suppl_1.a115
Autor:
Fatima Anjum, Jason Lazar, Raj Wadgaonkar, Maher Albitar, M. Mahmood Hussain, James Soh, Satish Gowda
Publikováno v:
Pulmonary circulation. 3(4)
Pulmonary arterial hypertension (PAH) is a major complication of sickle cell disease (SCD). Low levels of apolipoprotein A1 (Apo-A1) have been implicated in the development of PAH in SCD. We speculate that lower levels of Apo-A1 are related to dysreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92097da2faf4566a181665fccecb02f
https://pubmed.ncbi.nlm.nih.gov/25006400
https://pubmed.ncbi.nlm.nih.gov/25006400
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. Overproduction of lipoproteins, a process critically dependent on microsomal triglyceride transfer protein (MTP), can contribute to hyperlipidemia. We show that micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bacc745ee857dc402b88a967f6729984
https://doi.org/10.1161/atvb.32.suppl_1.a326
https://doi.org/10.1161/atvb.32.suppl_1.a326