Zobrazeno 1 - 2
of 2
pro vyhledávání: '"James Shevchuk"'
Autor:
Michael J. Moore, Maggie Zhong, Johanna Hansen, Hans Gartner, Craig Grant, Mei Huang, Faith M. Harris, Naxin Tu, Natalie A. Bowerman, Kurt H. Edelmann, Thomas Barry, Olivier Herbin, Chin-Siean Tay, David J. DiLillo, Corinne E. Decker, Natasha Levenkova, James Shevchuk, Ankur Dhanik, Karoline A. Meagher, Amanda Karr, Jan Roos, Wen-yi Lee, David Suh, Mark Eckersdorff, T. Craig Meagher, Matthew Koss, Lakeisha Esau, Matthew A. Sleeman, Robert Babb, Gang Chen, Christos A. Kyratsous, William T. Poueymirou, John R. McWhirter, Vera A. Voronina, Chunguang Guo, Cagan Gurer, George D. Yancopoulos, Andrew J. Murphy, Lynn E. Macdonald
Publikováno v:
Science Immunology. 6
Despite the enormous promise of T cell therapies, the isolation and study of human T cell receptors (TCRs) of dedicated specificity remains a major challenge. To overcome this limitation, we generated mice with a genetically humanized system of T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b33325698a8f3396e20dc96afc9308
https://doi.org/10.1126/sciimmunol.abj4026
https://doi.org/10.1126/sciimmunol.abj4026
Autor:
Pamela Krueger, James Shevchuk, Joannie Bautista, Macdonald Lynn, Natasha Levenkova, Saurabh Wadhwa, Cagan Gurer, Johanna Hansen, Douglas MacDonald, Tammy T. Huang, Ashique Rafique, Kenneth S. Graham, Lakeisha Esau, Matthew C. Franklin, George Ehrlich, Ashok Badithe, George D. Yancopoulos, Maggie Zhong, Andrew J. Murphy, Chunguang Guo, Vera Voronina, Robert Babb, Gang Chen, Naxin Tu, Morton Lori C, Craig Grant, William Poueymirou, Karoline A Meagher, Wojtek Auerbach, John Mcwhirter
Publikováno v:
Proc Natl Acad Sci U S A
We describe a Kappa-on-Heavy (KoH) mouse that produces a class of highly diverse, fully human, antibody-like agents. This mouse was made by replacing the germline variable sequences of both the Ig heavy-chain (IgH) and Ig kappa (IgK) loci with the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce38a80d6c07387d0b8c0cfcb5399c34
https://pubmed.ncbi.nlm.nih.gov/31879340
https://pubmed.ncbi.nlm.nih.gov/31879340