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of 2
pro vyhledávání: '"James Seckler"'
Autor:
Santhosh Baby, Ryan Gruber, Joseph Discala, Veljko Puskovic, Nijo Jose, Feixiong Cheng, Michael Jenkins, James Seckler, Stephen Lewis
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Fentanyl is a high-potency opioid receptor agonist that elicits profound analgesia and suppression of breathing in humans and animals. To date, there is limited evidence as to whether changes in oxidant stress are important factors in any of the acti
Externí odkaz:
https://doaj.org/article/9a35cf88afbe47948afbfa675a87ad80
Autor:
Benjamin Gaston, Laura Smith, Jürgen Bosch, James Seckler, Diana Kunze, Janna Kiselar, Nadzeya Marozkina, Craig A. Hodges, Patrick Wintrobe, Kellen McGee, Tatiana S. Morozkina, Spencer T. Burton, Tristan Lewis, Timothy Strassmaier, Paulina Getsy, James N. Bates, Stephen J. Lewis
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
S-nitroso-l-cysteine (L-CSNO) behaves as a ligand. Its soluble guanylate cyclase–independent (sGC-independent) effects are stereoselective — that is, not recapitulated by S-nitroso-d-cysteine (D-CSNO) — and are inhibited by chemical congeners.
Externí odkaz:
https://doaj.org/article/0d6ea0f326f84f139e9fc944a5002b14