Zobrazeno 1 - 10 of 50 pro vyhledávání: '"James Schilling"'
1
Akademický článek
Targeted multiplex validation of CSF proteomic biomarkers: implications for differentiation of PCNSL from tumor-free controls and other brain tumors
Autor: Jingjing Ma, Zhiguang Lin, Yaqi Zhang, Yun Ding, Qiming Tang, Yufeng Qian, Bo Jin, Ruben Y. Luo, Wei-Li Liao, Sheeno Thyparambil, Zhi Han, C. James Chou, James Schilling, Qing Li, Mengxue Zhang, Yunan Lin, Yan Ma, Karl G. Sylvester, Seema Nagpal, Doff B. McElhinney, Xuefeng B. Ling, Bobin Chen
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionPrimary central nervous system lymphoma (PCNSL) is a rare type of non-Hodgkin’s lymphoma that affects brain parenchyma, eyes, cerebrospinal fluid, and spinal cord. Diagnosing PCNSL can be challenging because imaging studies often show s
Externí odkaz: https://doaj.org/article/dbd73c16b6144b0ab5b436e20370a0da
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2
Akademický článek
Exploring the feasibility of using long-term stored newborn dried blood spots to identify metabolic features for congenital heart disease screening
Autor: Scott R. Ceresnak, Yaqi Zhang, Xuefeng B. Ling, Kuo Jung Su, Qiming Tang, Bo Jin, James Schilling, C. James Chou, Zhi Han, Brendan J. Floyd, John C. Whitin, Kuo Yuan Hwa, Karl G Sylvester, Henry Chubb, Ruben Y. Luo, Lu Tian, Harvey J. Cohen, Doff B. McElhinney
Publikováno v: Biomarker Research, Vol 11, Iss 1, Pp 1-4 (2023)
Abstract Congenital heart disease (CHD) represents a significant contributor to both morbidity and mortality in neonates and children. There’s currently no analogous dried blood spot (DBS) screening for CHD immediately after birth. This study was s
Externí odkaz: https://doaj.org/article/4ced43196bca405f81c52ecdca242b45
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3
Akademický článek
Altered expression of the L-arginine/nitric oxide pathway in ovarian cancer: metabolic biomarkers and biological implications
Autor: Linfeng Chen, Qiming Tang, Keying Zhang, Qianyang Huang, Yun Ding, Bo Jin, Szumam Liu, KuoYuan Hwa, C. James Chou, Yani Zhang, Sheeno Thyparambil, Weili Liao, Zhi Han, Richard Mortensen, James Schilling, Zhen Li, Robert Heaton, Lu Tian, Harvey J. Cohen, Karl G. Sylvester, Rebecca C. Arent, Xinyang Zhao, Doff B. McElhinney, Yumei Wu, Wenpei Bai, Xuefeng B. Ling
Publikováno v: BMC Cancer, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Motivation Ovarian cancer (OC) is a highly lethal gynecological malignancy. Extensive research has shown that OC cells undergo significant metabolic alterations during tumorigenesis. In this study, we aim to leverage these metabolic changes
Externí odkaz: https://doaj.org/article/6a07bee1d1604685ad0ecd1e90a88f63
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4
Akademický článek
High-throughput quantitation of amino acids and acylcarnitine in cerebrospinal fluid: identification of PCNSL biomarkers and potential metabolic messengers
Autor: Jingjing Ma, Kun Chen, Yun Ding, Xiao Li, Qiming Tang, Bo Jin, Ruben Y. Luo, Sheeno Thyparambil, Zhi Han, C. James Chou, Ashlee Zhou, James Schilling, Zhiguang Lin, Yan Ma, Qing Li, Mengxue Zhang, Karl G. Sylvester, Seema Nagpal, Doff B. McElhinney, Xuefeng B. Ling, Bobin Chen
Publikováno v: Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Due to the poor prognosis and rising occurrence, there is a crucial need to improve the diagnosis of Primary Central Nervous System Lymphoma (PCNSL), which is a rare type of non-Hodgkin’s lymphoma. This study utilized targeted metabolom
Externí odkaz: https://doaj.org/article/7fd2a5974ad749da8d00e6f20aaa8cb5
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6
Akademický článek
Development of a Urine Metabolomics Biomarker-Based Prediction Model for Preeclampsia during Early Pregnancy
Autor: Yaqi Zhang, Karl G. Sylvester, Bo Jin, Ronald J. Wong, James Schilling, C. James Chou, Zhi Han, Ruben Y. Luo, Lu Tian, Subhashini Ladella, Lihong Mo, Ivana Marić, Yair J. Blumenfeld, Gary L. Darmstadt, Gary M. Shaw, David K. Stevenson, John C. Whitin, Harvey J. Cohen, Doff B. McElhinney, Xuefeng B. Ling
Publikováno v: Metabolites, Vol 13, Iss 6, p 715 (2023)
Preeclampsia (PE) is a condition that poses a significant risk of maternal mortality and multiple organ failure during pregnancy. Early prediction of PE can enable timely surveillance and interventions, such as low-dose aspirin administration. In thi
Externí odkaz: https://doaj.org/article/12f704f046f849cbb2610c1b43b80fd1
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7
Akademický článek
Serological Phenotyping Analysis Uncovers a Unique Metabolomic Pattern Associated With Early Onset of Type 2 Diabetes Mellitus
Autor: Linmin Zhu, Qianyang Huang, Xiao Li, Bo Jin, Yun Ding, C. James Chou, Kuo-Jung Su, Yani Zhang, Xingguo Chen, Kuo Yuan Hwa, Sheeno Thyparambil, Weili Liao, Zhi Han, Richard Mortensen, Yi Jin, Zhen Li, James Schilling, Karl G. Sylvester, Xuguo Sun, Xuefeng B. Ling
Publikováno v: Frontiers in Molecular Biosciences, Vol 9 (2022)
Background: Type 2 diabetes mellitus (T2DM) is a multifaceted disorder affecting epidemic proportion at global scope. Defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond effectively to insulin
Externí odkaz: https://doaj.org/article/31be4384527a49b5b3b7017cc4c556e1
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8
Akademický článek
Early-pregnancy prediction of risk for pre-eclampsia using maternal blood leptin/ceramide ratio: discovery and confirmation
Autor: Gary M Shaw, Xin Zhou, David K Stevenson, Sheeno Thyparambil, Shiying Hao, Xuefeng B Ling, Doff B McElhinney, John C Whitin, Harvey J Cohen, Karl G Sylvester, Jin You, Xiaoming Yao, Lihong Mo, Subhashini Ladella, Ronald J Wong, Zhen Li, Qianyang Huang, James Schilling, Wei-Li Liao, Shantay R Davies-Balch, Hangyi Zhao, David Fan
Publikováno v: BMJ Open, Vol 11, Iss 11 (2021)
Objective This study aimed to develop a blood test for the prediction of pre-eclampsia (PE) early in gestation. We hypothesised that the longitudinal measurements of circulating adipokines and sphingolipids in maternal serum over the course of pregna
Externí odkaz: https://doaj.org/article/81f96204b5804d3db0f402c0f9b67062
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9
Development of a Urine Metabolomics Biomarker-Based Prediction Model for Preeclampsia during Early Pregnancy
Autor: Ling, Yaqi Zhang, Karl G. Sylvester, Bo Jin, Ronald J. Wong, James Schilling, C. James Chou, Zhi Han, Ruben Y. Luo, Lu Tian, Subhashini Ladella, Lihong Mo, Ivana Marić, Yair J. Blumenfeld, Gary L. Darmstadt, Gary M. Shaw, David K. Stevenson, John C. Whitin, Harvey J. Cohen, Doff B. McElhinney, Xuefeng B.
Publikováno v: Metabolites; Volume 13; Issue 6; Pages: 715
Preeclampsia (PE) is a condition that poses a significant risk of maternal mortality and multiple organ failure during pregnancy. Early prediction of PE can enable timely surveillance and interventions, such as low-dose aspirin administration. In thi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::16248a355f7190b0db2ab9c330abaf52
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10
Early-pregnancy prediction of risk for pre-eclampsia using maternal blood leptin/ceramide ratio: discovery and confirmation
Autor: Doff B. McElhinney, Shantay R Davies-Balch, Gary M. Shaw, Qianyang Huang, Harvey J. Cohen, Ronald J. Wong, James Schilling, Subhashini Ladella, David Fan, Sheeno Thyparambil, Lihong Mo, Karl G. Sylvester, Xin Zhou, John C. Whitin, Shiying Hao, Jin You, Xuefeng B. Ling, Zhen Li, Xiaoming Yao, Hangyi Zhao, David K. Stevenson, Wei-Li Liao
Publikováno v: BMJ Open, Vol 11, Iss 11 (2021)
BMJ Open
ObjectiveThis study aimed to develop a blood test for the prediction of pre-eclampsia (PE) early in gestation. We hypothesised that the longitudinal measurements of circulating adipokines and sphingolipids in maternal serum over the course of pregnan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be00357946e11fb1c51789b0361c0155
https://bmjopen.bmj.com/content/11/11/e050963.full
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