Zobrazeno 1 - 10
of 10
pro vyhledávání: '"James Saliba"'
Autor:
Selina Gurri, Beat Siegenthaler, Michael Cangkrama, Gaetana Restivo, Marcel Huber, James Saliba, Reinhard Dummer, Volker Blank, Daniel Hohl, Sabine Werner
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-22 (2023)
Abstract Epithelial skin cancers are extremely common, but the mechanisms underlying their malignant progression are still poorly defined. Here, we identify the NRF3 transcription factor as a tumor suppressor in the skin. NRF3 protein expression is s
Externí odkaz:
https://doaj.org/article/70d51ab9fc7b4691a8599527533a94b1
Autor:
Sergio P Alpuche-Lazcano, James Saliba, Vivian V Costa, Gabriel H Campolina-Silva, Fernanda M Marim, Lucas S Ribeiro, Volker Blank, Andrew J Mouland, Mauro M Teixeira, Anne Gatignol
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 5, p e0009425 (2021)
Zika virus (ZIKV) infection of neurons leads to neurological complications and congenital malformations of the brain of neonates. To date, ZIKV mechanism of infection and pathogenesis is not entirely understood and different studies on gene regulatio
Externí odkaz:
https://doaj.org/article/435c988ad546417cb6504fb2c5fd46d2
Autor:
Marina Bury, Benjamin Le Calvé, Frédéric Lessard, Thomas Dal Maso, James Saliba, Carine Michiels, Gerardo Ferbeyre, Volker Blank
Publikováno v:
Cell Reports, Vol 29, Iss 6, Pp 1469-1481.e9 (2019)
Summary: Constitutive nuclear factor κB (NF-κB) activation is a hallmark of colon tumor growth. Cyclin-dependent kinases (CDKs) are critical cell-cycle regulators, and inhibition of CDK activity has been used successfully as anticancer therapy. Her
Externí odkaz:
https://doaj.org/article/489499579d474061815f59c4faf8ce61
Akademický článek
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Autor:
James Saliba, Baptiste Coutaud, Kiran Makhani, Noam Epstein Roth, Jennie Jackson, Joo Yeoun Park, Natascha Gagnon, Paolo Costa, Thiviya Jeyakumar, Marina Bury, Nicole Beauchemin, Koren K. Mann, Volker Blank
Publikováno v:
Oncogene. 41(11)
We investigated the role of the NFE2L3 transcription factor in inflammation-induced colorectal cancer. Our studies revealed that Nfe2l3−/− mice exhibit significantly less inflammation in the colon, reduced tumor size and numbers, and skewed local
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bf87a31fb903e6c2c75af6b36cedd4
https://pubmed.ncbi.nlm.nih.gov/35091681
https://pubmed.ncbi.nlm.nih.gov/35091681
Publikováno v:
BASE-Bielefeld Academic Search Engine
The file attached to this record is the author's final peer reviewed version. In the past few decades, there has been a significant increase in the rate of forced displacement, often precipitated by persecution, civil wars, terrorism, transborder con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dd34f69f1d6f4e249e6bdc5271828938
https://www.dora.dmu.ac.uk/handle/2086/18098
https://www.dora.dmu.ac.uk/handle/2086/18098
Autor:
Volker Blank, Gabriel Henrique Campolina-Silva, Mauro M. Teixeira, Vivian Vasconcelos Costa, Fernanda Martins Marim, James Saliba, Andrew J. Mouland, Anne Gatignol, Sergio P. Alpuche-Lazcano, Lucas S. Ribeiro
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 5, p e0009425 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 5, p e0009425 (2021)
Zika virus (ZIKV) infection of neurons leads to neurological complications and congenital malformations of the brain of neonates. To date, ZIKV mechanism of infection and pathogenesis is not entirely understood and different studies on gene regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118bff592cd126fc9ce02afd76e97cc0
https://doi.org/10.1371/journal.pntd.0009425
https://doi.org/10.1371/journal.pntd.0009425
Autor:
Volker Blank, Thomas Dal Maso, Gerardo Ferbeyre, James Saliba, Carine Michiels, Benjamin Le Calvé, Frédéric Lessard, Marina Bury
Publikováno v:
Cell Reports, Vol 29, Iss 6, Pp 1469-1481.e9 (2019)
Bury, M, Le Calve, B, Lessard, F, Dal Maso, T, Saliba, J, Michiels, C, Febeyre, G & Vloker, B 2019, ' NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor ', Cell Reports, vol. 29, no. 6, pp. 1469-1481.e9 . https://doi.org/10.1016/j.celrep.2019.09.087
Bury, M, Le Calve, B, Lessard, F, Dal Maso, T, Saliba, J, Michiels, C, Febeyre, G & Vloker, B 2019, ' NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor ', Cell Reports, vol. 29, no. 6, pp. 1469-1481.e9 . https://doi.org/10.1016/j.celrep.2019.09.087
Summary: Constitutive nuclear factor κB (NF-κB) activation is a hallmark of colon tumor growth. Cyclin-dependent kinases (CDKs) are critical cell-cycle regulators, and inhibition of CDK activity has been used successfully as anticancer therapy. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75489967a84dc3a6572ce4b3fe754ea9
https://doi.org/10.1016/j.celrep.2019.09.087
https://doi.org/10.1016/j.celrep.2019.09.087
Autor:
Frédéric Lessard, Marina Bury, James Saliba, T. Dal Maso, Carine Michiels, B. Le Calvé, Volker Blank
Publikováno v:
ESMO Open. 3:A66
Introduction Dysfunctional transcriptional and signalling networks play a fundamental role in colorectal cancer (CRC), one of the most common and fatal malignancies worldwide. Different molecular CRC subtypes have been identified, and understanding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b27f86c45b054ee67e63023dd15f25c
https://doi.org/10.1136/esmoopen-2018-eacr25.158
https://doi.org/10.1136/esmoopen-2018-eacr25.158
Autor:
James Saliba, Fabrice Dupuy, Anne Da Silva, Vincent Grassot, Jean-Michel Petit, Abderrahman Maftah
Publikováno v:
BMC Genomics
BMC Genomics, BioMed Central, 2014, 15 (1), pp.3-17. ⟨10.1186/1471-2164-15-621⟩
BMC Genomics 1 (15), 3-17. (2014)
BMC Genomics, BioMed Central, 2014, 15 (1), pp.3-17. ⟨10.1186/1471-2164-15-621⟩
BMC Genomics 1 (15), 3-17. (2014)
Background Myogenesis is initiated by myoblast differentiation and fusion to form myotubes and muscle fibres. A population of myoblasts, known as satellite cells, is responsible for post-natal growth of muscle and for its regeneration. This different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c354c94387526199111bcc88c9fad8
https://doi.org/10.1186/1471-2164-15-621
https://doi.org/10.1186/1471-2164-15-621