Zobrazeno 1 - 10
of 209
pro vyhledávání: '"James S. Ware"'
Autor:
Libor Pastika, Arunashis Sau, Konstantinos Patlatzoglou, Ewa Sieliwonczyk, Antônio H. Ribeiro, Kathryn A. McGurk, Sadia Khan, Danilo Mandic, William R. Scott, James S. Ware, Nicholas S. Peters, Antonio Luiz P. Ribeiro, Daniel B. Kramer, Jonathan W. Waks, Fu Siong Ng
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract The electrocardiogram (ECG) can capture obesity-related cardiac changes. Artificial intelligence-enhanced ECG (AI-ECG) can identify subclinical disease. We trained an AI-ECG model to predict body mass index (BMI) from the ECG alone. Develope
Externí odkaz:
https://doaj.org/article/9f47d99e612f4498bb4017febf439586
Autor:
Katherine S. Josephs, Angharad M. Roberts, Pantazis Theotokis, Roddy Walsh, Philip J. Ostrowski, Matthew Edwards, Andrew Fleming, Courtney Thaxton, Jason D. Roberts, Melanie Care, Wojciech Zareba, Arnon Adler, Amy C. Sturm, Rafik Tadros, Valeria Novelli, Emma Owens, Lucas Bronicki, Olga Jarinova, Bert Callewaert, Stacey Peters, Tom Lumbers, Elizabeth Jordan, Babken Asatryan, Neesha Krishnan, Ray E. Hershberger, C. Anwar A. Chahal, Andrew P. Landstrom, Cynthia James, Elizabeth M. McNally, Daniel P. Judge, Peter van Tintelen, Arthur Wilde, Michael Gollob, Jodie Ingles, James S. Ware
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background As the availability of genomic testing grows, variant interpretation will increasingly be performed by genomic generalists, rather than domain-specific experts. Demand is rising for laboratories to accurately classify variants in
Externí odkaz:
https://doaj.org/article/b19fec6981b54abc9f8f6edd48178160
Autor:
Mit Shah, Marco H. de A. Inácio, Chang Lu, Pierre-Raphaël Schiratti, Sean L. Zheng, Adam Clement, Antonio de Marvao, Wenjia Bai, Andrew P. King, James S. Ware, Martin R. Wilkins, Johanna Mielke, Eren Elci, Ivan Kryukov, Kathryn A. McGurk, Christian Bender, Daniel F. Freitag, Declan P. O’Regan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cardiovascular ageing is a process that begins early in life and leads to a progressive change in structure and decline in function due to accumulated damage across diverse cell types, tissues and organs contributing to multi-morbidity. Dama
Externí odkaz:
https://doaj.org/article/5ca4f1d3a73b4fbe9ffa76bdd765cf9c
Autor:
Catherine M. Francis, Matthias E. Futschik, Jian Huang, Wenjia Bai, Muralidharan Sargurupremraj, Alexander Teumer, Monique M. B. Breteler, Enrico Petretto, Amanda S. R. Ho, Philippe Amouyel, Stefan T. Engelter, Robin Bülow, Uwe Völker, Henry Völzke, Marcus Dörr, Mohammed-Aslam Imtiaz, N. Ahmad Aziz, Valerie Lohner, James S. Ware, Stephanie Debette, Paul Elliott, Abbas Dehghan, Paul M. Matthews
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Aortic distensibility is a risk factor for multiple cardiovascular events, but the genetic etiology is not well understood. Here, the authors identify genetic variants linked to aortic distensibility, highlighting mechanistic pathways and causal rela
Externí odkaz:
https://doaj.org/article/a5d0caf9381c40529e225078de909c70
Autor:
Arthur A. M. Wilde, Christopher Semsarian, Manlio F. Márquez, Alireza Sepehri Shamloo, Michael J. Ackerman, Euan A. Ashley, Back Sternick Eduardo, Héctor Barajas‐Martinez, Elijah R. Behr, Connie R. Bezzina, Jeroen Breckpot, Philippe Charron, Priya Chockalingam, Lia Crotti, Michael H. Gollob, Steven Lubitz, Naomasa Makita, Seiko Ohno, Martín Ortiz‐Genga, Luciana Sacilotto, Eric Schulze‐Bahr, Wataru Shimizu, Nona Sotoodehnia, Rafik Tadros, James S. Ware, David S. Winlaw, Elizabeth S. Kaufman, Takeshi Aiba, Andreas Bollmann, Jong‐Il Choi, Aarti Dalal, Francisco Darrieux, John Giudicessi, Mariana Guerchicoff, Kui Hong, Andrew D. Krahn, Ciorsti Mac Intyre, Judith A. Mackall, Lluís Mont, Carlo Napolitano, Pablo Ochoa Juan, Petr Peichl, Alexandre C. Pereira, Peter J. Schwartz, Jon Skinner, Christoph Stellbrink, Jacob Tfelt‐Hansen, Thomas Deneke
Publikováno v:
Journal of Arrhythmia, Vol 38, Iss 4, Pp 491-553 (2022)
Externí odkaz:
https://doaj.org/article/065b869d10df4d35a27b0f57e20fcc2b
Autor:
Ravi J. Amin, Deborah Morris-Rosendahl, Mat Edwards, Upasana Tayal, Rachel Buchan, Daniel J. Hammersley, Richard E. Jones, Sabiha Gati, Zohya Khalique, Batool Almogheer, Dudley J. Pennell, Arun John Baksi, Antonis Pantazis, James S. Ware, Sanjay K. Prasad, Brian P. Halliday
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundGuidelines recommend genetic testing and cardiovascular magnetic resonance (CMR) for the investigation of dilated cardiomyopathy (DCM). However, the incremental value is unclear. We assessed the impact of these investigations in determining
Externí odkaz:
https://doaj.org/article/83451483d5b64dff9239d02b24896315
Autor:
Kiran H. K. Patel, Xinyang Li, Jennifer K. Quint, James S. Ware, Nicholas S. Peters, Fu Siong Ng
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background Although obesity, defined by body mass index (BMI), has been associated with a higher risk of hospitalisation and more severe course of illness in Covid-19 positive patients amongst the British population, it is unclear if this tr
Externí odkaz:
https://doaj.org/article/594907203ef64465bb2d765383767d27
Publikováno v:
Wellcome Open Research, Vol 7 (2022)
Background: Taurine, 2-aminoethanesulfonic acid, is an amino acid found in animal products. Taurine is produced for human consumption as a supplement and ingredient in beverages. Supplementation is a safe, inexpensive, and effective treatment for dil
Externí odkaz:
https://doaj.org/article/29292c64a6b14158b6e3027d73c76e2a
Autor:
Kiran Haresh Kumar Patel, Xinyang Li, Xiao Xu, Lin Sun, Maddalena Ardissino, Prakash P. Punjabi, Sanjay Purkayastha, Nicholas S. Peters, James S. Ware, Fu Siong Ng
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundSmall-scale studies have linked obesity (Ob) and metabolic ill-health with proarrhythmic repolarisation abnormalities. Whether these are observed at a population scale, modulated by individuals’ genetics, and confer higher risks of ventri
Externí odkaz:
https://doaj.org/article/8596b433b8b4479bbd23d38357b5136c
Publikováno v:
Wellcome Open Research, Vol 7 (2022)
Background: Taurine, 2-aminoethanesulfonic acid, is an amino acid found in animal products. Taurine is produced for human consumption as a supplement and ingredient in beverages. Supplementation is a safe, inexpensive, and effective treatment for dil
Externí odkaz:
https://doaj.org/article/670afc085d824c2dab5e4a7f335b0f6c