Zobrazeno 1 - 10
of 29
pro vyhledávání: '"James S. Waldron"'
Publikováno v:
Stroke. 52
Background: Randomized trials comparing alteplase (ALT) to tenecteplase (TNK) in large vessel occlusion have reported higher rates of recanalization with evidence of better clinical outcomes. Our 10-hospital network (2 CSCs, 2PSCs, 6 non-SCs) switche
Autor:
Douglas J. Fox, Lisa Richards, S. M. Shams Kazmi, Katherine E. Olin, James S. Waldron, Andrew K. Dunn
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 37:3097-3109
Multiple studies have demonstrated that laser speckle contrast imaging (LSCI) has high potential to be a valuable cerebral blood flow monitoring technique during neurosurgery. However, the quantitative accuracy and sensitivity of LSCI is limited, and
Publikováno v:
Stroke. 50
Introduction: Cerebral vasospasm (CV) often follows aneurysmal subarachnoid hemorrhage (SAH) and, when severe, may lead to delayed cerebral ischemia (DCI) that can contribute substantially to morbidity and mortality. It is important to identify patie
Autor:
Douglas J. Fox, Andrew K. Dunn, Katherine E. Olin, S. M. Shams Kazmi, James S. Waldron, Lisa Richards
Publikováno v:
Dynamics and Fluctuations in Biomedical Photonics XIV.
Monitoring cerebral blood flow (CBF) during neurosurgery is essential for detecting ischemia in a timely manner for a wide range of procedures. Multiple clinical studies have demonstrated that laser speckle contrast imaging (LSCI) has high potential
Publikováno v:
Neurosurgery. 68:E835-E839
BACKGROUND AND IMPORTANCE: We report a patient with lumbar subdural hematoma secondary to intracranial subarachnoid hemorrhage (SAH) presenting with bilateral foot drop and describe our management. CLINICAL PRESENTATION: A 37-year-old woman presented
Autor:
Steven A. Mills, Andrew T. Parsa, Isaac Yang, James S. Waldron, Tarik Tihan, Russell O. Pieper, Michael E. Sughrue, Seunggu J. Han
Publikováno v:
Journal of Clinical Neuroscience. 17:1543-1547
The ability of glioma cells to escape the immune system remains a significant barrier to successful immunotherapy. Here we demonstrate that loss of the PTEN tumor suppressor gene, with associated activation of the PI3K/Akt/mTOR pathway, leads to a hu
Autor:
Brian J. Ahn, Shanna Fang, Courtney A. Crane, James S. Waldron, Seunggu J. Han, Andrew T. Parsa, Isaac Yang, Russell O. Pieper
Publikováno v:
NeuroReport. 20:1597-1602
B7 homolog 1 (B7-H1) is a recently discovered immunoresistance protein that is regulated posttranscriptionally after PTEN loss in malignant glioma, a deadly form of brain tumor. Here, the impact of gamma-interferon-mediated activation of B7-H1 was in
Autor:
Heather J. Fullerton, James S. Waldron, Steven W. Hetts, Christopher F. Dowd, Jennifer Armstrong-Wells, Michael T. Lawton, Nalin Gupta
Publikováno v:
Journal of Neurosurgery: Pediatrics. 4:439-444
Microcephalic osteodysplastic primordial dwarfism type II (MOPD II) is a rare genetic syndrome characterized by extremely small stature and microcephaly, and is associated in 25% of patients with intracranial aneurysms and moyamoya disease. Although
Publikováno v:
Journal of Neurosurgery. 110:572-582
Object To date, glioma immunotherapy has been focused mostly on stimulating antitumor peripheral lymphocyte responses; however, some data suggest that microglia and/or macrophages (not lymphocytes) are the predominant inflammatory cells infiltrating
Autor:
Michael T. Lawton, James S. Waldron
Publikováno v:
Operative Neurosurgery. 64:ons86-ons95
Objective Many symptomatic cavernous malformations deep in the anteroinferior basal ganglia are deemed to be inoperable and managed conservatively because transcortical, transsylvian-transinsular, and transcallosal approaches are unsuitable. We prese