Zobrazeno 1 - 10
of 183
pro vyhledávání: '"James S. Schwaber"'
Autor:
Sean J. O’Sullivan, Damani McIntosh-Clarke, James Park, Rajanikanth Vadigepalli, James S. Schwaber
Publikováno v:
Frontiers in Systems Neuroscience, Vol 15 (2021)
Alcohol withdrawal syndrome (AWS) is characterized by neuronal hyperexcitability, autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) likely plays a prominent role in the neurological processes underlying these
Externí odkaz:
https://doaj.org/article/ee4e039aba274d2a8f26a523ce0f09d5
Autor:
Alison Moss, Shaina Robbins, Sirisha Achanta, Lakshmi Kuttippurathu, Scott Turick, Sean Nieves, Peter Hanna, Elizabeth H. Smith, Donald B. Hoover, Jin Chen, Zixi (Jack) Cheng, Jeffrey L. Ardell, Kalyanam Shivkumar, James S. Schwaber, Rajanikanth Vadigepalli
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102713- (2021)
Summary: We developed a spatially-tracked single neuron transcriptomics map of an intrinsic cardiac ganglion, the right atrial ganglionic plexus (RAGP) that is a critical mediator of sinoatrial node (SAN) activity. This 3D representation of RAGP used
Externí odkaz:
https://doaj.org/article/ee23db1917214094b15a355b972b98d1
Autor:
Clara Leung, Shaina Robbins, Alison Moss, Maci Heal, Mahyar Osanlouy, Richard Christie, Navid Farahani, Corey Monteith, Jin Chen, Peter Hunter, Susan Tappan, Rajanikanth Vadigepalli, Zixi (Jack) Cheng, James S. Schwaber
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102795- (2021)
Summary: We developed and analyzed a single cell scale anatomical map of the rat intrinsic cardiac nervous system (ICNS) across four male and three female hearts. We find the ICNS has a reliable structural organizational plan across individuals that
Externí odkaz:
https://doaj.org/article/fe247268c56446aa98e12a51a962386b
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102433- (2021)
Externí odkaz:
https://doaj.org/article/24626201866d484fb4a1704c601972e4
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102143- (2021)
Summary: Vagal stimulation is emerging as the next frontier in bioelectronic medicine to modulate peripheral organ health and treat disease. The neuronal molecular phenotypes in the dorsal motor nucleus of the vagus (DMV) remain largely unexplored, l
Externí odkaz:
https://doaj.org/article/0cbfdd2f520e45ca88e2764880bebbec
Autor:
Sirisha Achanta, Jonathan Gorky, Clara Leung, Alison Moss, Shaina Robbins, Leonard Eisenman, Jin Chen, Susan Tappan, Maci Heal, Navid Farahani, Todd Huffman, Steve England, Zixi (Jack) Cheng, Rajanikanth Vadigepalli, James S. Schwaber
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101140- (2020)
Summary: We have developed and integrated several technologies including whole-organ imaging and software development to support an initial precise 3D neuroanatomical mapping and molecular phenotyping of the intracardiac nervous system (ICN). While q
Externí odkaz:
https://doaj.org/article/9761aa1e37f84ff7ba91080e960ac2e9
Autor:
Mary M. Staehle, Sean O’Sullivan, Rajanikanth Vadigepalli, Kate F. Kernan, Gregory E. Gonye, Babatunde A. Ogunnaike, James S. Schwaber
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Genes that establish the circadian clock have differential expression with respect to solar time in central and peripheral tissues. Here, we find circadian-time-induced differential expression in a large number of genes not associated with circadian
Externí odkaz:
https://doaj.org/article/551e27b17c1b42d0a192a40d48f5f35d
Autor:
James H. Park, Jonathan Gorky, Babatunde Ogunnaike, Rajanikanth Vadigepalli, James S. Schwaber
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Central coordination of cardiovascular function is accomplished, in part, by the baroreceptor reflex, a multi-input multi-output physiological control system that regulates the activity of the parasympathetic and sympathetic nervous systems via inter
Externí odkaz:
https://doaj.org/article/bfb9acd1ca3e4451bf90e3a22c97f2d5
Autor:
Sean J. O’Sullivan, Evangelia Malahias, James Park, Ankita Srivastava, Beverly A. S. Reyes, Jon Gorky, Rajanikanth Vadigepalli, Elisabeth J. Van Bockstaele, James S. Schwaber
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Drug-seeking in opioid dependence is due in part to the severe negative emotion associated with the withdrawal syndrome. It is well-established that negative emotional states emerge from activity in the amygdala. More recently, gut microflora have be
Externí odkaz:
https://doaj.org/article/e10e6c2bb0914d09a89494aeeef5eb70
Autor:
Michelle M. Gee, Eden Hornung, Suranjana Gupta, Adam J. H. Newton, Zixi (Jack) Cheng, William W. Lytton, Abraham M. Lenhoff, James S. Schwaber, Rajanikanth Vadigepalli
Publikováno v:
Experimental Physiology.