Zobrazeno 1 - 8
of 8
pro vyhledávání: '"James S. Liou"'
Publikováno v:
Journal of Biological Chemistry. 275:39001-39011
Ras is a well established modulator of apoptosis. Suppression of protein kinase C (PKC) activity can selectively induce apoptosis in cells expressing a constitutively activated Ras protein. We wished to determine whether reactive oxygen species serve
Publikováno v:
Cell Death & Differentiation. 5:984-995
The product of the ras proto-oncogene has been implicated as an essential signal transducer, involved in a variety of biological or pathological activities, including apoptosis. The aim of this investigation was to further explore the mechanisms of a
Autor:
James S Liou, Dean S. Morrell
Publikováno v:
Pediatric annals. 36(12)
Autor:
Cyrus Torchinsky, James S. Liou, Xiansi Zhao, Shannon L. Davis, Ling Shen, Brian Florence, Robert E. Ayer, Remco A. Spanjaard, Sarah J. Ames
Publikováno v:
Cancer research. 65(6)
p53 is a critical tumor suppressor which removes cells with DNA damage by regulating expression and activity of a select group of p53-induced genes (PIG) that subsequently induce apoptosis. PIG8 was also identified as a gene induced by etoposide and
Publikováno v:
Journal of cellular physiology. 198(2)
Suppression of PKC activity can selectively induce apoptosis in cells expressing a constitutively activated p21Ras protein. We demonstrate that continued expression of p21Ras activity is required in PKC-mediated apoptosis because farnesyltransferase
Publikováno v:
Endocrinology. 142(6)
Retinoic acid (RA) slows growth and induces differentiation of tumor cells through activation of RA receptors (RARs). However, melanoma cell lines display highly variable responsiveness to RA, which is a poorly understood phenomenon. By using Norther
Publikováno v:
The Journal of biological chemistry. 273(27)
The products of the ras genes are known to regulate cell proliferation and differentiation; recently, they have been found to play a role in apoptosis. The expression of oncogenic p21(ras) in a number of cell types, including Jurkat (a human T lympho
Publikováno v:
Journal of Cellular Physiology; Feb2004, Vol. 198 Issue 2, p277, 18p