Zobrazeno 1 - 10
of 126
pro vyhledávání: '"James S. Koopman"'
Publikováno v:
Epidemics, Vol 36, Iss , Pp 100484- (2021)
SARS-Cov-2 escape mutations (EM) have been detected and are spreading. Vaccines may need adjustment to respond to these or future mutations. We designed a population level model integrating both waning immunity and EM. We also designed a set of crite
Externí odkaz:
https://doaj.org/article/eaff9a304dec4f91b80a93003ea992e8
Autor:
James S. Koopman
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-4 (2017)
Abstract To achieve complete polio eradication, the live oral poliovirus vaccine (OPV) currently used must be phased out after the end of wild poliovirus transmission. However, poorly understood threats may arise when OPV use is stopped. To counter t
Externí odkaz:
https://doaj.org/article/a6a62c0d26b34b58a7b03e195595c6aa
Autor:
Andrew F. Brouwer, Marisa C. Eisenberg, Lester M. Shulman, Michael Famulare, James S. Koopman, Steve J. Kroiss, Musa Hindiyeh, Yossi Manor, Itamar Grotto, Joseph N. S. Eisenberg
Publikováno v:
J R Soc Interface
Environmental pathogen surveillance is a sensitive tool that can detect early-stage outbreaks, and it is being used to track poliovirus and other pathogens. However, interpretation of longitudinal environmental surveillance signals is difficult becau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51016c5f5ecc13dc43a92f7f68937766
https://europepmc.org/articles/PMC9114981/
https://europepmc.org/articles/PMC9114981/
Publikováno v:
Bull Math Biol
Polio can circulate unobserved in regions that are challenging to monitor. To assess the probability of silent circulation, simulation models can be used to understand transmission dynamics when detection is unreliable. Model assumptions, however, im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba2f7053715ecd2c998d72fc9664358
https://doi.org/10.1007/s11538-022-01014-6
https://doi.org/10.1007/s11538-022-01014-6
Autor:
Xing He, Mattia Prosperi, Jian-Guo Bian, Shannan N Rich, Iain Buchan, Yi Guo, Jae Min, Mo Wang, Matthew Sperrin, James S. Koopman
Publikováno v:
Nature Machine Intelligence
Big data, high-performance computing, and (deep) machine learning are increasingly becoming key to precision medicine—from identifying disease risks and taking preventive measures, to making diagnoses and personalizing treatment for individuals. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b47371195bd2ec188acb6294797b5ec
https://doi.org/10.1038/s42256-020-0197-y
https://doi.org/10.1038/s42256-020-0197-y
Publikováno v:
Journal of the Royal Society Interface
We developed an elaborated susceptible-infected-recovered (SIR) individual-based model (IBM) with pathogen strain drift, waning and cross immunity, implemented as a novel Java Runtime-Alterable-Model Platform (J-RAMP). This platform allows parameter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66dad54f1700f51d81e392b5ef2a66d5
http://europepmc.org/articles/PMC8611333
http://europepmc.org/articles/PMC8611333
Publikováno v:
Infectious Disease Modelling
As polio-endemic countries move towards elimination, infrequent first infections and incomplete surveillance make it difficult to determine when the virus has been eliminated from the population. Eichner and Dietz [American Journal of Epidemiology, 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6719e09ed853043ba27e8b6c60f06c2
https://doi.org/10.1016/j.idm.2019.06.003
https://doi.org/10.1016/j.idm.2019.06.003
Escape mutations (EM) to SARS-Cov-2 have been detected and are spreading. Vaccines may need adjustment to respond to these or future mutations. We designed a population level model integrating both waning immunity and EM. We also designed a set of cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0286be04b87d00f8fe02eac1f5c0e965
https://doi.org/10.1101/2021.01.19.21250114
https://doi.org/10.1101/2021.01.19.21250114
Autor:
James S. Koopman, Carl P. Simon
Reinfection with SARS-CoV-2 can result from either waning immunity, a drift in the virus that escapes previously stimulated immunity, or both. The nature of such reinfection risks will affect the choice of control tactics and vaccines. We constructed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30ec5378c62d57e6bd5e1d56ea0fe53e
https://doi.org/10.1101/2020.09.10.20192153
https://doi.org/10.1101/2020.09.10.20192153
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 10, p e1000969 (2010)
Influenza can be transmitted through respirable (small airborne particles), inspirable (intermediate size), direct-droplet-spray, and contact modes. How these modes are affected by features of the virus strain (infectivity, survivability, transferabi
Externí odkaz:
https://doaj.org/article/7cff8d28d6294dd6b875f39c1f232213