Zobrazeno 1 - 10
of 246
pro vyhledávání: '"James S, Blachly"'
Autor:
Nilesh Kapoor, Qiuhong Zhao, Andrew Stiff, Seema A. Bhat, Mirela I. Anghelina, Leslie A. Andritsos, James S. Blachly, Narendranath Epperla, Zeinab El Boghdadly, Michael R. Grever, Kerry A. Rogers
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 1005-1009 (2024)
Abstract Hairy cell leukemia is an uncommon B‐cell malignancy with excellent response to purine analogs and to targeted therapies such as ibrutinib and vemurafenib. However, purine analogs are known to be highly immunosuppressive and the infection
Externí odkaz:
https://doaj.org/article/d12158607d5649e69991ca098e4e599c
Autor:
Kaitlin Annunzio, Michael Ozga, Ying Huang, Mirela Anghelina, Seema A. Bhat, James S. Blachly, Michael R. Grever, Gerard Lozanski, Jasmine Neal, Polina Shindiapina, Kerry A. Rogers
Publikováno v:
eJHaem, Vol 4, Iss 4, Pp 1200-1202 (2023)
Externí odkaz:
https://doaj.org/article/f5a5e4450cd243178370f7aac4d9c690
Autor:
Zachary A. Hing, Janek S. Walker, Ethan C. Whipp, Lindsey Brinton, Matthew Cannon, Pu Zhang, Steven Sher, Casey B. Cempre, Fiona Brown, Porsha L. Smith, Claudio Agostinelli, Stefano A. Pileri, Jordan N. Skinner, Katie Williams, Hannah Phillips, Jami Shaffer, Larry P. Beaver, Alexander Pan, Kyle Shin, Charles T. Gregory, Gulcin H. Ozer, Selen A. Yilmaz, Bonnie K. Harrington, Amy M. Lehman, Lianbo Yu, Vincenzo Coppola, Pearlly Yan, Peggy Scherle, Min Wang, Philip Pitis, Chaoyi Xu, Kris Vaddi, Selina Chen-Kiang, Jennifer Woyach, James S. Blachly, Lapo Alinari, Yiping Yang, John C. Byrd, Robert A. Baiocchi, Bradley W. Blaser, Rosa Lapalombella
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Richter’s Transformation is a treatment-resistant and fatal progression from Chronic Lymphocytic Leukemia (CLL) to an aggressive lymphoma. Here, the authors show that PRMT5 is upregulated months prior to and after transformation, PRMT5 overexpressi
Externí odkaz:
https://doaj.org/article/69b4b26dffde485788921c4c7e1fc14a
Autor:
Farhad Ravandi, Robert J. Kreitman, Enrico Tiacci, Leslie Andritsos, Versha Banerji, Jacqueline C. Barrientos, Seema A. Bhat, James S. Blachly, Alessandro Broccoli, Timothy Call, Dai Chihara, Claire Dearden, Judit Demeter, Sasha Dietrich, Monica Else, Narendranath Epperla, Brunangelo Falini, Francesco Forconi, Douglas E. Gladstone, Alessandro Gozzetti, Sunil Iyengar, James B. Johnston, Jeffrey Jorgensen, Gunnar Juliusson, Francesco Lauria, Gerard Lozanski, Sameer A. Parikh, Jae H. Park, Aaron Polliack, Graeme Quest, Tadeusz Robak, Kerry A. Rogers, Alan Saven, John F. Seymour, Tamar Tadmor, Martin S. Tallman, Constantine S. Tam, Philip A. Thompson, Xavier Troussard, Clive S. Zent, Thorsten Zenz, Pier Luigi Zinzani, Bernhard Wörmann, Kanti Rai, Michael Grever
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 12, Pp 1-7 (2022)
Abstract A significant body of literature has been generated related to the detection of measurable residual disease (MRD) at the time of achieving complete remission (CR) in patients with hairy cell leukemia (HCL). However, due to the indolent natur
Externí odkaz:
https://doaj.org/article/b522c851a9074f98bd78424982d9e633
Autor:
Giovanni Marconi, Shukaib Arslan, Shaun Fleming, Antonio Curti, James S Blachly, Giovanni Martinelli, Matteo Giovanni Della Porta, Ashish Bajel, Tim Sauer, Martina Crysandt, Arnaud Pigneux, Marina Konopleva, Yotvat Marmor, Shringi Sharma, Nairouz Elgeioushi, Emily Rowe, Patricia Cheung, Ekaterina Jahn, Jamal Saeh, Raoul Tibes, Fathima Zumla Cader, Nitin Jain
Publikováno v:
HemaSphere, Vol 7, p e80196f1 (2023)
Externí odkaz:
https://doaj.org/article/5275a0432b0c4e3b8794b9932bafe30c
Autor:
Pinkal Desai, Sagar Lonial, Amanda Cashen, Manali Kamdar, James S. Blachly, Ian W. Flinn, Susan O’brien, Jacqueline Garcia, Neha Korde, Javid Moslehi, Margaret Wey, Patricia Cheung, Shringi Sharma, Damilola Olabode, Hong Chen, Firasath Ali Syed, Mary Liu, Jamal Saeh, Raoul Tibes, Marcio Andrade, Tapan Kadia
Publikováno v:
HemaSphere, Vol 7, p e98838e7 (2023)
Externí odkaz:
https://doaj.org/article/d5c07de1c1104e7abf60a32c2df2ca80
Autor:
Vera Binder, Wantong Li, Muhammad Faisal, Konur Oyman, Donn L. Calkins, Jami Shaffer, Emily M. Teets, Steven Sher, Andrew Magnotte, Alex Belardo, William Deruelle, T. Charles Gregory, Shelley Orwick, Elliott J. Hagedorn, Julie R. Perlin, Serine Avagyan, Asher Lichtig, Francesca Barrett, Michelle Ammerman, Song Yang, Yi Zhou, William E. Carson, Heather R. Shive, James S. Blachly, Rosa Lapalombella, Leonard I. Zon, Bradley W. Blaser
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112528- (2023)
Summary: Altered hematopoietic stem cell (HSC) fate underlies primary blood disorders but microenvironmental factors controlling this are poorly understood. Genetically barcoded genome editing of synthetic target arrays for lineage tracing (GESTALT)
Externí odkaz:
https://doaj.org/article/b0783af216d541e48c1e8e6815eda5bc
Publikováno v:
Haematologica, Vol 107, Iss 12 (2022)
Considerable progress has been made in the past several years in the scientific understanding of, and available treatments for, acute myeloid leukemia (AML). Achievement of a conventional remission, evaluated cytomorphologically via small bone marrow
Externí odkaz:
https://doaj.org/article/337eb01baade4d8d87dfc8f07b993f9d
Autor:
Janek S. Walker, Zachary A. Hing, Steven Sher, James Cronin, Katie Williams, Bonnie Harrington, Jordan N. Skinner, Casey B. Cempre, Charles T. Gregory, Alexander Pan, Max Yano, Larry P. Beaver, Brandi R. Walker, Jadwiga M. Labanowska, Nyla A. Heerema, Krzysztof Mrózek, Jennifer A. Woyach, Amy S. Ruppert, Amy Lehman, Hatice Gulcin Ozer, Vincenzo Coppola, Pearlly Yan, John C. Byrd, James S. Blachly, Rosa Lapalombella
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Some genes that are part of balanced translocations are reported as drivers for tumourigenesis. Here, the authors report a translocation involving MTCP1 in chronic lymphocytic leukemia and show that MTCP1 overexpression leads to the disease in a muri
Externí odkaz:
https://doaj.org/article/810bfd0089064a989b380ab83b7f18b0
Autor:
Alice S. Mims, Jessica Kohlschmidt, Uma Borate, James S. Blachly, Shelley Orwick, Ann-Kathrin Eisfeld, Dimitrios Papaioannou, Deedra Nicolet, Krzysztof Mrόzek, Eytan Stein, Bhavana Bhatnagar, Richard M. Stone, Jonathan E. Kolitz, Eunice S. Wang, Bayard L. Powell, Amy Burd, Ross L. Levine, Brian J. Druker, Clara D. Bloomfield, John C. Byrd
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-15 (2021)
Abstract Background Older patients (≥ 60 years) with acute myeloid leukemia (AML) often have multiple, sequentially acquired, somatic mutations that drive leukemogenesis and are associated with poor outcome. Beat AML is a Leukemia and Lymphoma Soci
Externí odkaz:
https://doaj.org/article/c4c6e83a72104dcd8a6a682632819213