Zobrazeno 1 - 5
of 5
pro vyhledávání: '"James Rottman"'
Autor:
Sandra L. Ross, Kaustav Biswas, James Rottman, Jennifer R. Allen, Jason Long, Les P. Miranda, Aaron Winters, Tara L. Arvedson
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
The iron exporter ferroportin and its ligand, the hormone hepcidin, control fluxes of stored and recycled iron for use in a variety of essential biochemical processes. Inflammatory disorders and malignancies are often associated with high hepcidin le
Externí odkaz:
https://doaj.org/article/b4f73a01607546a1b5d51be90e1d227f
Autor:
Melissa Bonner, Naoya Uchida, James Rottman, Julie Kanter, Matthew M. Hsieh, Manfred G. Schmidt, Alexis A. Thompson, Francis J. Pierciey, Mark C. Walters, Mohammed Asmal, John F. Tisdale, Laura Demopoulos
Publikováno v:
Blood Adv
Key Points Ability to accurately attribute adverse events post–gene therapy is required to describe the benefit-risk of these novel treatments. A SCD patient developed myelodysplastic syndrome post-LentiGlobin treatment; we show how insertional onc
Publikováno v:
Wave Motion. 105:102759
An approximate solution for the steady linear internal wave field generated by a localized, horizontally moving source in a thermocline is derived using ray and WKB (Wentzel–Kramers–Brillouin) theory. The waves are assumed to be steady in a refer
Autor:
Erika Rickel, Lori Siegel, James Rottman, Kelly Hensley, David Swart, Joel E Tocker, Alison Budelsky
Publikováno v:
The Journal of Immunology. 182:97.9-97.9
IL-25 is an IL-17 family ligand that promotes Th2 inflammatory responses. Intranasal (IN) administration of IL-25 into naïve mice induces pulmonary inflammation similar to allergic asthma. IL-25 has been reported to bind and signal through IL-17RB.
Autor:
Scott D. Lewis, Joseph M. Fraone, Ankit Makim, John L. Diener, David Fontana, H. Nicholas Marsh, H. A. Daniel Lagasse, Claude R. Benedict, James Rottman, Ryan M. Boomer, Renta Hutabarat, Jason R. Killough, Larry Cai, Madaline Gilbert, Patricia G. Merlino, Thomas Green Mccauley
Publikováno v:
Blood. 108:3930-3930
Following coronary artery damage, von Willebrand Factor (vWF) multimers adhere to exposed collagen via the vWF A3 domain. Platelets passing through damaged vessels under the conditions of high shear force associated with stenosed arteries will adhere