Zobrazeno 1 - 10
of 12
pro vyhledávání: '"James R. Zengel"'
Autor:
Wenjie Qiao, Christopher M. Richards, Youlim Kim, James R. Zengel, Siyuan Ding, Harry B. Greenberg, Jan E. Carette
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Human parechoviruses (PeV-A) are increasingly being recognized as a cause of infection in neonates and young infants, leading to a spectrum of clinical manifestations ranging from mild gastrointestinal and respiratory illnesses to severe sep
Externí odkaz:
https://doaj.org/article/565d9f6f35944e31ade567455e1f9786
Autor:
Christopher M. Richards, Sabrina Jabs, Wenjie Qiao, Lauren D. Varanese, Michaela Schweizer, Peter R. Mosen, Nicholas M. Riley, Malte Klüssendorf, James R. Zengel, Ryan A. Flynn, Arjun Rustagi, John C. Widen, Christine E. Peters, Yaw Shin Ooi, Xuping Xie, Pei-Yong Shi, Ralf Bartenschlager, Andreas S. Puschnik, Matthew Bogyo, Carolyn R. Bertozzi, Catherine A. Blish, Dominic Winter, Claude M. Nagamine, Thomas Braulke, Jan E. Carette
Publikováno v:
Science
Lysosomes are key degradative compartments of the cell. Transport to lysosomes relies on GlcNAc-1-phosphotransferase–mediated tagging of soluble enzymes with mannose 6-phosphate (M6P). GlcNAc-1-phosphotransferase deficiency leads to the severe lyso
Autor:
Scott B. Biering, Sylvia A. Sarnik, Eleanor Wang, James R. Zengel, Sarah R. Leist, Alexandra Schäfer, Varun Sathyan, Padraig Hawkins, Kenichi Okuda, Cyrus Tau, Aditya R. Jangid, Connor V. Duffy, Jin Wei, Rodney C. Gilmore, Mia Madel Alfajaro, Madison S. Strine, Xammy Nguyenla, Erik Van Dis, Carmelle Catamura, Livia H. Yamashiro, Julia A. Belk, Adam Begeman, Jessica C. Stark, D. Judy Shon, Douglas M. Fox, Shahrzad Ezzatpour, Emily Huang, Nico Olegario, Arjun Rustagi, Allison S. Volmer, Alessandra Livraghi-Butrico, Eddie Wehri, Richard R. Behringer, Dong-Joo Cheon, Julia Schaletzky, Hector C. Aguilar, Andreas S. Puschnik, Brian Button, Benjamin A. Pinsky, Catherine A. Blish, Ralph S. Baric, Wanda K. O’Neal, Carolyn R. Bertozzi, Craig B. Wilen, Richard C. Boucher, Jan E. Carette, Sarah A. Stanley, Eva Harris, Silvana Konermann, Patrick D. Hsu
Publikováno v:
Nature genetics, vol 54, iss 8
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a range of symptoms in infected individuals, from mild respiratory illness to acute respiratory distress syndrome. A systematic understanding of host factors influencing viral infect
Autor:
John J. Treanor, Yumiko Matsuoka, James R. Zengel, Hong Jin, Myeisha Paskel, Kanta Subbarao, Xing Cheng, Mariana Baz
Publikováno v:
Journal of Virology. 89:6907-6917
H3N8 influenza viruses are a commonly found subtype in wild birds, usually causing mild or no disease in infected birds. However, they have crossed the species barrier and have been associated with outbreaks in dogs, pigs, donkeys, and seals and ther
Autor:
James R. Zengel, Myeisha Paskel, Xing Cheng, Yumiko Matsuoka, Kanta Subbarao, Hong Jin, Mariana Baz, John J. Treanor
Publikováno v:
Journal of Virology. 89:1652-1659
Equine influenza viruses (EIV) are responsible for rapidly spreading outbreaks of respiratory disease in horses. Although natural infections of humans with EIV have not been reported, experimental inoculation of humans with these viruses can lead to
Autor:
Scott Jacobson, Rosemary Broome, Hong Jin, Stephanie Gee, Zhongying Chen, James R. Zengel, Janet Cetz, Amorsolo L. Suguitan, Paulyn Cha
Publikováno v:
Influenza and Other Respiratory Viruses
Objective The objective was to study passively acquired influenza H1N1 pandemic (H1N1pdm) maternal antibody kinetics and its impact on subsequent influenza infection and vaccination in ferrets during an outbreak of the H1N1pdm. Design and main outcom
Autor:
Xing Cheng, Mariana Baz, James R. Zengel, Hong Jin, Yumiko Matsuoka, Kanta Subbarao, Myeisha Paskel
Publikováno v:
Journal of Virology. 87:6901-6910
Since it is difficult to predict which influenza virus subtype will cause an influenza pandemic, it is important to prepare influenza virus vaccines against different subtypes and evaluate the safety and immunogenicity of candidate vaccines in precli
Autor:
James R. Zengel, Jackie Zhao, C. Kathy Wang, Hoyin Mok, Qi Xu, Bandita Parhy, Hong Jin, Xing Cheng
Publikováno v:
The Open Virology Journal
Live attenuated recombinant measles vaccine virus (MV) Edmonston-Zagreb (EZ) strain was evaluated as a viral vector to express the ectodomains of fusion protein of respiratory syncytial virus (RSV F) or glycoprotein 350 of Epstein-Barr virus (EBV gp3
Publikováno v:
Journal of Virology. 84:4936-4945
Influenza viruses attach to cells via a sialic acid moiety (sialic acid receptor) that is α2-3 linked or α2-6 linked to galactose (α2-3SAL or α2-6SAL); sialic acid acts as a receptor for the virus. Using lectin staining, we demonstrated that the
Publikováno v:
The Journal of infectious diseases. 208(4)
The humoral and cellular immune responses elicited by the trivalent live attenuated influenza vaccine (LAIV) and the trivalent inactivated influenza vaccine (TIV) were evaluated in the ferret model, using newly developed ferret immunological reagents