Zobrazeno 1 - 10
of 23
pro vyhledávání: '"James R. Woodworth"'
Autor:
Howard Trachtman, James R Woodworth, Frank S. Czerwiec, Krishna Padmanabhan, Leslie Johnson, Hiddo J.L. Heerspink, Youssef M K Farag, Debbie S. Gipson, Caitlin Cornwall, Xin-Ru Pan-Zhou, Liron Walsh, John F. Reilly, Katherine R. Tuttle, Gregory A Gaich
Publikováno v:
Kidney International Reports
Kidney International Reports, 6(10), 2575-2584. ELSEVIER SCIENCE INC
Kidney International Reports, 6(10), 2575-2584. ELSEVIER SCIENCE INC
Introduction A critical unmet need exists for precision therapies for chronic kidney disease. GFB-887 is a podocyte-targeting, small molecule inhibitor of transient receptor potential canonical-5 (TRPC5) designed specifically to treat patients with g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6c0b3abeba4b2e847543ef791e55a7
https://hdl.handle.net/11370/17a83b12-f9dd-4425-8420-3edef2a6da99
https://hdl.handle.net/11370/17a83b12-f9dd-4425-8420-3edef2a6da99
Autor:
James R. Woodworth, Michael L. Zeckel
This chapter seeks to provide an overview of clinically useful information regarding the pharmacokinetics, clinical uses, and safety profile of vancomycin. Vancomycin exhibits poor oral bioavailability. Following oral administration, only trace amoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca6168a610d58c03cc3b2b7d2217507
https://doi.org/10.1201/9781003067269-9
https://doi.org/10.1201/9781003067269-9
Publikováno v:
Diabetes Technology & Therapeutics. 6:147-153
A model was established allowing prediction of blood glucose response from glucose clamp results performed in healthy volunteers. Data from published studies performed in healthy volunteers were used to establish, test, and validate a model for the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a092ef13cddbe7575f746b91abe0d1
https://doi.org/10.1089/152091504773731339
https://doi.org/10.1089/152091504773731339
Autor:
Ronald R. Bowsher, Ronald E. Chance, William E. Legan, James R. Woodworth, Renee A. Lynch, Patricia Brown-Augsburger, Paula F. Santa
Publikováno v:
Clinical Chemistry. 45:104-110
Insulin lispro is an insulin analog in which the primary sequence has been altered by the inversion of amino acids B28 and B29. To date, it has not been possible to specifically measure insulin lispro in the presence of endogenous insulin because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aab26e78f7f86be8e5fe12baba09f735
https://doi.org/10.1093/clinchem/45.1.104
https://doi.org/10.1093/clinchem/45.1.104
Autor:
Stephanie A. Amiel, Stonny E. Joseph, David Hopkins, Mark L. Evans, James R. Woodworth, Jonathan M Janes, Anna Korzon-Burakowska
Publikováno v:
Diabetes Care. 21:2098-2102
OBJECTIVE To assess the effect of mixing the insulin analog lispro (Humalog) with NPH (Humulin I) before injection on lispro's fast, short action profile. RESEARCH DESIGN AND METHODS A total of 12 healthy volunteers received subcutaneous abdominal in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f592eb2df24a1cf8c9c5e9865a0c52c7
https://doi.org/10.2337/diacare.21.12.2098
https://doi.org/10.2337/diacare.21.12.2098
Autor:
Joyce Downing-Shelton, Ronald R. Bowsher, Rocco L. Brunelle, Paula F. Santa, Daniel C. Howey, Howard Rowe, James R. Woodworth
Publikováno v:
Clinical Pharmacology & Therapeutics. 58:459-469
Background [Lys(B28), Pro(B29)]-human insulin (lispro) is an insulin analogue with a reduced capacity for self-association and faster absorption from subcutaneous injection sites. We hypothesized that administration of lispro closer to a meal would r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b724deb8e2b7074aaa58d417edd39c
https://doi.org/10.1016/0009-9236(95)90060-8
https://doi.org/10.1016/0009-9236(95)90060-8
Autor:
Howard Rowe, Benito J. Cerimele, Rocco L. Brunelle, Joyce A. Compton, James R. Woodworth, Daniel C. Howey, Ronald R. Bowsher
Publikováno v:
Diabetes Care. 17:366-371
OBJECTIVE To compare and contrast the pharmacokinetics and glucodynamics of two insulin mixtures, one of 50% NPH human insulin and 50% Regular human insulin (50/50) and one of 70% NPH human insulin and 30% Regular human insulin (70/30), in healthy ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be830329db603c00525503ff315a4f9
https://doi.org/10.2337/diacare.17.5.366
https://doi.org/10.2337/diacare.17.5.366
Publikováno v:
Diabetes. 43:396-402
[Lys(B28, Pro(B29)]-human insulin (LYSPRO) is an insulin analogue in which the natural amino acid sequence of the B-chain at positions 28 and 29 is inverted. These changes result in an insulin molecule with a greatly reduced capacity for self-associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f88174fb1bfcedf239e2f67a81f4a38
https://doi.org/10.2337/diab.43.3.396
https://doi.org/10.2337/diab.43.3.396
Publikováno v:
Diabetes Care. 17:64-69
OBJECTIVE To provide distinct definitions and quantify the establishment of onset, peak, and duration of action for insulins. RESEARCH DESIGN AND METHODS We administered single subcutaneous doses of 10 U regular insulin to 10 volunteer subjects and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b3a1265d390b3b261d64c87f6b20ad
https://doi.org/10.2337/diacare.17.1.64
https://doi.org/10.2337/diacare.17.1.64
Publikováno v:
Journal of Antimicrobial Chemotherapy. 33:655-659
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e14050f60fa1124c70e03a4a5a65d0
https://doi.org/10.1093/jac/33.3.655
https://doi.org/10.1093/jac/33.3.655