Zobrazeno 1 - 10
of 56
pro vyhledávání: '"James R. Whiteford"'
Publikováno v:
Open Biology, Vol 11, Iss 2 (2021)
The syndecans are the major family of transmembrane proteoglycans, usually bearing multiple heparan sulfate chains. They are present on virtually all nucleated cells of vertebrates and are also present in invertebrates, indicative of a long evolution
Externí odkaz:
https://doaj.org/article/a4cb9eb517d54f07a3e350cde6804c19
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Syndecans are a four member multifunctional family of cell surface molecules with diverse biological roles. Syndecan-3 (SDC3) is the largest of these, but in comparison to the other family members relatively little is known about this molecule. SDC3
Externí odkaz:
https://doaj.org/article/086f1795ca604df4bf477356af5015b0
Autor:
Kate E. Hawkins, Shona Joy, Juliette M.K.M. Delhove, Vassilios N. Kotiadis, Emilio Fernandez, Lorna M. Fitzpatrick, James R. Whiteford, Peter J. King, Juan P. Bolanos, Michael R. Duchen, Simon N. Waddington, Tristan R. McKay
Publikováno v:
Cell Reports, Vol 14, Iss 8, Pp 1883-1891 (2016)
The potential of induced pluripotent stem cells (iPSCs) in disease modeling and regenerative medicine is vast, but current methodologies remain inefficient. Understanding the cellular mechanisms underlying iPSC reprogramming, such as the metabolic sh
Externí odkaz:
https://doaj.org/article/272ceabc933b4f23acf31d95556d9320
Autor:
Giulia De Rossi, James R. Whiteford
Publikováno v:
F1000Research, Vol 2 (2013)
Syndecan-3 is one of the four members of the syndecan family of heparan sulphate proteoglycans and has been shown to interact with numerous growth factors via its heparan sulphate chains. The extracellular core proteins of syndecan-1,-2 and -4 all po
Externí odkaz:
https://doaj.org/article/7bd6bb51272b4f148f43cf983a2940e5
Autor:
Frances Balkwill, James R. Whiteford, Richard Thompson, Robert E. Hollingsworth, Haihong Zhong, David A. Leinster, Kairbaan Hodivala-Dilke, Louise E. Reynolds, Oliver M.T. Pearce, Carla Milagre, Ganga Gopinathan
Supplementary Figures S1-S7. Western blot quantification of pERK and pSTAT3 from aortic lysates (S1); Western blot quantification of pERK and pSTAT3 from MLEC lysates (S2); Western blot analysis and quantification of pERK and pSTAT3 from HUVEC lysate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f1652258a02215fcd0f142e8883b3e
https://doi.org/10.1158/0008-5472.22405032.v1
https://doi.org/10.1158/0008-5472.22405032.v1
Autor:
Frances Balkwill, James R. Whiteford, Richard Thompson, Robert E. Hollingsworth, Haihong Zhong, David A. Leinster, Kairbaan Hodivala-Dilke, Louise E. Reynolds, Oliver M.T. Pearce, Carla Milagre, Ganga Gopinathan
Legend for Supplementary Figures S1-S7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47659289113ba6140c957d0a6e7c3496
https://doi.org/10.1158/0008-5472.22405035.v1
https://doi.org/10.1158/0008-5472.22405035.v1
Autor:
Amelia Filippelli, Mauro Perretti, Raffaella Belvedere, Antonello Petrella, Nunzia Novizio, Emanuela Pessolano, James R. Whiteford
Publikováno v:
The FEBS Journal. 288:6428-6446
Mesoglycan is a mixture of glycosaminoglycans (GAG) with fibrinolytic effects and the potential to enhance skin wound repair. Here, we have used endothelial cells isolated from wild-type (WT) and Syndecan-4 null (Sdc4-/-) C57BL/6 mice to demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efbedd5c660191005845237bb23096e
https://doi.org/10.1111/febs.16043
https://doi.org/10.1111/febs.16043
Publikováno v:
The international journal of biochemistrycell biology. 146
The heparan sulphate proteoglycan Syndecan-4 belongs to a 4-member family of transmembrane receptors. Genetic deletion of Syndecan-4 in mice causes negligible developmental abnormalities however when challenged these animals show distinct phenotypes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222daddf65caeb2a52501164113ab51f
https://pubmed.ncbi.nlm.nih.gov/35331918
https://pubmed.ncbi.nlm.nih.gov/35331918
Autor:
Deshan Weeraman, Daniel A. Jones, Mohsin Hussain, Anne-Marie Beirne, Steven Hadyanto, Krishnaraj S. Rathod, James R. Whiteford, Alice E. Reid, Christos V. Bourantas, Seppo Ylä-Herttuala, Andreas Baumbach, Bernard J. Gersh, Timothy D. Henry, Anthony Mathur
Publikováno v:
Journal of the Society for Cardiovascular Angiography & Interventions. 2:100527
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59fbc9975a4133b38148d6bf4bcaddf3
https://doi.org/10.1016/j.jscai.2022.100527
https://doi.org/10.1016/j.jscai.2022.100527
Autor:
Souheil El-Chemaly, Kevin Xiong, Xiaoli Liu, James R. Whiteford, Ivan O. Rosas, Sergio Poli, Sarah G. Chu, Stefan W. Ryter, Yuan Yuan Shi, Matthew J. Robertson, Bonna Ith, Giulia De Rossi, Freddy Romero, Xiaoliang Liang, Mark A. Perrella, Lindsay J. Celada, Konstantin Tsoyi, Anthony J. Esposito
Publikováno v:
Am J Respir Crit Care Med
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine
Rationale: CD148/PTRJ (receptor-like protein tyrosine phosphatase η) exerts antifibrotic effects in experimental pulmonary fibrosis via interactions with its ligand syndecan-2; however, the role of CD148 in human pulmonary fibrosis remains incomplet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879c983a151290dcff09ccb340d0a4ee
https://europepmc.org/articles/PMC8513593/
https://europepmc.org/articles/PMC8513593/