Zobrazeno 1 - 10
of 25
pro vyhledávání: '"James R. Wareing"'
Autor:
Lan-Ying Qin, Kurt W. Saionz, Roland E. Dolle, Baldwin John J, Marc-Raleigh Brescia, Joan J. Zhang, James R. Wareing, Ian R. Henderson, Juerg Zimmermann, Axel Metzger, Pascal Rigollier, Hubert Gstach, Andrew G. Cole
Publikováno v:
Tetrahedron Letters. 51:4486-4489
A facile synthesis of novel 2-amino-6-arylmethyl-7-carboxamido-7,8-dihydropyrimido[5,4-f][1,4]thiazepin-5-ones is described. The synthesis was developed on solid phase and was applied to provide a series of analogs in good yield. The key reactions ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::612c6229b945ede53f82e56c7f50e463
https://doi.org/10.1016/j.tetlet.2010.06.070
https://doi.org/10.1016/j.tetlet.2010.06.070
Autor:
Hubert Gstach, Andrew G. Cole, Ian R. Henderson, Baldwin John J, Juerg Zimmermann, Roland E. Dolle, Lan-Ying Qin, James R. Wareing, Wolfgang K.-D. Brill, Axel Metzger, Kurt W. Saionz, Marc-Raleigh Brescia
Publikováno v:
Tetrahedron Letters. 50:7082-7085
An efficient and general synthesis of substituted 2-amino-7,8-dihydropteridin-6(5H)-ones using a combination of solution-phase and solid-phase chemistry is described. Solution-phase chemistry was used to produce two pyrimidine regioisomers that were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::226ff5b78225e18bf164076aa818b1f5
https://doi.org/10.1016/j.tetlet.2009.10.005
https://doi.org/10.1016/j.tetlet.2009.10.005
Publikováno v:
The Journal of Organic Chemistry. 63:8486-8490
Affinity NMR can be used to produce an edited NMR spectrum that identifies ligands that bind to vancomycin from solution mixtures containing nonbinding molecules. The Diffusion EnCODEd Spectroscopy (DECODES) experiment performed directly on the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20433e8cea0a2c18c40e9c98a2135077
https://doi.org/10.1021/jo9817366
https://doi.org/10.1021/jo9817366
Autor:
James R. Wareing, Konrad H. Bleicher
Publikováno v:
Tetrahedron Letters. 39:4587-4590
A 9-phenylfluoren-9-yl polystyrene based resin is described for the attachment of nitrogen and oxygen nucleophiles. Higher acid stability compared to standard trityl resins makes this solid support an interesting alternative in solid phase organic sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fde39231d0643e32b0a63ff3ae828ac
https://doi.org/10.1016/s0040-4039(98)00845-4
https://doi.org/10.1016/s0040-4039(98)00845-4
Autor:
James R. Wareing, Konrad H. Bleicher
Publikováno v:
Tetrahedron Letters. 39:4591-4594
A 9-phenylfluoren-9-yl based linker for the immobilization of nitrogen and oxygen nucleophiles is described. Improved acid stability compared to the common trityl linker is demonstrated by a quantitative method for analysis of loading. This new linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ca32491538b9ba87fd003109aec579
https://doi.org/10.1016/s0040-4039(98)00846-6
https://doi.org/10.1016/s0040-4039(98)00846-6
Publikováno v:
The Journal of Organic Chemistry. 63:386-390
When sufficient material is available, NMR spectroscopy is unsurpassed for detailed structure determination in solution. However, the application of NMR to the determination of structure in multicomponent organic chemical systems prior to physical se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f7eb11a25fd803b665836d0a416ce8a
https://doi.org/10.1021/jo9713666
https://doi.org/10.1021/jo9713666
Publikováno v:
Tetrahedron. 50:3849-3856
Potent squalene synthase inhibitor 1 was converted to the bis(trifluoromethyl) analog 14 in 11% overall yield for 9 steps. The amine nitrogen of 1 was protected with the 2-(trimethylsilyl)ethoxycarbonyl (TEOC) protecting group. The 10,11 olefin was s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08170cc3d9a9b07be38e9272871be27a
https://doi.org/10.1016/s0040-4020(01)89661-7
https://doi.org/10.1016/s0040-4020(01)89661-7
Publikováno v:
European Journal of Medicinal Chemistry. 28:527-531
The synthesis and squalene synthetase inhibitory activity of farnesyl phosphinato(dialkylmethyl)phosphonates has been described. The phosphinato(dimethylmethyl)phosphonate group provided a suitable mimic of pyrophosphate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6820c592bfd7cb978ded975a33adc96
https://doi.org/10.1016/0223-5234(93)90022-7
https://doi.org/10.1016/0223-5234(93)90022-7
Autor:
James R. Wareing, Qing Tang
Publikováno v:
Tetrahedron Letters. 42:1399-1401
Resin-bound di-olefins were treated to metathesis conditions and both intramolecular ‘ring-closing’ metathesis (RCM) and intermolecular ‘cross’ metathesis were observed. Mono-olefin analogs produced dimers in high yield via intermolecular met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ced8fa841c7c3a4c9cdbe849a090025
https://doi.org/10.1016/s0040-4039(00)02228-0
https://doi.org/10.1016/s0040-4039(00)02228-0
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37b23429b925fd72144a2a2d675efba3
https://doi.org/10.1002/chin.199244148
https://doi.org/10.1002/chin.199244148