Výsledky vyhledávání - "James R. Plautz"

Preliminary clinical pharmacokinetic evaluation of bemotrizinol - A new sunscreen active ingredient being considered for inclusion under FDA's over-the-counter (OTC) sunscreen monograph

Autor: Carl D. D'Ruiz, James R. Plautz, Rolf Schuetz, Carlos Sanabria, Jody Hammonds, Cassandra Erato, Jochen Klock, Juergen Vollhardt, Szilvia Mesaros

Publikováno v: Regulatory Toxicology and Pharmacology. 139:105344

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c67e6245a4ab79af69c554089613898
https://doi.org/10.1016/j.yrtph.2023.105344

Zobrazit plný text záznamu

Using in vitro/in silico data for consumer safety assessment of feed flavoring additives – A feasibility study using piperine

Autor: James R. Plautz, Anette Thiel, E. Fabian, S. Etheve, W.R. Leeman

Publikováno v: Regulatory Toxicology and Pharmacology. 73(1):73-84

Consumer health risk assessment for feed additives is based on the estimated human exposure to the additive that may occur in livestock edible tissues compared to its hazard. We present an approach using alternative methods for consumer health risk a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27968aa8d6f0c04e3e25ce6ce18ddedc

Zobrazit plný text záznamu

Assessing the safety of cosmetic chemicals: Consideration of a flux decision tree to predict dermally delivered systemic dose for comparison with oral TTC (Threshold of Toxicological Concern)

Autor: Helga Rothe, Alessandro Chiodini, Mark T. D. Cronin, Clive Roper, Nancy A. Monteiro-Riviere, Joost Westerhout, Richard H. Guy, Jacqueline Whyte, Faith M. Williams, Chihae Yang, Gordon Barrett, James R. Plautz

Publikováno v: Regulatory toxicology and pharmacology : RTP. 76

Threshold of Toxicological Concern (TTC) aids assessment of human health risks from exposure to low levels of chemicals when toxicity data are limited. The objective here was to explore the potential refinement of exposure for applying the oral TTC t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266eda6dcb6cf569affcf618a2a47119
https://pubmed.ncbi.nlm.nih.gov/26825378

Zobrazit plný text záznamu

Triclosan and anuran metamorphosis: no effect on thyroid-mediated metamorphosis in Xenopus laevis

Autor: Robert Peter, Robert L. Rogers, James R. Plautz, Joseph W. Gorsuch, Douglas J. Fort, Lisa T. Navarro

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology. 113(2)

Nieuwkoop and Faber stage 51 Xenopus laevis larvae were exposed for 21 days to four different concentrations of triclosan (TCS):0.2 (control), 0.6, 1.5, 7.2, or 32.3 microg TCS/l. Primary endpoints were survival, hind limb length, body length (whole;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78001f96a59cb3c9e69864a544c482b
https://pubmed.ncbi.nlm.nih.gov/21071727

Zobrazit plný text záznamu

Threshold of toxicological concern (TTC) task force: a strategy to support application of TTC to dermally applied cosmetic ingredients

Autor: Richard H. Guy, Massimo Ambrosio, Faith M. Williams, Helga Rothe, James R. Plautz, Gordon Barrett, Mark T. D. Cronin, Clive Roper, M. Verwei, Chihae Yang, Diego Rua

Publikováno v: Toxicology Letters. 221:S35

Threshold of Toxicological Concern (TTC) is a tool that aids assessment of human health risks from exposure to low levels of chemicals in the diet, when specific toxicity data are not available. It provides threshold toxicity values for oral dosing i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2311ccb6278b3f241d36124759401e35
https://doi.org/10.1016/j.toxlet.2013.06.125

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání