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pro vyhledávání: '"James R. Naz"'
Publikováno v:
Journal of Molecular and Cellular Cardiology. 42:582-589
Age and hypertension contribute significantly to cardiac morbidity and mortality, however the importance of each during the progression of hypertrophy is unclear. This investigation examined the effect of age and hypertension on Ca(2+) handling in ra
Autor:
Mark D. Graham, James R. Naz, Mark R. Fowler, Simon M. Harrison, Gilles Bru-Mercier, Clive H. Orchard
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H2431-H2438
Hypertension-induced cardiac hypertrophy alters the amplitude and time course of the systolic Ca2+transient of subepicardial and subendocardial ventricular myocytes. The present study was designed to elucidate the mechanisms underlying these changes.