Zobrazeno 1 - 10
of 87
pro vyhledávání: '"James R. Moyer"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionNew learning results in modulation of intrinsic plasticity in the underlying brain regions. Such changes in intrinsic plasticity can influence allocation and encoding of future memories such that new memories encoded during the period of
Externí odkaz:
https://doaj.org/article/f0ce1e8f73d742738312cb9ff2b711bf
Publikováno v:
Brain and Behavior, Vol 10, Iss 11, Pp n/a-n/a (2020)
Abstract Introduction Cognitive deficits during aging are pervasive across species and learning paradigms. One of the major mechanisms thought to play a role in age‐related memory decline is dysregulated calcium (Ca2+) homeostasis. Aging is associa
Externí odkaz:
https://doaj.org/article/6fb191189aa0472096077ed2d10fad37
Publikováno v:
Neurobiol Aging
Brain aging is accompanied by an accumulation of damaged proteins, which results from deterioration of cellular quality control mechanisms and decreased protein degradation. The ubiquitin-proteasome system (UPS) is the primary proteolytic mechanism r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddc5059fd04a65df7092da8a9669025
https://doi.org/10.1016/j.neurobiolaging.2020.03.001
https://doi.org/10.1016/j.neurobiolaging.2020.03.001
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79002 (2013)
Ischemic stroke affects ∼795,000 people each year in the U.S., which results in an estimated annual cost of $73.7 billion. Calcium is pivotal in a variety of neuronal signaling cascades, however, during ischemia, excess calcium influx can trigger e
Externí odkaz:
https://doaj.org/article/af88263b7ce54a9ab905327b900cac30
Publikováno v:
Brain and Behavior, Vol 10, Iss 11, Pp n/a-n/a (2020)
Brain and Behavior
Brain and Behavior
Introduction Cognitive deficits during aging are pervasive across species and learning paradigms. One of the major mechanisms thought to play a role in age‐related memory decline is dysregulated calcium (Ca2+) homeostasis. Aging is associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888183a91025e6c52b16ae04bdf8dc7a
https://doaj.org/article/6fb191189aa0472096077ed2d10fad37
https://doaj.org/article/6fb191189aa0472096077ed2d10fad37
Publikováno v:
Neurobiol Learn Mem
Experience-dependent neuronal plasticity is a fundamental substrate of learning and memory. Intrinsic excitability is a form of neuronal plasticity that can be altered by learning and indicates the pattern of neuronal responding to external stimuli (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02792d4868a621e496953d81f5742630
https://doi.org/10.1016/j.nlm.2019.107132
https://doi.org/10.1016/j.nlm.2019.107132
Publikováno v:
The Journal of Neuroscience. 35:13511-13524
Neuronal activity in medial prefrontal cortex (mPFC) is critical for the formation of trace fear memory, yet the cellular mechanisms underlying these memories remain unclear. One possibility involves the modulation of intrinsic excitability within mP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b5004a648ee64d01d43715bda9ef08
https://doi.org/10.1523/jneurosci.2329-15.2015
https://doi.org/10.1523/jneurosci.2329-15.2015
Publikováno v:
Neurobiology of Learning and Memory. 105:186-199
"Use it or lose it" is a popular adage often associated with use-dependent enhancement of cognitive abilities. Much research has focused on understanding exactly how the brain changes as a function of experience. Such experience-dependent plasticity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed336d49db0a1243e8b1f8fe66117760
https://doi.org/10.1016/j.nlm.2013.07.008
https://doi.org/10.1016/j.nlm.2013.07.008
Publikováno v:
Journal of Neurophysiology. 107:3397-3408
Experience-dependent synaptic and intrinsic plasticity are thought to be important substrates for learning-related changes in behavior. The present study combined trace fear conditioning with both extracellular and intracellular hippocampal recording
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f36ee9a0be95add182ef8eb066815d7
https://doi.org/10.1152/jn.00692.2011
https://doi.org/10.1152/jn.00692.2011