Zobrazeno 1 - 5
of 5
pro vyhledávání: '"James R. Knabb"'
Supplementary Data from Elevated Poly-(ADP-Ribose)-Polymerase Activity Sensitizes Retinoblastoma-Deficient Cells to DNA Damage–Induced Necrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7a276a5d3dc2fe1a3883a91f8771e7
https://doi.org/10.1158/1541-7786.22519360.v1
https://doi.org/10.1158/1541-7786.22519360.v1
The retinoblastoma (Rb) tumor suppressor is a key regulator of cell cycle checkpoints but also protects against cell death induced by stresses such as DNA damage and death receptor ligation. We report here that cell death of Rb-deficient cells expose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d7ef114905054723f27a5900bb60f1
https://europepmc.org/articles/PMC2994938/
https://europepmc.org/articles/PMC2994938/
Autor:
Christian, Kuntzen, Francesca, Zazzeroni, Can G, Pham, Salvatore, Papa, Concetta, Bubici, James R, Knabb, Guido, Franzoso
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 399
NF-KappaB/Rel transcription factors are critical regulators of immunity, inflammation, development, and cell survival. Activation of NF-KB inhibits programmed cell death (PCD) triggered by tumor necrosis factor alpha (TNFalpha) and several other stim
Autor:
Benjamin T. Spike, Kay F. Macleod, Paul T. Schumacker, James R. Knabb, Kristin Tracy, Benjamin C. Dibling
Hypoxia and nutrient deprivation are environmental stresses governing the survival and adaptation of tumor cells in vivo. We have identified a novel role for the Rb tumor suppressor in protecting against nonapoptotic cell death in the developing mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566d830a882b9bb0b06d01a9247b4b7a
https://europepmc.org/articles/PMC1952167/
https://europepmc.org/articles/PMC1952167/
Autor:
Francesca Zazzeroni, Christian Kuntzen, Can G. Pham, Salvatore Papa, Concetta Bubici, Guido Franzoso, Kathryn Dean, James R. Knabb
Publikováno v:
Cell death and differentiation. 13(5)
NF-kappaB/Rel transcription factors have recently emerged as crucial regulators of cell survival. Activation of NF-kappaB antagonizes programmed cell death (PCD) induced by tumor necrosis factor-receptors (TNF-Rs) and several other triggers. This pro