Zobrazeno 1 - 10
of 328
pro vyhledávání: '"James R. Howe"'
Autor:
Bryan Mouser, James R. Howe, Olivia Atari, Joseph S. Dillon, Chandrikha Chandrasekharan, Kalpaj R. Parekh, Mohammad A. Bashir
Publikováno v:
International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 22, Iss , Pp 200293- (2024)
Background: Screening for carcinoid heart disease (CHD), has historically lacked consensus expert guidelines. In 2017, the North American Neuroendocrine Tumor Society (NANETS) released expert recommendations for CHD screening among NET patients to im
Externí odkaz:
https://doaj.org/article/01090077a76b411594a5d912cac2c552
Autor:
Hayley Vaughn, Heather Major, Evangeline Kadera, Kendall Keck, Timothy Dunham, Qining Qian, Bartley Brown, Aaron Scott, Andrew M. Bellizzi, Terry Braun, Patrick Breheny, Dawn E. Quelle, James R. Howe, Benjamin Darbro
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7532 (2024)
Functional copy-number alterations (fCNAs) are DNA copy-number changes with concordant differential gene expression. These are less likely to be bystander genetic lesions and could serve as robust and reproducible tumor biomarkers. To identify candid
Externí odkaz:
https://doaj.org/article/2c972b865feb4d57b55bd600bf317f8d
Autor:
Sourat Darabi, James R. Howe, Mackenzie D. Postel, Michael J. Demeure, Winnie S. Liang, David W. Craig
Publikováno v:
F1000Research, Vol 12 (2023)
Background: Small intestine neuroendocrine tumors (SI-NETs), also called “carcinoids,” are insidious tumors that are often metastatic when diagnosed. Limited studies on the mutational landscape of small bowel carcinoids indicate that these tumors
Externí odkaz:
https://doaj.org/article/916d3fb7284b404da52066bed17a902d
Autor:
Lucas Pietan, Hayley Vaughn, James R. Howe, Andrew M. Bellizzi, Brian J. Smith, Benjamin Darbro, Terry Braun, Thomas Casavant
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17401 (2023)
Determining neuroendocrine tumor (NET) primary sites is pivotal for patient care as pancreatic NETs (pNETs) and small bowel NETs (sbNETs) have distinct treatment approaches. The diagnostic power and prioritization of fluorescence in situ hybridizatio
Externí odkaz:
https://doaj.org/article/cf915e3c7f264353a67f600bfb374055
Autor:
James R. Howe
Publikováno v:
Annals of Gastroenterological Surgery, Vol 6, Iss 1, Pp 17-28 (2022)
Abstract Knowledge of the genetic basis of colorectal cancer has evolved over the past decades, allowing for the pre‐symptomatic identification of affected patients in those with familial syndromes and to the understanding of the multi‐step progr
Externí odkaz:
https://doaj.org/article/37d94f2cc58c4e3b8bdb94f4cd51fbcb
Autor:
Aaron D. Levy, Xiao Xiao, Juliana E. Shaw, Suma Priya Sudarsana Devi, Sara Marie Katrancha, Anton M. Bennett, Charles A. Greer, James R. Howe, Kazuya Machida, Anthony J. Koleske
Publikováno v:
Cell Reports, Vol 24, Iss 6, Pp 1523-1535 (2018)
Summary: Hyperactivating mutations in the non-receptor tyrosine phosphatase SHP2 cause Noonan syndrome (NS). NS is associated with cognitive deficits, but how hyperactivation of SHP2 in NS changes neuron function is not well understood. We find that
Externí odkaz:
https://doaj.org/article/2fcf40d6c87c43689141ac463046f066
Autor:
Christoph Straub, Yoav Noam, Toshihiro Nomura, Miwako Yamasaki, Dan Yan, Herman B. Fernandes, Ping Zhang, James R. Howe, Masahiko Watanabe, Anis Contractor, Susumu Tomita
Publikováno v:
Cell Reports, Vol 16, Iss 2, Pp 531-544 (2016)
Synaptic communication between neurons requires the precise localization of neurotransmitter receptors to the correct synapse type. Kainate-type glutamate receptors restrict synaptic localization that is determined by the afferent presynaptic connect
Externí odkaz:
https://doaj.org/article/107a1aa316a04f4db9a8de0087bb6ac0
Autor:
Ioannis A. Ziogas, Panagiotis T. Tasoudis, Luis C. Borbon, Scott K. Sherman, Patrick J. Breheny, Chandrikha Chandrasekharan, Joseph S. Dillon, Andrew M. Bellizzi, James R. Howe
Publikováno v:
Annals of Surgical Oncology. 30:148-160
Autor:
Servando Hernandez Vargas, Solmaz AghaAmiri, Sukhen C. Ghosh, Michael P. Luciano, Luis C. Borbon, Po Hien Ear, James R. Howe, Jennifer M. Bailey-Lundberg, Gregory D. Simonek, Daniel M. Halperin, Hop S. Tran Cao, Naruhiko Ikoma, Martin J. Schnermann, Ali Azhdarinia
Publikováno v:
Molecular Pharmaceutics. 19:4241-4253
Dye design can influence the ability of fluorescently labeled imaging agents to generate tumor contrast and has become an area of significant interest in the field of fluorescence-guided surgery (FGS). Here, we show that the charge-balanced near-infr
Autor:
Luis C. Borbon, Catherine G. Tran, Scott K. Sherman, Po Hien Ear, Chandrikha Chandrasekharan, Andrew M. Bellizzi, Joseph S. Dillon, Thomas M. O’Dorisio, James R. Howe
Publikováno v:
Annals of Surgical Oncology. 29:6936-6946