Zobrazeno 1 - 10
of 26
pro vyhledávání: '"James R. Hauske"'
Autor:
James R. Hauske, Keith W. Miller, Gregory D. Cuny, Nico Caggiano, Brunello Oliva, Michael Z. Hoemann, Ian Chopra, Alex J. O'Neill
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:458-466
The antibacterial properties of novel quinoline-indole (QI) agents were examined. QI agents demonstrated potent bactericidal activities against Staphylococcus aureus , killing by lytic and nonlytic mechanisms. S. aureus mutants resistant to a lytic Q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f8007e15f33f92a60dd1563ea432a0
https://doi.org/10.1128/aac.47.2.458-466.2003
https://doi.org/10.1128/aac.47.2.458-466.2003
Autor:
Michael Z. Hoemann, Roger L. Xie, Richard F. Rossi, Sylvia Meyer, Alban Sidhu, Gregory D. Cuny, James R. Hauske
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:129-132
Novel antibacterials agents, 2-(1H-indol-3-yl)tetrahydroquinolines, were prepared using hetero Diels-Alder chemistry and found to be effective in vitro against methicillin-resistant Staphylococcus aureus (MRSA). A structure-activity relationship (SAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a8eb3d873c9f264443a85f2df1fbc4
https://doi.org/10.1016/s0960-894x(01)00714-4
https://doi.org/10.1016/s0960-894x(01)00714-4
Autor:
James R. Hauske, Roger Xie
Publikováno v:
Tetrahedron Letters. 41:10167-10170
The investigation of palladium-catalyzed alkoxyallylation of activated olefins, followed by ring-closing metathesis to synthesize functionalized seven-membered ring allyl ethers is described. The influence of the olefin substituents on the diastereos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cf02681ef09ecdb4bd47341b40faade
https://doi.org/10.1016/s0040-4039(00)01834-7
https://doi.org/10.1016/s0040-4039(00)01834-7
Publikováno v:
Tetrahedron. 55:8169-8178
The solution-phase ring opening cross-metathesis (ROM) of bicyclic alkenes with styrene derivatives is described. The influence of bicyclic alkene substituents on the rate and product distribution of solution-phase ROM reactions with styrene derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d692f351ed9fff02ed21512621bf3b13
https://doi.org/10.1016/s0040-4020(99)00298-7
https://doi.org/10.1016/s0040-4020(99)00298-7
Publikováno v:
Tetrahedron Letters. 39:4749-4752
Using heterocyclic- N -oxide chemistry, various substituted quinoline and isoquinoline compounds were synthesized on the solid support in excellent purity and good to excellent yield.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1c1fab38e2a0c32aa89adb3938eeb2e
https://doi.org/10.1016/s0040-4039(98)01005-3
https://doi.org/10.1016/s0040-4039(98)01005-3
Autor:
Fengjiang Wang, James R. Hauske
Publikováno v:
Tetrahedron Letters. 38:8651-8654
A novel, facile and efficient method for the synthesis of aryl iminophosphorane has been developed by treating a series of ArNH 2 ( 1 ) attached to a solid support with Ph 3 P and diethyl azodicarboxylate at room temperature. The resulting solid-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2cb9c1bfee1a9c3e41d8f781de1273e
https://doi.org/10.1016/s0040-4039(97)10377-x
https://doi.org/10.1016/s0040-4039(97)10377-x
Publikováno v:
Tetrahedron Letters. 38:5237-5240
Ring opening cross-metathesis (ROM) of bicyclic alkenes with terminal aryl alkenes on solid support was accomplished. A select group of resin-bound bicyclic alkenes underwent highly regioselective ROM with electron rich styrenes. The influence of bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6c5a7c47fc1178ce6c5bb607538a194
https://doi.org/10.1016/s0040-4039(97)01144-1
https://doi.org/10.1016/s0040-4039(97)01144-1
Publikováno v:
Molecular Diversity. 3:173-179
Ruthenium catalyzed ring opening cross-metathesis of resin-bound bicyclic alkenes with terminal aryl olefins was utilized for the construction of a combinatorial library containing highly functionalized cyclopentane derivatives. The technology descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::235ee698f034f039145ea9da27cb34c4
https://doi.org/10.1023/a:1009663720800
https://doi.org/10.1023/a:1009663720800
Publikováno v:
Tetrahedron Letters. 36:4567-4570
The palladium promoted vinylation of aryl iodide bound to a solid support was studied. Under the reaction conditions of water/DMF/Pd(OAc) 2 /PPh 3 /base, the reaction proceeds smoothly and leads to moderate to high yield of product at 37°C after 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f7703cb1025d99343d3266fb044ea54
https://doi.org/10.1016/0040-4039(95)00855-7
https://doi.org/10.1016/0040-4039(95)00855-7
Autor:
Dorff Peter H, James R. Hauske
Publikováno v:
Tetrahedron Letters. 36:1589-1592
Treatment of TentaGel S resin (1) with phosgene provides matrix linked chloroformate (2), which is converted to the corresponding carbamoylated derivatives 3a and 3b. Alternatively, Wang resin provides the imidazolide (7a), which is readily transform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff1a45aae25933f5fc7ae527ba39173
https://doi.org/10.1016/0040-4039(95)00095-t
https://doi.org/10.1016/0040-4039(95)00095-t