Zobrazeno 1 - 10
of 211
pro vyhledávání: '"James R. Halpert"'
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1025 (2018)
The over two dozen CYP2B structures of human, rabbit, and woodrat enzymes solved in the last decade have significantly enhanced our understanding of the structure-function relationships of drug metabolizing enzymes. More recently, an important role h
Externí odkaz:
https://doaj.org/article/4c0c6fc71beb41289beeac46a510dfeb
Publikováno v:
Genomics Data, Vol 9, Iss C, Pp 58-59 (2016)
We present the de novo draft genome sequence for a vertebrate mammalian herbivore, the desert woodrat (Neotoma lepida). This species is of ecological and evolutionary interest with respect to ingestion, microbial detoxification and hepatic metabolism
Externí odkaz:
https://doaj.org/article/014b2c9e1b2f4293b7dbaea0a4bb57ab
Publikováno v:
Drug Metabolism and Disposition. 51:105-110
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 95
The vast diversity of cytochrome P450 enzymes in mammals has been proposed to result in large measure from plant-animal warfare, whereby evolution of chemical defenses such as phenolics and terpenoids in plants led to duplication and divergence of P4
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 51(1)
This article was solicited to commemorate the 50th anniversary of
Publikováno v:
Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary ISBN: 9780323911092
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81afa3ebfc9b83f13fa1402225de4800
https://doi.org/10.1016/bs.apha.2022.05.002
https://doi.org/10.1016/bs.apha.2022.05.002
Autor:
M. Denise Dearing, P. Ross Wilderman, Michele M. Skopec, James R. Halpert, Katharina Schramm, Teri J. Orr, Smiljka Kitanovic
Publikováno v:
Molecular Ecology. 29:1674-1683
Although herbivory is widespread among mammals, few species have adopted a strategy of dietary specialization. Feeding on a single plant species often exposes herbivores to high doses of plant secondary metabolites (PSMs), which may exceed the animal
Autor:
James R. Halpert
Publikováno v:
Journal of Biological Chemistry. 295:822-832
I have traveled many roads during my career. After spending my first 19 years in Los Angeles, I became somewhat of an academic nomad, studying and/or working in six universities in the United States and three in Sweden. In chronological order, I have
Autor:
Chad A Marks-Fife, M. Denise Dearing, James R. Halpert, Quincy A Parkes, P. Ross Wilderman, Smiljka Kitanovic
Publikováno v:
Journal of Mammalogy. 99:578-585
Although herbivores rely on liver enzymes to biotransform plant secondary metabolites ingested in plant-based diets, only a few enzymes from a handful of species have been characterized at the genomic level. In this study, we examined cytochrome P450
Autor:
Ross Wilderman, James R. Halpert
Publikováno v:
The FASEB Journal. 33